LbrM.18.1700

gamma-glutamylcysteine synthetase, putative
Leishmania braziliensis MHOM/BR/75/M2904 OG6: OG6_102076 OG7: OG7_0007073 19 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Network view all shared interactors, plus up to 150 more
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Interactions 19 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LbrM.05.0970 ⚠
3-mercaptopyruvate sulfurtransferase
— Both
LbrM.24.1810 ⚠
SET domain containing protein, putative
— OG7
LbrM.35.7140 ⚠
hypothetical protein
— OG7
LbrM.27.0170 ⚠
SET domain containing protein, putative
— OG7
LbrM.06.0980 ⚠
SET domain containing protein, putative
— OG7
LbrM.23.0880 ⚠
SET domain containing protein, putative
— OG7
LbrM.33.0500 ⚠
SET domain containing protein, putative
— OG7
LbrM.20.1020 ⚠
TPR repeat/SET domain containing protein, put
— OG7
LbrM.10.1480 ⚠
SET domain containing protein, putative
— OG7
LbrM.20.6030 ⚠
SET domain containing protein, putative
— OG7
LbrM.23.0910 ⚠
SET domain containing protein, putative
— Both
LbrM.05.0950 ⚠
3-mercaptopyruvate sulfurtransferase (fragmen
— Both
LbrM.22.1130
hypothetical protein, conserved
— Both
LbrM.14.1320 ⚠
enolase
— Both
LbrM.14.1330 ⚠
enolase
— Both
LbrM.34.4450 ⚠
Co-chaperone protein P23
— Both
LbrM.20.0220 ⚠
CS domain containing protein, putative
— Both
LbrM.29.2850
inosine-adenosine-guanosine-nucleosidehydrola
— Both
LbrM.35.7010
2,3-bisphosphoglycerate-independent phosphogl
— Both
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.