LbrM.29.1990

5'-AMP-activated protein kinase catalytic subunit alpha, putative
Leishmania braziliensis MHOM/BR/75/M2904 OG6: OG6_100252 OG7: OG7_0000009 171 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 171 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LbrM.34.5000 ⚠
hypothetical protein, conserved
— +1 more Both
LbrM.29.2080 ⚠
Present in the outer mitochondrial membrane p
— OG7
LbrM.33.1980 ⚠
protein kinase, putative
— OG7
LbrM.32.1000 ⚠
Alpha/beta hydrolase family, putative
— OG7
LbrM.31.0140 ⚠
ubiquitin carboxyl-terminal hydrolase, putati
— OG7
LbrM.29.1390 ⚠
carnitine/choline acetyltransferase, putative
— OG7
LbrM.22.0300 ⚠
carnitine palmitoyltransferase-like protein
— OG7
LbrM.19.1800 ⚠
choline/Carnitine o-acyltransferase-like prot
— OG7
LbrM.28.0210 ⚠
hypothetical protein, conserved
— OG7
LbrM.25.1070 ⚠
TAP42-like family, putative
— OG7
LbrM.32.2630 ⚠
hypothetical protein, conserved
— OG7
LbrM.20.3380 ⚠
phosphomannomutase-like protein
— OG7
LbrM.16.0750 ⚠
transaldolase, putative
— OG7
LbrM.28.2160 ⚠
Elongation factor G 2, mitochondrial, putativ
— OG7
LbrM.35.0680 ⚠
Elongation factor G1, mitochondrial, putative
— OG7
LbrM.34.0010 ⚠
pyruvate kinase
— OG7
LbrM.34.0070 ⚠
pyruvate kinase, putative (fragment)
— OG7
LbrM.34.0060 ⚠
pyruvate kinase
— OG7
LbrM.34.0040 ⚠
pyruvate kinase
— OG7
LbrM.28.1530 ⚠
hypothetical protein, conserved
— OG7
LbrM.28.1520 ⚠
haloacid dehalogenase-like hydrolase, putativ
— OG7
LbrM.28.1490 ⚠
haloacid dehalogenase-like hydrolase-like pro
— OG7
LbrM.25.0910 ⚠
dehydrogenase-like protein
— OG7
LbrM.03.0820 ⚠
inorganic pyrophosphatase, putative
— OG7
LbrM.30.0180 ⚠
2-hydroxy-3-oxopropionate reductase, putative
— OG7
LbrM.28.1510 ⚠
haloacid dehalogenase-like hydrolase-like pro
— OG7
LbrM.28.1440 ⚠
hypothetical protein, conserved
— OG7
LbrM.28.1480 ⚠
hypothetical protein, conserved
— OG7
LbrM.19.0110 ⚠
acidocalcisomal pyrophosphatase
— OG7
LbrM.34.4160 ⚠
Protein of unknown function (DUF2009), putati
— OG7
LbrM.17.1260 ⚠
5'-3' exoribonuclease B, putative
— OG7
LbrM.35.3810 ⚠
Protein of unknown function (DUF2009), putati
— OG7
LbrM.35.1980 ⚠
5'-3' exoribonuclease D, putative
— OG7
LbrM.06.0240 ⚠
5'-3' exoribonuclease A, putative
— OG7
LbrM.30.0740 ⚠
pdz domain containing protein, putative
— OG7
LbrM.26.2630 ⚠
6-phosphogluconolactonase
— OG7
LbrM.26.2660 ⚠
6-phosphogluconolactonase
— OG7
LbrM.35.4740 ⚠
Protein of unknown function (DUF2870), putati
— OG7
LbrM.16.1550 ⚠
hypothetical protein, conserved
— OG7
LbrM.22.0110 ⚠
GMP synthase [glutamine-hydrolysing]
— OG7
LbrM.18.0230 ⚠
Activator of Hsp90 ATPase, N-terminal/Activat
— OG7
LbrM.28.2260 ⚠
tRNA threonylcarbamoyl adenosine modification
— OG7
LbrM.30.1050 ⚠
hypothetical protein, conserved
— OG7
LbrM.24.0370 ⚠
aspartate aminotransferase, putative
— OG7
LbrM.28.1190 ⚠
WD domain, G-beta repeat, putative
— OG7
LbrM.25.1570 ⚠
2,4-dihydroxyhept-2-ene-1,7-dioic acid aldola
— OG7
LbrM.21.0070 ⚠
hypothetical protein, conserved
— OG7
LbrM.21.0060 ⚠
hypothetical protein, conserved
— OG7
LbrM.18.0030 ⚠
mevalonate-diphosphate decarboxylase, putativ
— OG7
LbrM.32.2690 ⚠
Cid1 family poly A polymerase, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.