LTRL590_240028600

3-hydroxy-3-methylglutaryl-CoA synthase, putative
Leishmania tropica L590 OG6: OG6_101064 OG7: OG7_0006553 87 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 87 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LTRL590_350008800 ⚠
ATP-dependent DEAD-box RNA helicase, putative
— OG7
LTRL590_260007600 ⚠
aminopeptidase-like protein
— OG7
LTRL590_280021900 ⚠
ATP-dependent RNA helicase FAL1, putative
— OG7
LTRL590_330024900 ⚠
protein kinase, putative
— OG7
LTRL590_280022200 ⚠
ATP-dependent RNA helicase FAL1, putative
— OG7
LTRL590_210007000 ⚠
serine/threonine-protein kinase-like protein
— OG7
LTRL590_280027500 ⚠
protein kinase, putative
— OG7
LTRL590_290027300 ⚠
serine/threonine protein kinase, putative
— OG7
LTRL590_360014900 ⚠
SNF1-related protein kinases, putative
— OG7
LTRL590_010013300 ⚠
eukaryotic initiation factor 4a, putative
— OG7
LTRL590_000009900 ⚠
serine/threonine protein kinase sos2, putativ
— OG7
LTRL590_120014700 ⚠
puromycin-sensitive aminopeptidase-like prote
— OG7
LTRL590_300032100
hypothetical protein, conserved
— OG7
LTRL590_350027000 ⚠
adenine aminohydrolase
— OG7
LTRL590_150007700 ⚠
sterol carrier protein, putative
— OG7
LTRL590_200011700
cytidine triphosphate synthase, putative
— Both
LTRL590_150017000 ⚠
tryparedoxin peroxidase
— Both
LTRL590_230005400 ⚠
peroxidoxin
— Both
LTRL590_230015400 ⚠
3-ketoacyl-CoA thiolase, putative
— Both
LTRL590_320037400
nucleoside diphosphate kinase b
— Both
LTRL590_170006900 ⚠
cystathionine beta-synthase
— Both
LTRL590_360045800 ⚠
cysteine synthase
— OG6
LTRL590_280024300 ⚠
NOL1/NOP2/sun family, putative
— OG7
LTRL590_320029300 ⚠
small nuclear ribonucleoprotein component-lik
— OG7
LTRL590_250028100 ⚠
elongation factor 2-like protein
— OG7
LTRL590_350031700 ⚠
TFIIF-stimulated CTD phosphatase, putative
— OG7
LTRL590_310006700 ⚠
nucleolar protein, putative
— OG7
LTRL590_320006000 ⚠
NLI interacting factor-like phosphatase, puta
— OG7
LTRL590_350007000 ⚠
NLI interacting factor-like phosphatase, puta
— OG7
LTRL590_350041500 ⚠
NLI interacting factor-like phosphatase, puta
— OG7
LTRL590_310006800 ⚠
hypothetical protein
— OG7
LTRL590_260006300 ⚠
nuclear lim interactor-interacting factor-lik
— OG7
LTRL590_330013700 ⚠
hypothetical protein
— OG7
LTRL590_240024800 ⚠
calcium/calmodulin-dependent protein kinase,
— Both
LTRL590_320031700 ⚠
NOL1/NOP2/sun family, putative
— OG7
LTRL590_000016700 ⚠
nuclear lim interactor-interacting factor-lik
— OG7
LTRL590_360081500 ⚠
nuclear lim interactor-interacting factor, pu
— OG7
LTRL590_290027100 ⚠
NOL1/NOP2/sun family, putative
— OG7
LTRL590_250027600 ⚠
dullard-like phosphatase domain containing pr
— OG7
LTRL590_270020700 ⚠
choline kinase
— OG7
LTRL590_330013800 ⚠
hypothetical protein
— OG7
LTRL590_290031800 ⚠
NLI interacting factor-like phosphatase, puta
— OG7
LTRL590_110007800 ⚠
serine/threonine protein kinase, putative
— OG7
LTRL590_350028600 ⚠
protein kinase, putative
— OG7
LTRL590_000012300 ⚠
elongation factor 2
— Both
LTRL590_360059300
paraflagellar rod component, putative
— Both
LTRL590_290029600
Leucine-rich repeat, putative
— Both
LTRL590_260013000
aspartate--ammonia ligase, putative
— Both
LTRL590_180011900 ⚠
serine/threonine kinase-like protein, putativ
— Both
LTRL590_210023600 ⚠
RNA helicase, putative
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.