LbrM.24.2190

3-hydroxy-3-methylglutaryl-CoA synthase, putative
Leishmania braziliensis MHOM/BR/75/M2904 OG6: OG6_101064 OG7: OG7_0006553 86 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 86 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LbrM.23.0050 ⚠
Peroxiredoxin PRX1M
— Both
LbrM.28.2190 ⚠
protein lipid droplet kinase (LDK)
— OG7
LbrM.29.1990 ⚠
5'-AMP-activated protein kinase catalytic sub
— OG7
LbrM.01.0740 ⚠
Eukaryotic initiation factor 4A-1
— OG7
LbrM.21.0210 ⚠
serine/threonine-protein kinase-like protein
— OG7
LbrM.12.0930 ⚠
puromycin-sensitive aminopeptidase-like prote
— OG7
LbrM.26.0330 ⚠
metallo-peptidase, Clan MA(E), Family M1
— OG7
LbrM.30.2540 ⚠
hypothetical protein, conserved
— OG7
LbrM.34.2090 ⚠
adenine aminohydrolase
— OG7
LbrM.15.0270 ⚠
sterol carrier protein, putative, nonspecific
— OG7
LbrM.20.4800
cytidine triphosphate synthase, putative, CTP
— Both
LbrM.22.0750 ⚠
protein kinase, putative, serine/threonine pr
— OG7
LbrM.15.1100 ⚠
tryparedoxin peroxidase
— Both
LbrM.15.1080 ⚠
Peroxiredoxin PRX1A
— Both
LbrM.23.0840 ⚠
3-ketoacyl-CoA thiolase, putative
— Both
LbrM.24.0320 ⚠
fumarate hydratase, putative
— Both
LbrM.29.1930 ⚠
Fumarate hydratase class I, cytosolic
— Both
LbrM.32.3200 ⚠
nucleoside diphosphate kinase b
— Both
LbrM.32.3210 ⚠
nucleoside diphosphate kinase b
— Both
LbrM.10.0940 ⚠
hypothetical protein, conserved
— Both
LbrM.17.0230 ⚠
cystathionine beta-synthase (fragment)
— Both
LbrM.35.3820 ⚠
cysteine synthase
— OG6
LbrM.29.2370 ⚠
NLI interacting factor-like phosphatase, puta
— OG7
LbrM.25.1640 ⚠
elongation factor 2-like protein
— OG7
LbrM.32.2420 ⚠
U5 small nuclear ribonucleoprotein component,
— OG7
LbrM.32.0160 ⚠
NLI interacting factor-like phosphatase, puta
— OG7
LbrM.31.0300 ⚠
nucleolar protein, putative
— OG7
LbrM.32.2670 ⚠
NOL1/NOP2/sun family, putative
— OG7
LbrM.34.2540 ⚠
TFIIF-stimulated CTD phosphatase, putative
— OG7
LbrM.34.3450 ⚠
NLI interacting factor-like phosphatase, puta
— OG7
LbrM.35.7130 ⚠
nuclear lim interactor-interacting factor, pu
— OG7
LbrM.27.1560 ⚠
choline kinase, ethanolamine kinase, putative
— OG7
LbrM.25.1590 ⚠
dullard-like phosphatase domain containing pr
— OG7
LbrM.24.1790 ⚠
protein kinase, putative, calcium/calmodulin-
— Both
LbrM.29.1970 ⚠
hypothetical protein, conserved
— OG7
LbrM.26.0150 ⚠
nuclear lim interactor-interacting factor-lik
— OG7
LbrM.34.0230 ⚠
NLI interacting factor-like phosphatase, puta
— OG7
LbrM.28.1910 ⚠
NOL1/NOP2/sun family, putative
— OG7
LbrM.19.0070 ⚠
serine/threonine protein kinase, putative
— OG7
LbrM.34.2270 ⚠
protein kinase, putative
— OG7
LbrM.33.1980 ⚠
protein kinase, putative
— OG7
LbrM.28.1700 ⚠
ATP-dependent RNA helicase FAL1, putative
— OG7
LbrM.35.1020 ⚠
SNF1-related protein kinases, putative
— OG7
LbrM.10.0860
hypothetical protein, conserved
— Both
LbrM.21.1700 ⚠
ATP-dependent RNA helicase SUB2, putative
— Both
LbrM.18.0720 ⚠
serine/threonine kinase-like protein, putativ
— Both
LbrM.07.0960 ⚠
protein kinase, putative, serine/threonine ki
— Both
LbrM.35.3170
succinyl-CoA ligase [GDP-forming] beta-chain,
— Both
LbrM.16.0560
aspartate carbamoyltransferase, putative
— Both
LbrM.21.0790 ⚠
hypothetical protein, conserved
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.