LbrM.27.1010

isovaleryl-coA dehydrogenase, putative
Leishmania braziliensis MHOM/BR/75/M2904 OG6: OG6_102105 OG7: OG7_0001034 41 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 41 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LbrM.12.0490
glucose-6-phosphate isomerase
— Both
LbrM.33.2630 ⚠
succinyl-coA:3-ketoacid-coenzyme A transferas
— Both
LbrM.34.4710 ⚠
glyceraldehyde-3-phosphate dehydrogenase-like
— Both
LbrM.15.1430 ⚠
glutaminyl-tRNA synthetase, putative
— Both
LbrM.30.1870 ⚠
succinyl-coa:3-ketoacid-coenzyme a transferas
— Both
LbrM.35.1950
aldehyde dehydrogenase, putative
— Both
LbrM.20.0160
glucose-6-phosphate 1-dehydrogenase, putative
— Both
LbrM.34.0010 ⚠
pyruvate kinase
— Both
LbrM.34.0070 ⚠
pyruvate kinase, putative (fragment)
— Both
LbrM.34.0060 ⚠
pyruvate kinase
— Both
LbrM.34.0040 ⚠
pyruvate kinase
— Both
LbrM.20.2970
aldose 1-epimerase-like protein
— Both
LbrM.35.1280 ⚠
endonuclease/exonuclease/phosphatase, putativ
— OG7
LbrM.15.1160 ⚠
inositol/phosphatidylinositol phosphatase, pu
— OG7
LbrM.15.1020
DNA repair protein Rad9, putative
— OG7
LbrM.34.4210 ⚠
hypothetical protein, conserved
— OG7
LbrM.24.0840 ⚠
inositol polyphosphate phosphatase, putative
— OG7
LbrM.30.2950 ⚠
glyceraldehyde 3-phosphate dehydrogenase, gly
— OG7
LbrM.30.3280 ⚠
glutamyl-tRNA synthetase, putative
— OG7
LbrM.01.0560 ⚠
long-chain-fatty-acid-CoA ligase, putative
— OG7
LbrM.01.0260 ⚠
long-chain-fatty-acid-CoA ligase, putative (f
— OG7
LbrM.30.1810 ⚠
succinyl-coa:3-ketoacid-coenzyme a transferas
— Both
LbrM.15.1080 ⚠
Peroxiredoxin PRX1A
— Both
LbrM.15.1100 ⚠
tryparedoxin peroxidase
— Both
LbrM.14.0130 ⚠
inosine-guanine nucleoside hydrolase, putativ
— Both
LbrM.24.2140
transketolase
— Both
LbrM.03.0240 ⚠
long chain fatty Acyl CoA synthetase, putativ
— Both
LbrM.29.0910
guanine deaminase, putative
— Both
LbrM.32.3550
glucosamine-6-phosphate isomerase, putative
— Both
LbrM.11.0800
pyruvate phosphate dikinase, putative
— Both
LbrM.01.0520 ⚠
fatty acyl CoA syntetase 1, putative
— Both
LbrM.20.2310
hypothetical protein, conserved
— Both
LbrM.13.0970
adenylosuccinate synthetase, putative
— Both
LbrM.06.0350
glutamine synthetase, putative
— Both
LbrM.18.1610 ⚠
nonspecific nucleoside hydrolase
— Both
LbrM.01.0550 ⚠
long-chain-fatty-acid-CoA ligase, putative (f
— Both
LbrM.01.0540 ⚠
long-chain-fatty-acid-CoA ligase, putative
— Both
LbrM.23.0120
GDP-mannose pyrophosphorylase
— Both
LbrM.26.0050
glycine dehydrogenase, putative
— Both
LbrM.30.3550
S-adenosylmethionine synthetase
— Both
LbrM.23.0050 ⚠
Peroxiredoxin PRX1M
— Both
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.