LTRL590_240013400

malic enzyme, putative
Leishmania tropica L590 OG6: OG6_100205 OG7: OG7_0002857 55 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 55 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LTRL590_180018800 ⚠
heat shock protein 110, putative
— OG7
LTRL590_330034200 ⚠
aminopeptidase, putative
— Both
LTRL590_120011900 ⚠
alanine aminotransferase
— Both
LTRL590_230015600 ⚠
acetyl-CoA synthetase, putative
— Both
LTRL590_230011400 ⚠
acetyl-CoA synthetase, putative
— Both
LTRL590_230011300 ⚠
AMP-binding enzyme/AMP-binding enzyme C-termi
— Both
LTRL590_310045200 ⚠
phosphoglycan beta 1,3 galactosyltransferase
— Both
LTRL590_330009000 ⚠
ATP-binding cassette sub-family F member 1, p
— Both
LTRL590_300022300 ⚠
hypothetical protein, conserved
— Both
LTRL590_270025900 ⚠
trypanothione synthetase, putative
— Both
LTRL590_360080100 ⚠
2,3-bisphosphoglycerate-independent phosphogl
— Both
LTRL590_350054000 ⚠
Hsp70 protein, putative
— OG7
LTRL590_260013700 ⚠
heat shock 70 protein-like protein
— OG7
LTRL590_110013400 ⚠
Cytosol aminopeptidase family, catalytic doma
— OG7
LTRL590_260017200 ⚠
heat-shock protein hsp70, putative
— Both
LTRL590_010011800 ⚠
HSP70-like protein
— OG7
LTRL590_000006000 ⚠
aminopeptidase, putative
— OG7
LTRL590_330037600 ⚠
D-alanyl-glycyl endopeptidase-like protein
— OG7
LTRL590_250031600 ⚠
glutathionylspermidine synthase, putative
— OG7
LTRL590_230010400 ⚠
trypanothione synthetase, putative
— OG7
LTRL590_330037200 ⚠
D-alanyl-glycyl endopeptidase-like protein
— OG7
LTRL590_290024300 ⚠
paraflagellar rod protein 1D, putative
— OG7
LTRL590_290024400 ⚠
hypothetical protein
— OG7
LTRL590_360067400 ⚠
aminopeptidase P1, putative
— OG7
LTRL590_250028100 ⚠
elongation factor 2-like protein
— OG7
LTRL590_320029300 ⚠
small nuclear ribonucleoprotein component-lik
— OG7
LTRL590_030006400 ⚠
ATP-binding cassette protein subfamily F, mem
— OG7
LTRL590_190012800 ⚠
ABC transport system ATP-binding protein, put
— OG7
LTRL590_360007100 ⚠
Elongation factor G C-terminus, putative
— Both
LTRL590_000023700 ⚠
isocitrate dehydrogenase [NADP], mitochondria
— +2 more Both
LTRL590_240008200 ⚠
fumarate hydratase, putative
— Both
LTRL590_350039500 ⚠
6-phosphogluconate dehydrogenase, decarboxyla
— Both
LTRL590_290026600 ⚠
fumarate hydratase, putative
— Both
LTRL590_250028700 ⚠
succinyl-CoA synthetase alpha subunit, putati
— Both
LTRL590_240013500 ⚠
malic enzyme, putative
— Both
LTRL590_180012300 ⚠
citrate synthase, putative
— Both
LTRL590_180012400 ⚠
citrate synthase, putative
— Both
LTRL590_040014900 ⚠
hypothetical protein, conserved
— Both
LTRL590_140019200 ⚠
enolase
— Both
LTRL590_270025700 ⚠
paraflagellar rod protein-like protein
— Both
LTRL590_350028900 ⚠
aminopeptidase P, putative
— Both
LTRL590_000012300 ⚠
elongation factor 2
— Both
LTRL590_250028800 ⚠
succinyl-CoA synthetase alpha subunit, putati
— Both
LTRL590_180010400 ⚠
aconitase, putative
— Both
LTRL590_360038700 ⚠
succinyl-CoA ligase [GDP-forming] beta-chain,
— Both
LTRL590_280018200 ⚠
Hsp70 protein, putative
— Both
LTRL590_280035400 ⚠
Hsp70 protein, putative
— Both
LTRL590_280018100 ⚠
heat-shock protein hsp70, putative
— Both
LTRL590_360045800 ⚠
cysteine synthase
— Both
LTRL590_090013900 ⚠
Uncharacterised protein family (UPF0160), put
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.