LTRL590_200007700

deoxyhypusine synthase, putative

Leishmania tropica L590 OG6: OG6_101093 OG7: OG7_0005231 138 interactions (filtered)

Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used

Source datasets

T.brucei_2016_Gazestani

T.brucei_2017_Crozier

L.donovani_2025_Azimi

T.cruzi_2025_Azimi

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Network view up to 80 partners

Query Computational only Exp + computational Experimental only

Interactions 138 total

Partner	Experimental (Co-frac/MS)	Computational (OG inference)	OG
LTRL590_340008500 ⚠ deoxyhypusine synthase	—	OG6 TCSYLVIO_004558 ↔ TCSYLVIO_007258 OG6 Tb927.1.870 ↔ Tb927.10.2750 OG7 Tb927.1.870 ↔ Tb927.10.2750 OG7 TCSYLVIO_004558 ↔ TCSYLVIO_007258	Both
LTRL590_360051800 ⚠ glycosyl hydrolase-like protein	—	OG7 TCSYLVIO_006140 ↔ TCSYLVIO_007258 OG7 TCSYLVIO_006141 ↔ TCSYLVIO_007258 OG7 TCSYLVIO_004558 ↔ TCSYLVIO_006140 OG7 TCSYLVIO_004558 ↔ TCSYLVIO_006141	OG7
LTRL590_300015300 ⚠ ubiquitin-protein ligase, putative	—	OG6 TCSYLVIO_003155 ↔ TCSYLVIO_004558 OG7 TCSYLVIO_003155 ↔ TCSYLVIO_004558	Both
LTRL590_300035400 ⚠ DNA ligase I, putative	—	OG6 TCSYLVIO_003375 ↔ TCSYLVIO_004558 OG6 TCSYLVIO_003375 ↔ TCSYLVIO_007258 OG7 TCSYLVIO_003375 ↔ TCSYLVIO_004558 OG7 TCSYLVIO_003375 ↔ TCSYLVIO_007258	Both
LTRL590_300037200 ⚠ UV excision repair RAD23-like protein	—	OG6 TCSYLVIO_003361 ↔ TCSYLVIO_004558 OG6 TCSYLVIO_003361 ↔ TCSYLVIO_007258 OG7 TCSYLVIO_003361 ↔ TCSYLVIO_004558 OG7 TCSYLVIO_003361 ↔ TCSYLVIO_007258	Both
LTRL590_180005000 ⚠ kinetoplast polyadenylation/uridylation facto	—	OG6 TCSYLVIO_000834 ↔ TCSYLVIO_004558 OG6 TCSYLVIO_000834 ↔ TCSYLVIO_007258 OG7 TCSYLVIO_000834 ↔ TCSYLVIO_004558 OG7 TCSYLVIO_000834 ↔ TCSYLVIO_007258	Both
LTRL590_290028300 ⚠ UDP-glucose:Glycoprotein Glucosyltransferase,	—	OG6 TCSYLVIO_004363 ↔ TCSYLVIO_004558 OG6 TCSYLVIO_004363 ↔ TCSYLVIO_007258 OG7 TCSYLVIO_004363 ↔ TCSYLVIO_004558 OG7 TCSYLVIO_004363 ↔ TCSYLVIO_007258	Both
LTRL590_060008500 ⚠ serine peptidase, clan SC, family S9A-like pr	—	OG6 TCSYLVIO_006546 ↔ TCSYLVIO_007258 OG7 TCSYLVIO_006546 ↔ TCSYLVIO_007258	Both
LTRL590_090013200 ⚠ oligopeptidase b	—	OG6 TCSYLVIO_006546 ↔ TCSYLVIO_007258 OG7 TCSYLVIO_006546 ↔ TCSYLVIO_007258	Both
LTRL590_220010900 ⚠ Uncharacterised protein family UPF0066, putat	—	OG6 TCSYLVIO_001255 ↔ TCSYLVIO_007258 OG7 TCSYLVIO_001255 ↔ TCSYLVIO_007258	Both
LTRL590_220016400 ⚠ translation initiation factor IF-2, putative	—	OG6 TCSYLVIO_001768 ↔ TCSYLVIO_004558 OG6 TCSYLVIO_001768 ↔ TCSYLVIO_007258 OG7 TCSYLVIO_001768 ↔ TCSYLVIO_004558 OG7 TCSYLVIO_001768 ↔ TCSYLVIO_007258	Both
LTRL590_260017700 ⚠ Cupin-like domain containing protein, putativ	—	OG6 TCSYLVIO_002279 ↔ TCSYLVIO_004558 OG7 TCSYLVIO_002279 ↔ TCSYLVIO_004558	Both
LTRL590_050012700 ⚠ hypothetical protein, conserved	—	OG6 TCSYLVIO_001973 ↔ TCSYLVIO_004558 OG6 TCSYLVIO_001973 ↔ TCSYLVIO_007258 OG7 TCSYLVIO_001973 ↔ TCSYLVIO_004558 OG7 TCSYLVIO_001973 ↔ TCSYLVIO_007258	Both
LTRL590_270031400 ⚠ TPR-repeat protein, putative	—	OG6 TCSYLVIO_003496 ↔ TCSYLVIO_004558 OG6 TCSYLVIO_003496 ↔ TCSYLVIO_007258	OG6
LTRL590_360005600 ⚠ stress-inducible protein STI1 homolog	—	OG6 TCSYLVIO_003496 ↔ TCSYLVIO_004558 OG6 TCSYLVIO_003496 ↔ TCSYLVIO_007258	OG6
LTRL590_220019900 ⚠ alanyl-tRNA synthetase, putative	—	OG6 TCSYLVIO_001889 ↔ TCSYLVIO_004558 OG6 TCSYLVIO_001889 ↔ TCSYLVIO_007258 OG7 TCSYLVIO_001889 ↔ TCSYLVIO_004558 OG7 TCSYLVIO_001889 ↔ TCSYLVIO_007258	Both
LTRL590_280009400 ⚠ DIS3-like exonuclease, putative	—	OG6 TCSYLVIO_002525 ↔ TCSYLVIO_004558 OG6 TCSYLVIO_002526 ↔ TCSYLVIO_004558 OG6 TCSYLVIO_002525 ↔ TCSYLVIO_007258 OG6 TCSYLVIO_002526 ↔ TCSYLVIO_007258 +4 more	Both
LTRL590_320048000 ⚠ Gar1/Naf1 RNA binding region containing prote	—	OG6 TCSYLVIO_000836 ↔ TCSYLVIO_004558 OG6 TCSYLVIO_000836 ↔ TCSYLVIO_007258 OG7 TCSYLVIO_000836 ↔ TCSYLVIO_004558 OG7 TCSYLVIO_000836 ↔ TCSYLVIO_007258	Both
LTRL590_030014700 ⚠ inorganic pyrophosphatase, putative	—	OG6 TCSYLVIO_001709 ↔ TCSYLVIO_004558 OG6 TCSYLVIO_001709 ↔ TCSYLVIO_007258 OG7 TCSYLVIO_001709 ↔ TCSYLVIO_004558 OG7 TCSYLVIO_001709 ↔ TCSYLVIO_007258	Both
LTRL590_110007200 ⚠ acidocalcisomal pyrophosphatase	—	OG6 TCSYLVIO_001709 ↔ TCSYLVIO_004558 OG6 TCSYLVIO_001709 ↔ TCSYLVIO_007258 OG7 TCSYLVIO_001709 ↔ TCSYLVIO_004558 OG7 TCSYLVIO_001709 ↔ TCSYLVIO_007258	Both
LTRL590_000009900 ⚠ serine/threonine protein kinase sos2, putativ	—	OG7 TCSYLVIO_004355 ↔ TCSYLVIO_004558	OG7
LTRL590_360014900 ⚠ SNF1-related protein kinases, putative	—	OG7 TCSYLVIO_004355 ↔ TCSYLVIO_004558	OG7
LTRL590_330024900 ⚠ protein kinase, putative	—	OG7 TCSYLVIO_004355 ↔ TCSYLVIO_004558	OG7
LTRL590_180011900 ⚠ serine/threonine kinase-like protein, putativ	—	OG7 TCSYLVIO_004355 ↔ TCSYLVIO_004558	OG7
LTRL590_280027500 ⚠ protein kinase, putative	—	OG7 TCSYLVIO_004355 ↔ TCSYLVIO_004558	OG7
LTRL590_210007000 ⚠ serine/threonine-protein kinase-like protein	—	OG7 TCSYLVIO_004355 ↔ TCSYLVIO_004558	OG7
LTRL590_070016600 ⚠ serine/threonine kinase, putative	—	OG7 TCSYLVIO_004355 ↔ TCSYLVIO_004558	OG7
LTRL590_040008100 ⚠ mitochondrial exoribonuclease DSS-1, putative	—	OG7 TCSYLVIO_002525 ↔ TCSYLVIO_004558 OG7 TCSYLVIO_002526 ↔ TCSYLVIO_004558 OG7 TCSYLVIO_002525 ↔ TCSYLVIO_007258 OG7 TCSYLVIO_002526 ↔ TCSYLVIO_007258	OG7
LTRL590_280008300 ⚠ rrp44p homologue, putative	—	OG7 TCSYLVIO_002525 ↔ TCSYLVIO_004558 OG7 TCSYLVIO_002526 ↔ TCSYLVIO_004558 OG7 TCSYLVIO_002525 ↔ TCSYLVIO_007258 OG7 TCSYLVIO_002526 ↔ TCSYLVIO_007258	OG7
LTRL590_340039200 ⚠ cleavage and polyadenylation specificity fact	—	OG7 TCSYLVIO_005414 ↔ TCSYLVIO_007258 OG7 TCSYLVIO_004558 ↔ TCSYLVIO_005414	OG7
LTRL590_030006400 ⚠ ATP-binding cassette protein subfamily F, mem	—	OG7 TCSYLVIO_006012 ↔ TCSYLVIO_007258 OG7 TCSYLVIO_004558 ↔ TCSYLVIO_006012	OG7
LTRL590_330009000 ⚠ ATP-binding cassette sub-family F member 1, p	—	OG7 TCSYLVIO_006012 ↔ TCSYLVIO_007258 OG7 TCSYLVIO_004558 ↔ TCSYLVIO_006012	OG7
LTRL590_360073300 ⚠ rab-like GTPase activating protein, putative	—	OG7 TCSYLVIO_004663 ↔ TCSYLVIO_007258 OG7 TCSYLVIO_004558 ↔ TCSYLVIO_004663	OG7
LTRL590_300010300 ⚠ aspartyl-tRNA synthetase, putative	—	OG7 TCSYLVIO_003867 ↔ TCSYLVIO_004558 OG7 TCSYLVIO_003867 ↔ TCSYLVIO_007258	OG7
LTRL590_210016500 ⚠ aspartyl-tRNA synthetase, putative	—	OG7 TCSYLVIO_003867 ↔ TCSYLVIO_004558 OG7 TCSYLVIO_003867 ↔ TCSYLVIO_007258	OG7
LTRL590_290026700 ⚠ hypothetical protein, conserved	—	OG7 TCSYLVIO_003375 ↔ TCSYLVIO_004558 OG7 TCSYLVIO_003375 ↔ TCSYLVIO_007258	OG7
LTRL590_220009800 ⚠ Putative tRNA binding domain containing prote	—	OG7 TCSYLVIO_007258 ↔ TCSYLVIO_010624 OG7 TCSYLVIO_004558 ↔ TCSYLVIO_010624	OG7
LTRL590_260017400 ⚠ FYVE zinc finger containing protein, putative	—	OG7 TCSYLVIO_004558 ↔ TCSYLVIO_006188	OG7
LTRL590_150016300 ⚠ Rad9, putative	—	OG7 TCSYLVIO_004558 ↔ TCSYLVIO_007065	OG7
LTRL590_140019300 ⚠ ras-like small GTPases, putative	—	OG7 TCSYLVIO_004558 ↔ TCSYLVIO_006188	OG7
LTRL590_340018100 ⚠ Dihydrouridine synthase (Dus), putative	—	OG7 TCSYLVIO_007258 ↔ TCSYLVIO_009102 OG7 TCSYLVIO_004558 ↔ TCSYLVIO_009102	OG7
LTRL590_230008600 ⚠ tryptophanyl-tRNA synthetase, putative	—	OG7 TCSYLVIO_007258 ↔ TCSYLVIO_010724 OG7 TCSYLVIO_004558 ↔ TCSYLVIO_010724	OG7
LTRL590_260005500 ⚠ FYVE zinc finger containing protein, putative	—	OG7 TCSYLVIO_004558 ↔ TCSYLVIO_006188	OG7
LTRL590_350049500 ⚠ predicted zinc finger protein	—	OG7 TCSYLVIO_004558 ↔ TCSYLVIO_006188	OG7
LTRL590_190013800 ⚠ FYVE zinc finger containing protein, putative	—	OG7 TCSYLVIO_004558 ↔ TCSYLVIO_006188	OG7
LTRL590_330021400 ⚠ protein kinase, putative	—	OG7 TCSYLVIO_007258 ↔ TCSYLVIO_007401 OG7 TCSYLVIO_004558 ↔ TCSYLVIO_007401	OG7
LTRL590_260019000 ⚠ MORN repeat/FYVE zinc finger containing prote	—	OG7 TCSYLVIO_004558 ↔ TCSYLVIO_006188	OG7
LTRL590_000019000 ⚠ dihydrouridine synthase (Dus), putative	—	OG7 TCSYLVIO_007258 ↔ TCSYLVIO_009102 OG7 TCSYLVIO_004558 ↔ TCSYLVIO_009102	OG7
LTRL590_300034700 ⚠ GTPase activator-like protein	—	OG7 TCSYLVIO_004558 ↔ TCSYLVIO_008881	OG7
LTRL590_300012500 ⚠ nuclear movement protein, putative	—	OG7 TCSYLVIO_007258 ↔ TCSYLVIO_010327 OG7 TCSYLVIO_004558 ↔ TCSYLVIO_010327	OG7

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