LbrM.01.0560

long-chain-fatty-acid-CoA ligase, putative
Leishmania braziliensis MHOM/BR/75/M2904 OG6: OG6_478831 OG7: OG7_0001203 57 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 57 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LbrM.26.0910 ⚠
chaperone protein-like protein, heat shock 70
— OG7
LbrM.32.4210 ⚠
cAMP response protein 1, putative
— OG7
LbrM.29.0780 ⚠
heat shock protein 90, putative
— OG7
LbrM.25.0950 ⚠
hypothetical protein, conserved
— OG7
LbrM.13.0150 ⚠
protein kinase A regulatory subunit
— OG7
LbrM.32.3300 ⚠
hypothetical protein, conserved, leucine-rich
— OG7
LbrM.33.0340 ⚠
heat shock protein 83, heat shock protein 83-
— OG7
LbrM.05.0180 ⚠
dihydrolipoamide branched chain transacylase,
— OG7
LbrM.20.2170 ⚠
ruvB-like DNA helicase, putative
— OG7
LbrM.33.0330 ⚠
heat shock protein 83-1
— OG7
LbrM.20.2440 ⚠
regulatory subunit of protein kinase a-like p
— OG7
LbrM.20.3080 ⚠
ruvb-like 1 DNA helicase, putative
— OG7
LbrM.21.1980 ⚠
centromere/microtubule binding protein cbf5,
— OG7
LbrM.12.0490 ⚠
glucose-6-phosphate isomerase
— OG7
LbrM.26.1260 ⚠
heat shock protein 70-related protein
— OG7
LbrM.33.0350 ⚠
heat shock protein 83-1
— OG7
LbrM.01.0790 ⚠
HSP70-like protein
— OG7
LbrM.28.2980 ⚠
heat-shock protein hsp70, putative (fragment)
— OG7
LbrM.28.1300 ⚠
luminal binding protein 1 (BiP), putative
— OG7
LbrM.28.2990 ⚠
heat-shock protein hsp70, putative
— OG7
LbrM.34.4680 ⚠
Hsp70 protein, putative
— OG7
LbrM.18.1400 ⚠
heat shock protein 110, putative
— OG7
LbrM.28.2970 ⚠
heat-shock protein hsp70, putative
— OG7
LbrM.27.2210 ⚠
branched-chain amino acid aminotransferase, p
— OG7
LbrM.14.0130 ⚠
inosine-guanine nucleoside hydrolase, putativ
— OG7
LbrM.18.1610 ⚠
nonspecific nucleoside hydrolase
— OG7
LbrM.29.0760 ⚠
peroxisomal targeting signal 2 receptor, puta
— OG7
LbrM.11.0880 ⚠
Lanosterol 14-alpha demethylase
— OG7
LbrM.13.0970 ⚠
adenylosuccinate synthetase, putative
— OG7
LbrM.34.1800 ⚠
60S ribosomal protein L5, putative
— OG7
LbrM.34.0070 ⚠
pyruvate kinase, putative (fragment)
— OG7
LbrM.34.0060 ⚠
pyruvate kinase
— OG7
LbrM.34.0040 ⚠
pyruvate kinase
— OG7
LbrM.30.2950 ⚠
glyceraldehyde 3-phosphate dehydrogenase, gly
— OG7
LbrM.33.2880 ⚠
enoyl-CoA hydratase/Enoyl-CoA isomerase/3- hy
— OG7
LbrM.26.1570 ⚠
trifunctional enzyme alpha subunit, mitochond
— OG7
LbrM.30.3280 ⚠
glutamyl-tRNA synthetase, putative
— OG7
LbrM.34.4710 ⚠
glyceraldehyde-3-phosphate dehydrogenase-like
— OG7
LbrM.15.1430 ⚠
glutaminyl-tRNA synthetase, putative
— OG7
LbrM.04.0630 ⚠
spermidine synthase, putative
— OG7
LbrM.30.3550 ⚠
S-adenosylmethionine synthetase
— OG7
LbrM.14.0350 ⚠
threonine synthase, putative
— OG7
LbrM.24.2140 ⚠
transketolase
— OG7
LbrM.34.0010 ⚠
pyruvate kinase
— OG7
LbrM.34.1790 ⚠
60S ribosomal protein L5, putative
— OG7
LbrM.29.0910 ⚠
guanine deaminase, putative
— OG7
LbrM.26.1630 ⚠
Proline dehydrogenase, mitochondrial
— OG7
LbrM.33.3140 ⚠
cysteine peptidase, Clan CA, family C51, puta
— OG7
LbrM.27.2010 ⚠
trypanothione synthetase
— OG7
LbrM.23.0490 ⚠
trypanothione synthetase, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.