LbrM.15.1240

cysteine peptidase, Clan CA, family C19, putative, ubiquitin hydrolase, putative
Leishmania braziliensis MHOM/BR/75/M2904 OG6: OG6_145141 OG7: OG7_0002166 239 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
Applies on "Apply filters".
Reset
⬇ CSV
Network view all shared interactors, plus up to 150 more
Show:
Selection: Shift+drag also box-selects. Drag any selected node to move the whole selection.
Interactions 239 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LbrM.19.1110 ⚠
ABC transport system ATP-binding protein, put
— OG7
LbrM.03.0170 ⚠
ABC transporter protein, putative
— Both
LbrM.33.0320 ⚠
ATP-binding cassette sub-family F member 1, p
— OG7
LbrM.23.0700 ⚠
ubiquitin-activating enzyme E1, putative
— OG7
LbrM.04.0070 ⚠
cAMP-specific phosphodiesterase, putative
— Both
LbrM.34.2970 ⚠
ubiquitin-activating enzyme E1, putative
— OG7
LbrM.05.0950 ⚠
3-mercaptopyruvate sulfurtransferase (fragmen
— OG7
LbrM.30.1320 ⚠
ubiquitin hydrolase, putative, cysteine pepti
— OG7
LbrM.17.0210 ⚠
WD domain, G-beta repeat, putative
— OG7
LbrM.35.7070 ⚠
replication factor C subunit 3, putative
— OG7
LbrM.34.0740 ⚠
proteasome activator protein pa26, putative
— OG7
LbrM.20.3590 ⚠
HECT-domain (ubiquitin-transferase), putative
— OG7
LbrM.20.4000 ⚠
13 kDa deflagellation-inducible protein, puta
— OG7
LbrM.24.1000 ⚠
replication factor C, subunit 1, putative
— OG7
LbrM.30.2590 ⚠
replication factor C, subunit 2, putative
— OG7
LbrM.17.0530 ⚠
ATPase family associated with various cellula
— OG7
LbrM.24.0630 ⚠
ubiquitin carboxyl-terminal hydrolase, putati
— OG7
LbrM.32.0850 ⚠
cyclin 9, putative
— OG7
LbrM.21.0460 ⚠
Peptidase C19, ubiquitin carboxyl-terminal hy
— OG7
LbrM.34.3170 ⚠
Peroxin 19
— OG7
LbrM.34.3160 ⚠
replication factor C, subunit 3, putative
— OG7
LbrM.32.1190 ⚠
HECT-domain (ubiquitin-transferase), putative
— OG7
LbrM.21.0910 ⚠
Temperature dependent protein affecting M2 ds
— OG7
LbrM.33.3240 ⚠
hypothetical protein, conserved
— OG7
LbrM.26.0750 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LbrM.35.4300 ⚠
regulator of chromosome condensation 1-like p
— OG7
LbrM.11.0100 ⚠
regulator of chromatin condensation, putative
— OG7
LbrM.31.3070 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LbrM.17.0220 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LbrM.35.2810 ⚠
cyclin-e binding protein 1-like protein
— OG7
LbrM.20.1520 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LbrM.26.0760 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LbrM.30.3120 ⚠
valyl-tRNA synthetase, putative
— OG7
LbrM.23.0660 ⚠
Galactose oxidase, central domain containing
— OG7
LbrM.34.4940 ⚠
PSP1 C-terminal conserved region, putative
— OG7
LbrM.34.0940 ⚠
cell cycle sequence binding phosphoprotein (R
— OG7
LbrM.35.4810 ⚠
PSP1 C-terminal conserved region, putative
— OG7
LbrM.29.1190 ⚠
PSP1 C-terminal conserved region, putative
— OG7
LbrM.28.1500 ⚠
hypothetical protein, conserved
— OG7
LbrM.10.0120 ⚠
PSP1 C-terminal conserved region, putative
— OG7
LbrM.20.2430 ⚠
Carboxypeptidase-like protein
— OG7
LbrM.11.0490 ⚠
anion-transporting ATPase-like protein
— OG7
LbrM.35.4270 ⚠
metallo-peptidase, Clan MC, Family M14, putat
— OG7
LbrM.08.0340 ⚠
Isochorismatase family, putative
— OG7
LbrM.33.0210 ⚠
metallo-peptidase, Clan MC, Family M14, putat
— OG7
LbrM.08.0360 ⚠
mitochondrial associated ribonuclease, putati
— OG7
LbrM.19.0180 ⚠
hypothetical protein, conserved
— OG7
LbrM.25.1360 ⚠
hypothetical protein, conserved
— OG7
LbrM.05.0470 ⚠
GTPase, putative
— OG7
LbrM.05.0970 ⚠
3-mercaptopyruvate sulfurtransferase
— OG7
Page 1 of 5
Next →
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.