LTRL590_360038700

succinyl-CoA ligase [GDP-forming] beta-chain, putative
Leishmania tropica L590 OG6: OG6_100409 OG7: OG7_0003652 63 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 63 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LTRL590_250028800 ⚠
succinyl-CoA synthetase alpha subunit, putati
— +2 more Both
LTRL590_250028700 ⚠
succinyl-CoA synthetase alpha subunit, putati
— +2 more Both
LTRL590_280020100 ⚠
haloacid dehalogenase-like hydrolase, putativ
— Both
LTRL590_220008200 ⚠
carnitine palmitoyltransferase-like protein
— OG7
LTRL590_340006500 ⚠
malate dehydrogenase, putative
— OG7
LTRL590_340006200 ⚠
malate dehydrogenase, putative
— OG7
LTRL590_190011900 ⚠
glycosomal malate dehydrogenase
— OG7
LTRL590_060016200
deoxyribose-phosphate aldolase, putative
— Both
LTRL590_340043400
phosphomannomutase-like protein
— Both
LTRL590_350013100 ⚠
aspartate aminotransferase, putative
— Both
LTRL590_200006200 ⚠
Phosphoglycerate kinase, putative
— OG7
LTRL590_240009000 ⚠
aspartate aminotransferase, putative
— Both
LTRL590_280019600 ⚠
haloacid dehalogenase-like hydrolase, putativ
— Both
LTRL590_300009400
phosphatase 2C, putative
— OG6
LTRL590_290020100 ⚠
carnitine/choline acetyltransferase, putative
— Both
LTRL590_210015100 ⚠
hypoxanthine-guanine phosphoribosyltransferas
— Both
LTRL590_210015200 ⚠
xanthine phosphoribosyltransferase
— Both
LTRL590_240014300
triosephosphate isomerase
— Both
LTRL590_190019800 ⚠
choline/Carnitine o-acyltransferase-like prot
— OG7
LTRL590_240013500 ⚠
malic enzyme, putative
— Both
LTRL590_280019900 ⚠
hypothetical protein
— OG7
LTRL590_280019700 ⚠
haloacid dehalogenase-like hydrolase, putativ
— OG7
LTRL590_280019800 ⚠
haloacid dehalogenase-like hydrolase-like pro
— OG7
LTRL590_280020000 ⚠
haloacid dehalogenase-like hydrolase-like pro
— OG7
LTRL590_280020200 ⚠
haloacid dehalogenase-like hydrolase-like pro
— OG7
LTRL590_340042900 ⚠
serine palmitoyltransferase-like protein
— OG7
LTRL590_350008300 ⚠
serine palmitoyltransferase, putative
— OG7
LTRL590_130014900 ⚠
NADH-cytochrome b5 reductase, putative
— OG7
LTRL590_320030700 ⚠
cytochrome-b5 reductase, putative
— OG7
LTRL590_270012700 ⚠
reductase, putative
— OG7
LTRL590_110008000 ⚠
NADH-cytochrome b5 reductase-like protein
— OG7
LTRL590_320044900 ⚠
3-hydroxyisobutyryl-coenzyme a hydrolase-like
— OG7
LTRL590_150007700 ⚠
sterol carrier protein, putative
— OG7
LTRL590_340006400 ⚠
lactate/malate dehydrogenase, alpha/beta C-te
— Both
LTRL590_050012800
methylthioadenosine phosphorylase, putative
— Both
LTRL590_280030000
hd phosphohydrolase family protein
— Both
LTRL590_000022500
mitogen-activated protein kinase, putative
— OG6
LTRL590_350005200 ⚠
pyruvate kinase
— Both
LTRL590_320041600
dihydrolipoamide dehydrogenase, putative
— Both
LTRL590_300036100 ⚠
PAS-domain containing phosphoglycerate kinase
— Both
LTRL590_320005700
N-myristoyl transferase, putative
— Both
LTRL590_350005300 ⚠
pyruvate kinase
— Both
LTRL590_200006100 ⚠
Phosphoglycerate kinase, putative
— Both
LTRL590_360050600
hs1vu complex proteolytic subunit-like, threo
— Both
LTRL590_200006000 ⚠
Phosphoglycerate kinase, putative
— Both
LTRL590_340023100
pyroglutamyl-peptidase I (C15 family)
— Both
LTRL590_220006100
glutamine amidotransferase, putative
— Both
LTRL590_340006300 ⚠
lactate/malate dehydrogenase, NAD binding dom
— Both
LTRL590_230015400 ⚠
3-ketoacyl-CoA thiolase, putative
— Both
LTRL590_340006600 ⚠
malate dehydrogenase
— Both
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Orthogroup expansion — connections between the query proteins
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How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.