LTRL590_350036600

ubiquitin-activating enzyme E1, putative
Leishmania tropica L590 OG6: OG6_100444 OG7: OG7_0003530 176 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 176 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LTRL590_150018900 ⚠
ubiquitin hydrolase, putative
— OG7
LTRL590_340046700 ⚠
ubiquitin hydrolase, putative
— Both
LTRL590_350022600 ⚠
ubiquitin hydrolase, putative
— OG7
LTRL590_360054700 ⚠
ubiquitin protein ligase, putative
— OG7
LTRL590_030013200 ⚠
Leucine rich repeat/Ubiquitin-like domain con
— Both
LTRL590_350028400 ⚠
hypothetical protein, conserved
— Both
LTRL590_210012400 ⚠
nucleotide-binding protein, putative
— Both
LTRL590_280032300 ⚠
MRP protein-like protein
— OG6
LTRL590_260008900 ⚠
nucleotide binding protein-like protein
— Both
LTRL590_130011700 ⚠
protein kinase, putative
— Both
LTRL590_330009000 ⚠
ATP-binding cassette sub-family F member 1, p
— Both
LTRL590_020008600 ⚠
casein kinase II, alpha chain, putative
— OG6
LTRL590_160008400 ⚠
Met-10+ like-protein, putative
— Both
LTRL590_200011100 ⚠
hypothetical protein, conserved
— Both
LTRL590_340048200 ⚠
hypothetical protein, conserved
— Both
LTRL590_350012300 ⚠
proteasome activator protein pa26, putative
— Both
LTRL590_050007200 ⚠
hydrogenase, putative
— Both
LTRL590_210017000 ⚠
Programmed cell death protein 2, C-terminal p
— Both
LTRL590_000020200 ⚠
Metallo-beta-lactamase superfamily, putative
— Both
LTRL590_220015400 ⚠
hypothetical protein, conserved
— Both
LTRL590_220015300 ⚠
Beta-lactamase superfamily domain containing
— Both
LTRL590_000020100 ⚠
hypothetical protein
— Both
LTRL590_020005000 ⚠
metallo-peptidase, Clan MG, Family M24
— Both
LTRL590_030012900 ⚠
TatD related DNase, putative
— Both
LTRL590_070013800 ⚠
HEAT-like repeat, putative
— OG7
LTRL590_070013500 ⚠
HEAT-like repeat, putative
— OG7
LTRL590_100006400 ⚠
zinc-binding dehydrogenase-like protein
— OG7
LTRL590_170007900 ⚠
Dihydrouridine synthase (Dus), putative
— OG7
LTRL590_160009300 ⚠
XRN 5'-3' exonuclease N-terminus, putative
— OG7
LTRL590_360010000 ⚠
dihydrouridine synthase domain protein-like p
— OG7
LTRL590_330007200 ⚠
metallo-peptidase, Clan MC, Family M14, putat
— OG7
LTRL590_340018100 ⚠
Dihydrouridine synthase (Dus), putative
— OG7
LTRL590_220019100 ⚠
Mitochondrial glycoprotein, putative
— OG7
LTRL590_260012200 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LTRL590_260012100 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LTRL590_290026700 ⚠
hypothetical protein, conserved
— OG7
LTRL590_030012300 ⚠
DEAD/DEAH box helicase, putative
— OG7
LTRL590_320029300 ⚠
small nuclear ribonucleoprotein component-lik
— OG7
LTRL590_000012300 ⚠
elongation factor 2
— OG7
LTRL590_050012400 ⚠
Mitochondrial glycoprotein, putative
— OG7
LTRL590_260026200 ⚠
hypothetical protein, conserved
— OG7
LTRL590_320017400 ⚠
HECT-domain (ubiquitin-transferase), putative
— OG7
LTRL590_110010100 ⚠
chromatin binding protein, putative
— OG7
LTRL590_360007100 ⚠
Elongation factor G C-terminus, putative
— OG7
LTRL590_170006800 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LTRL590_320022500 ⚠
Putative GTPase activating protein for Arf, p
— OG7
LTRL590_210017600 ⚠
epsilon tubulin, putative
— OG7
LTRL590_280024600 ⚠
Putative GTPase activating protein for Arf, p
— OG7
LTRL590_360061500 ⚠
delta tubulin, putative
— OG7
LTRL590_220009800 ⚠
Putative tRNA binding domain containing prote
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.