LbrM.34.0070

pyruvate kinase, putative (fragment)
Leishmania braziliensis MHOM/BR/75/M2904 OG6: OG6_100258 OG7: OG7_0002165 184 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 184 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LbrM.03.0820 ⚠
inorganic pyrophosphatase, putative
— Both
LbrM.19.0110 ⚠
acidocalcisomal pyrophosphatase
— Both
LbrM.14.1360 ⚠
Bifunctional NAD(P)H-hydrate repair enzyme
— Both
LbrM.33.2840 ⚠
metallo-peptidase, Clan MF, Family M17
— OG7
LbrM.30.2950 ⚠
glyceraldehyde 3-phosphate dehydrogenase, gly
— Both
LbrM.04.0490 ⚠
cysteine peptidase, Clan CA, family C2, putat
— OG6
LbrM.18.1610 ⚠
nonspecific nucleoside hydrolase
— Both
LbrM.01.0550 ⚠
long-chain-fatty-acid-CoA ligase, putative (f
— Both
LbrM.01.0540 ⚠
long-chain-fatty-acid-CoA ligase, putative
— Both
LbrM.34.0820 ⚠
NADH-dependent fumarate reductase-like protei
— Both
LbrM.34.1110 ⚠
NADH-dependent fumarate reductase, putative
— Both
LbrM.30.3550 ⚠
S-adenosylmethionine synthetase
— Both
LbrM.30.1610 ⚠
pseudouridine synthase A-like protein, putati
— Both
LbrM.27.1010 ⚠
isovaleryl-coA dehydrogenase, putative
— Both
LbrM.20.5390 ⚠
calpain-like cysteine peptidase, putative, cy
— OG6
LbrM.20.5340 ⚠
cysteine peptidase, Clan CA, family C2, putat
— OG6
LbrM.15.1480 ⚠
cAMP specific phosphodiesterase, putative
— Both
LbrM.11.0410 ⚠
metallo-peptidase, Clan MF, Family M17
— Both
LbrM.34.1090 ⚠
NADH-dependent fumarate reductase, putative
— Both
LbrM.20.2970 ⚠
aldose 1-epimerase-like protein
— Both
LbrM.34.1100 ⚠
NADH-dependent fumarate reductase, putative
— Both
LbrM.34.4710 ⚠
glyceraldehyde-3-phosphate dehydrogenase-like
— Both
LbrM.06.0830 ⚠
dihydrofolate reductase-thymidylate synthase
— Both
LbrM.15.1430 ⚠
glutaminyl-tRNA synthetase, putative
— Both
LbrM.15.1250 ⚠
cAMP specific phosphodiesterase, putative
— Both
LbrM.30.0420 ⚠
phosphatase 2C, putative
— OG6
LbrM.28.1220 ⚠
electron-transfer-flavoprotein, alpha polypep
— Both
LbrM.23.1720 ⚠
alanine racemase, putative
— Both
LbrM.22.0310 ⚠
SEP domain containing protein, putative
— Both
LbrM.20.3380 ⚠
phosphomannomutase-like protein
— Both
LbrM.20.5930 ⚠
amidohydrolase, putative
— Both
LbrM.30.1491 ⚠
N-acyl-L-amino acid amidohydrolase, putative
— Both
LbrM.20.5920 ⚠
amidohydrolase, putative
— Both
LbrM.20.5910 ⚠
amidohydrolase, putative
— Both
LbrM.31.1330 ⚠
amidohydrolase, putative
— Both
LbrM.28.2260 ⚠
tRNA threonylcarbamoyl adenosine modification
— Both
LbrM.32.0130 ⚠
N-myristoyl transferase, putative
— Both
LbrM.01.0250 ⚠
cyclophilin 12, putative
— OG6
LbrM.31.0140 ⚠
ubiquitin carboxyl-terminal hydrolase, putati
— Both
LbrM.33.1160 ⚠
nicotinate phosphoribosyltransferase, putativ
— Both
LbrM.33.3090 ⚠
transcription elongation factor-like protein
— Both
LbrM.12.0490 ⚠
glucose-6-phosphate isomerase
— Both
LbrM.27.0800 ⚠
UBA/TS-N domain containing protein, putative
— Both
LbrM.06.1050 ⚠
deoxyribose-phosphate aldolase, putative
— Both
LbrM.13.0120 ⚠
Kinesin-13 2, putative
— OG7
LbrM.31.0400 ⚠
Kinesin-13 4, putative
— OG7
LbrM.01.0060 ⚠
Kinesin-13 1, putative
— OG7
LbrM.28.1530 ⚠
hypothetical protein, conserved
— OG7
LbrM.35.1020 ⚠
SNF1-related protein kinases, putative
— OG7
LbrM.33.1980 ⚠
protein kinase, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.