LbrM.14.1320

enolase
Leishmania braziliensis MHOM/BR/75/M2904 OG6: OG6_100260 OG7: OG7_0002539 43 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 43 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LbrM.18.1700 ⚠
gamma-glutamylcysteine synthetase, putative
— Both
LbrM.14.1300 ⚠
D-isomer specific 2-hydroxyacid dehydrogenase
— +2 more Both
LbrM.20.1430 ⚠
d-isomer specific 2-hydroxyacid dehydrogenase
— +2 more Both
LbrM.18.0570 ⚠
aconitase, putative
— Both
LbrM.05.0350 ⚠
trypanothione reductase
— Both
LbrM.29.2540 ⚠
serine/threonine-protein kinase, putative
— OG6
LbrM.24.2140 ⚠
transketolase
— Both
LbrM.20.0220 ⚠
CS domain containing protein, putative
— Both
LbrM.35.2180 ⚠
phosphomannomutase, putative
— Both
LbrM.35.7010 ⚠
2,3-bisphosphoglycerate-independent phosphogl
— Both
LbrM.34.4450 ⚠
Co-chaperone protein P23
— Both
LbrM.35.0270 ⚠
elongation factor 2
— Both
LbrM.12.0630 ⚠
alanine aminotransferase
— Both
LbrM.05.0950 ⚠
3-mercaptopyruvate sulfurtransferase (fragmen
— Both
LbrM.05.0970 ⚠
3-mercaptopyruvate sulfurtransferase
— Both
LbrM.22.0310 ⚠
SEP domain containing protein, putative
— Both
LbrM.20.4800 ⚠
cytidine triphosphate synthase, putative, CTP
— Both
LbrM.26.0330 ⚠
metallo-peptidase, Clan MA(E), Family M1
— OG7
LbrM.12.0930 ⚠
puromycin-sensitive aminopeptidase-like prote
— OG7
LbrM.32.2420 ⚠
U5 small nuclear ribonucleoprotein component,
— OG7
LbrM.25.1640 ⚠
elongation factor 2-like protein
— OG7
LbrM.15.0270 ⚠
sterol carrier protein, putative, nonspecific
— OG7
LbrM.32.3210 ⚠
nucleoside diphosphate kinase b
— Both
LbrM.18.0760 ⚠
citrate synthase, putative
— Both
LbrM.24.0790 ⚠
malic enzyme, putative
— Both
LbrM.29.2220 ⚠
Aminopeptidase M1, putative
— Both
LbrM.29.2120 ⚠
C-8 sterol isomerase-like protein
— Both
LbrM.23.0840 ⚠
3-ketoacyl-CoA thiolase, putative
— Both
LbrM.29.1930 ⚠
Fumarate hydratase class I, cytosolic
— Both
LbrM.26.0840 ⚠
aspartate--ammonia ligase, putative, asparagi
— Both
LbrM.05.0800 ⚠
methylthioadenosine phosphorylase, putative
— Both
LbrM.16.0560 ⚠
aspartate carbamoyltransferase, putative
— Both
LbrM.24.2190 ⚠
3-hydroxy-3-methylglutaryl-CoA synthase, puta
— Both
LbrM.18.0770 ⚠
citrate synthase, putative
— Both
LbrM.24.0780 ⚠
malic enzyme
— Both
LbrM.26.2160 ⚠
kynureninase, putative
— Both
LbrM.35.0260 ⚠
elongation factor 2
— Both
LbrM.34.3250 ⚠
6-phosphogluconate dehydrogenase, decarboxyla
— Both
LbrM.24.0320 ⚠
fumarate hydratase, putative
— Both
LbrM.10.0310 ⚠
isocitrate dehydrogenase [NADP], mitochondria
— Both
LbrM.32.3200 ⚠
nucleoside diphosphate kinase b
— Both
LbrM.35.0250 ⚠
elongation factor 2
— Both
LbrM.34.2990 ⚠
glycerol kinase, glycosomal, putative
— Both
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.