LbrM.20.3080

ruvb-like 1 DNA helicase, putative
Leishmania braziliensis MHOM/BR/75/M2904 OG6: OG6_101792 OG7: OG7_0003574 45 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 45 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LbrM.21.1980 ⚠
centromere/microtubule binding protein cbf5,
— +1 more Both
LbrM.21.2070 ⚠
centromere/microtubule binding protein cbf5,
— +1 more Both
LbrM.20.2170 ⚠
ruvB-like DNA helicase, putative
— Both
LbrM.13.0150 ⚠
protein kinase A regulatory subunit
— OG7
LbrM.20.0020 ⚠
malate dehydrogenase, putative
— OG7
LbrM.14.0960 ⚠
sodium/hydrogen exchanger, putative
— OG7
LbrM.31.1330 ⚠
amidohydrolase, putative
— OG7
LbrM.19.1020 ⚠
glycosomal malate dehydrogenase
— OG7
LbrM.05.0180 ⚠
dihydrolipoamide branched chain transacylase,
— OG7
LbrM.20.5920 ⚠
amidohydrolase, putative
— OG7
LbrM.20.5910 ⚠
amidohydrolase, putative
— OG7
LbrM.05.0350 ⚠
trypanothione reductase
— OG7
LbrM.15.1140 ⚠
protein kinase, putative
— OG7
LbrM.32.4210 ⚠
cAMP response protein 1, putative
— OG7
LbrM.30.1050 ⚠
hypothetical protein, conserved
— OG7
LbrM.29.2080 ⚠
Present in the outer mitochondrial membrane p
— OG7
LbrM.35.4230 ⚠
ATP-dependent protease subunit HslV, putative
— Both
LbrM.20.2440 ⚠
regulatory subunit of protein kinase a-like p
— OG7
LbrM.03.0240 ⚠
long chain fatty Acyl CoA synthetase, putativ
— OG7
LbrM.01.0520 ⚠
fatty acyl CoA syntetase 1, putative
— OG7
LbrM.01.0560 ⚠
long-chain-fatty-acid-CoA ligase, putative
— OG7
LbrM.01.0260 ⚠
long-chain-fatty-acid-CoA ligase, putative (f
— OG7
LbrM.01.0550 ⚠
long-chain-fatty-acid-CoA ligase, putative (f
— OG7
LbrM.01.0540 ⚠
long-chain-fatty-acid-CoA ligase, putative
— OG7
LbrM.29.1390 ⚠
carnitine/choline acetyltransferase, putative
— OG7
LbrM.18.1180 ⚠
protein kinase A catalytic subunit 3
— OG6
LbrM.34.3990 ⚠
protein kinase A catalytic subunit isoform 1
— OG6
LbrM.19.0410 ⚠
fibrillarin, putative
— Both
LbrM.35.3290 ⚠
fibrillarin
— Both
LbrM.30.3350 ⚠
MORN repeat-containing protein 1
— Both
LbrM.15.1050 ⚠
glutamate dehydrogenase
— Both
LbrM.13.0010 ⚠
hypothetical protein, conserved
— Both
LbrM.12.0270 ⚠
cysteinyl-tRNA synthetase, putative
— Both
LbrM.30.2270 ⚠
SET domain containing protein, putative
— Both
LbrM.32.0960 ⚠
phenylalanyl-tRNA synthetase alpha chain, put
— Both
LbrM.20.0010 ⚠
mitochondrial malate dehydrogenase
— OG7
LbrM.22.0300 ⚠
carnitine palmitoyltransferase-like protein
— OG7
LbrM.19.1800 ⚠
choline/Carnitine o-acyltransferase-like prot
— OG7
LbrM.35.7100 ⚠
prolyl endopeptidase
— OG7
LbrM.20.0040 ⚠
malate dehydrogenase, putative
— OG7
LbrM.20.5930 ⚠
amidohydrolase, putative
— OG7
LbrM.06.0320 ⚠
oligopeptidase B-like protein, serine peptida
— OG7
LbrM.09.0850 ⚠
oligopeptidase b
— OG7
LbrM.30.1491 ⚠
N-acyl-L-amino acid amidohydrolase, putative
— OG7
LbrM.20.0030 ⚠
malate dehydrogenase
— OG7
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.