LTRL590_230011400

acetyl-CoA synthetase, putative

Leishmania tropica L590 OG6: OG6_100430 OG7: OG7_0000501 46 interactions (filtered)

Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used

Source datasets

T.brucei_2016_Gazestani

T.brucei_2017_Crozier

L.donovani_2025_Azimi

T.cruzi_2025_Azimi

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Network view up to 80 partners

Query Computational only Exp + computational Experimental only

Interactions 46 total

Partner	Experimental (Co-frac/MS)	Computational (OG inference)	OG
LTRL590_170006900 ⚠ cystathionine beta-synthase	—	OG6 LdBPK_170300.1 ↔ LdBPK_230580.1 OG6 LdBPK_170300.1 ↔ LdBPK_230880.1 OG6 TCSYLVIO_000046 ↔ TCSYLVIO_008128 OG7 LdBPK_170300.1 ↔ LdBPK_230580.1 +1 more	Both
LTRL590_360045800 ⚠ cysteine synthase	—	OG6 LdBPK_170300.1 ↔ LdBPK_230580.1 OG6 LdBPK_170300.1 ↔ LdBPK_230880.1 OG6 TCSYLVIO_000046 ↔ TCSYLVIO_008128 OG7 TCSYLVIO_000046 ↔ TCSYLVIO_008128	Both
LTRL590_350028900 ⚠ aminopeptidase P, putative	—	OG6 TCSYLVIO_000046 ↔ TCSYLVIO_001380 OG7 TCSYLVIO_000046 ↔ TCSYLVIO_001380	Both
LTRL590_290024400 ⚠ hypothetical protein	—	OG7 TCSYLVIO_000046 ↔ TCSYLVIO_000425	OG7
LTRL590_240013500 ⚠ malic enzyme, putative	—	OG6 TCSYLVIO_000046 ↔ TCSYLVIO_001501 OG7 TCSYLVIO_000046 ↔ TCSYLVIO_001501	Both
LTRL590_180012300 ⚠ citrate synthase, putative	—	OG6 LdBPK_180700.1 ↔ LdBPK_230580.1 OG6 LdBPK_180700.1 ↔ LdBPK_230880.1 OG7 LdBPK_180700.1 ↔ LdBPK_230580.1 OG7 LdBPK_180700.1 ↔ LdBPK_230880.1	Both
LTRL590_180012400 ⚠ citrate synthase, putative	—	OG6 LdBPK_180700.1 ↔ LdBPK_230580.1 OG6 LdBPK_180700.1 ↔ LdBPK_230880.1 OG7 LdBPK_180700.1 ↔ LdBPK_230580.1 OG7 LdBPK_180700.1 ↔ LdBPK_230880.1	Both
LTRL590_290027100 ⚠ NOL1/NOP2/sun family, putative	—	OG7 LdBPK_230580.1 ↔ LdBPK_322580.1 OG7 LdBPK_230880.1 ↔ LdBPK_322580.1	OG7
LTRL590_280024300 ⚠ NOL1/NOP2/sun family, putative	—	OG7 LdBPK_230580.1 ↔ LdBPK_322580.1 OG7 LdBPK_230880.1 ↔ LdBPK_322580.1	OG7
LTRL590_310006800 ⚠ hypothetical protein	—	OG7 LdBPK_230580.1 ↔ LdBPK_322580.1 OG7 LdBPK_230880.1 ↔ LdBPK_322580.1	OG7
LTRL590_310006700 ⚠ nucleolar protein, putative	—	OG7 LdBPK_230580.1 ↔ LdBPK_322580.1 OG7 LdBPK_230880.1 ↔ LdBPK_322580.1	OG7
LTRL590_250022100 ⚠ PUA domain/NOL1/NOP2/sun family, putative	—	OG7 LdBPK_230580.1 ↔ LdBPK_322580.1 OG7 LdBPK_230880.1 ↔ LdBPK_322580.1	OG7
LTRL590_340022200 ⚠ Protein of unknown function (DUF3808), putati	—	OG7 LdBPK_230580.1 ↔ LdBPK_303750.1 OG7 LdBPK_230880.1 ↔ LdBPK_303750.1	OG7
LTRL590_260025400 ⚠ Methyltransferase domain containing protein,	—	OG7 LdBPK_230580.1 ↔ LdBPK_291030.1 OG7 LdBPK_230880.1 ↔ LdBPK_291030.1	OG7
LTRL590_350054000 ⚠ Hsp70 protein, putative	—	OG7 TCSYLVIO_000046 ↔ TCSYLVIO_002194	OG7
LTRL590_260013700 ⚠ heat shock 70 protein-like protein	—	OG7 TCSYLVIO_000046 ↔ TCSYLVIO_002194	OG7
LTRL590_180018800 ⚠ heat shock protein 110, putative	—	OG7 TCSYLVIO_000046 ↔ TCSYLVIO_002194	OG7
LTRL590_290024300 ⚠ paraflagellar rod protein 1D, putative	—	OG7 TCSYLVIO_000046 ↔ TCSYLVIO_000425	OG7
LTRL590_330037600 ⚠ D-alanyl-glycyl endopeptidase-like protein	—	OG7 TCSYLVIO_000046 ↔ TCSYLVIO_000427	OG7
LTRL590_250031600 ⚠ glutathionylspermidine synthase, putative	—	OG7 TCSYLVIO_000046 ↔ TCSYLVIO_000427	OG7
LTRL590_010011800 ⚠ HSP70-like protein	—	OG7 TCSYLVIO_000046 ↔ TCSYLVIO_002194	OG7
LTRL590_360067400 ⚠ aminopeptidase P1, putative	—	OG7 TCSYLVIO_000046 ↔ TCSYLVIO_001380	OG7
LTRL590_330037200 ⚠ D-alanyl-glycyl endopeptidase-like protein	—	OG7 TCSYLVIO_000046 ↔ TCSYLVIO_000427	OG7
LTRL590_230010400 ⚠ trypanothione synthetase, putative	—	OG7 TCSYLVIO_000046 ↔ TCSYLVIO_000427	OG7
LTRL590_340021100 ⚠ d-isomer specific 2-hydroxyacid dehydrogenase	—	OG6 LdBPK_044360.1 ↔ LdBPK_230580.1 OG6 LdBPK_044360.1 ↔ LdBPK_230880.1 OG7 LdBPK_044360.1 ↔ LdBPK_230580.1 OG7 LdBPK_044360.1 ↔ LdBPK_230880.1	Both
LTRL590_050007100 ⚠ dual specificity phosphatase-like protein	—	OG6 LdBPK_050220.1 ↔ LdBPK_230880.1	OG6
LTRL590_230015600 ⚠ acetyl-CoA synthetase, putative	—	OG6 LdBPK_230580.1 ↔ LdBPK_230880.1 OG7 LdBPK_230580.1 ↔ LdBPK_230880.1	Both
LTRL590_300036900 ⚠ hypothetical protein, conserved	—	OG6 LdBPK_230880.1 ↔ LdBPK_303370.1 OG7 LdBPK_230880.1 ↔ LdBPK_303370.1	Both
LTRL590_290016300 ⚠ 5-histidylcysteine sulfoxide synthase, putati	—	OG6 LdBPK_230580.1 ↔ LdBPK_291030.1 OG6 LdBPK_230880.1 ↔ LdBPK_291030.1 OG7 LdBPK_230580.1 ↔ LdBPK_291030.1 OG7 LdBPK_230880.1 ↔ LdBPK_291030.1	Both
LTRL590_230011300 ⚠ AMP-binding enzyme/AMP-binding enzyme C-termi	—	OG6 LdBPK_230580.1 ↔ LdBPK_230880.1 OG7 LdBPK_230580.1 ↔ LdBPK_230880.1	Both
LTRL590_320031700 ⚠ NOL1/NOP2/sun family, putative	—	OG6 LdBPK_230580.1 ↔ LdBPK_322580.1 OG6 LdBPK_230880.1 ↔ LdBPK_322580.1 OG7 LdBPK_230580.1 ↔ LdBPK_322580.1 OG7 LdBPK_230880.1 ↔ LdBPK_322580.1	Both
LTRL590_350047300 ⚠ kinetoplastid kinetochore protein 3, putative	—	OG6 LdBPK_230880.1 ↔ LdBPK_354110.1 OG7 LdBPK_230880.1 ↔ LdBPK_354110.1	Both
LTRL590_300043600 ⚠ Protein of unknown function (DUF3808), putati	—	OG6 LdBPK_230580.1 ↔ LdBPK_303750.1 OG6 LdBPK_230880.1 ↔ LdBPK_303750.1 OG7 LdBPK_230580.1 ↔ LdBPK_303750.1 OG7 LdBPK_230880.1 ↔ LdBPK_303750.1	Both
LTRL590_360083800 ⚠ elks delta-like protein	—	OG6 LdBPK_230580.1 ↔ LdBPK_367300.1 OG6 LdBPK_230880.1 ↔ LdBPK_367300.1 OG7 LdBPK_230580.1 ↔ LdBPK_367300.1 OG7 LdBPK_230880.1 ↔ LdBPK_367300.1	Both
LTRL590_330042100 ⚠ hypothetical protein, conserved	—	OG6 LdBPK_230880.1 ↔ LdBPK_333400.1 OG7 LdBPK_230880.1 ↔ LdBPK_333400.1	Both
LTRL590_260017200 ⚠ heat-shock protein hsp70, putative	—	OG6 TCSYLVIO_000046 ↔ TCSYLVIO_002194 OG7 TCSYLVIO_000046 ↔ TCSYLVIO_002194	Both
LTRL590_280018200 ⚠ Hsp70 protein, putative	—	OG6 TCSYLVIO_000046 ↔ TCSYLVIO_002194 OG7 TCSYLVIO_000046 ↔ TCSYLVIO_002194	Both
LTRL590_280035400 ⚠ Hsp70 protein, putative	—	OG6 TCSYLVIO_000046 ↔ TCSYLVIO_002194 OG7 TCSYLVIO_000046 ↔ TCSYLVIO_002194	Both
LTRL590_280018100 ⚠ heat-shock protein hsp70, putative	—	OG6 TCSYLVIO_000046 ↔ TCSYLVIO_002194 OG7 TCSYLVIO_000046 ↔ TCSYLVIO_002194	Both
LTRL590_270025900 ⚠ trypanothione synthetase, putative	—	OG6 TCSYLVIO_000046 ↔ TCSYLVIO_000427 OG7 TCSYLVIO_000046 ↔ TCSYLVIO_000427	Both
LTRL590_090013900 ⚠ Uncharacterised protein family (UPF0160), put	—	OG6 TCSYLVIO_000046 ↔ TCSYLVIO_006555 OG7 TCSYLVIO_000046 ↔ TCSYLVIO_006555	Both
LTRL590_280035700 ⚠ heat-shock protein hsp70, putative	—	OG6 TCSYLVIO_000046 ↔ TCSYLVIO_002194	OG6
LTRL590_270025700 ⚠ paraflagellar rod protein-like protein	—	OG6 TCSYLVIO_000046 ↔ TCSYLVIO_000425 OG7 TCSYLVIO_000046 ↔ TCSYLVIO_000425	Both
LTRL590_240013400 ⚠ malic enzyme, putative	—	OG6 TCSYLVIO_000046 ↔ TCSYLVIO_001501 OG7 TCSYLVIO_000046 ↔ TCSYLVIO_001501	Both
LTRL590_260013000 ⚠ aspartate--ammonia ligase, putative	—	OG6 TCSYLVIO_000046 ↔ TCSYLVIO_002332 OG7 TCSYLVIO_000046 ↔ TCSYLVIO_002332	Both
LTRL590_290014800 ⚠ guanine deaminase, putative	—	OG6 TCSYLVIO_000046 ↔ TCSYLVIO_007737 OG7 TCSYLVIO_000046 ↔ TCSYLVIO_007737	Both