LbrM.19.0410

fibrillarin, putative
Leishmania braziliensis MHOM/BR/75/M2904 OG6: OG6_100868 OG7: OG7_0005355 110 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 110 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LbrM.16.1170 ⚠
WW domain containing protein, putative
— OG7
LbrM.15.1380 ⚠
nucleolar RNA binding protein, putative
— +2 more Both
LbrM.07.0940 ⚠
splicing factor ptsr1-like protein
— Both
LbrM.20.3080 ⚠
ruvb-like 1 DNA helicase, putative
— Both
LbrM.35.3290 ⚠
fibrillarin
— Both
LbrM.35.1980 ⚠
5'-3' exoribonuclease D, putative
— Both
LbrM.06.0240 ⚠
5'-3' exoribonuclease A, putative
— Both
LbrM.07.0290 ⚠
ubiquitin-protein ligase-like, putative
— Both
LbrM.10.1160 ⚠
hypothetical protein, conserved
— Both
LbrM.04.0600 ⚠
TPR repeat/Tetratricopeptide repeat, putative
— Both
LbrM.20.6060 ⚠
arginine N-methyltransferase-like protein
— +2 more Both
LbrM.04.0070 ⚠
cAMP-specific phosphodiesterase, putative
— Both
LbrM.09.0880 ⚠
kinetoplast-associated protein-like protein
— OG6
LbrM.02.0130 ⚠
phosphatidylinositol kinase related protein,
— Both
LbrM.15.1240 ⚠
cysteine peptidase, Clan CA, family C19, puta
— Both
LbrM.04.0890 ⚠
axonemal dynein light chain, putative
— Both
LbrM.14.0900 ⚠
immunodominant antigen, putative, tc40 antige
— Both
LbrM.12.0020 ⚠
translation initiation factor EIF-2b alpha su
— Both
LbrM.04.0380 ⚠
hypothetical protein, conserved
— Both
LbrM.09.1270 ⚠
AAA family ATPase, putative
— Both
LbrM.27.1310 ⚠
translation initiation factor eIF2B delta sub
— OG7
LbrM.17.1240 ⚠
NOL1/NOP2/sun family, putative
— OG7
LbrM.35.2410 ⚠
NOL1/NOP2/sun family, putative
— OG7
LbrM.29.2510 ⚠
NOL1/NOP2/sun family, putative
— OG7
LbrM.20.1950 ⚠
Sec7 domain containing protein, putative
— OG7
LbrM.20.2060 ⚠
Guanine nucleotide exchange factor in Golgi t
— OG7
LbrM.34.5330 ⚠
HECT-domain (ubiquitin-transferase), putative
— OG7
LbrM.30.1210 ⚠
WW domain containing protein, putative
— OG7
LbrM.20.3550 ⚠
target of rapamycin kinase 3, putative
— OG7
LbrM.20.2440 ⚠
regulatory subunit of protein kinase a-like p
— OG7
LbrM.13.0150 ⚠
protein kinase A regulatory subunit
— OG7
LbrM.32.4210 ⚠
cAMP response protein 1, putative
— OG7
LbrM.17.1260 ⚠
5'-3' exoribonuclease B, putative
— OG7
LbrM.03.0980 ⚠
hypothetical protein
— OG7
LbrM.03.0280 ⚠
FYVE zinc finger/Apolipoprotein A1/A4/E domai
— OG7
LbrM.08.0010 ⚠
adaptor complex protein (AP) 3 delta subunit
— OG7
LbrM.13.1230 ⚠
SPRY domain/HECT-domain (ubiquitin-transferas
— OG7
LbrM.32.1620 ⚠
phosphatidylinositol 3-related kinase, putati
— OG7
LbrM.21.1760 ⚠
Microtubule-binding protein MIP-T3, putative
— OG7
LbrM.34.3440 ⚠
structural maintenance of chromosome (SMC) fa
— OG7
LbrM.16.1610 ⚠
hypothetical protein, conserved
— OG7
LbrM.18.0520 ⚠
tubulin-specific chaperone, putative
— OG7
LbrM.35.3160 ⚠
phosphatidylinositol 3- and 4-kinase, putativ
— OG7
LbrM.30.1030 ⚠
ubiquitin-protein ligase, putative
— OG7
LbrM.06.0840 ⚠
protein arginine n-methyltransferase 7
— OG7
LbrM.20.2170 ⚠
ruvB-like DNA helicase, putative
— OG7
LbrM.16.0040 ⚠
arginine N-methyltransferase, type I
— OG7
LbrM.34.1640 ⚠
ubiquitin hydrolase, putative, cysteine pepti
— OG7
LbrM.20.3690 ⚠
cysteine peptidase, Clan CA, family C19, puta
— OG7
LbrM.20.5280 ⚠
phosphatidylinositol 3-kinase, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.