LbrM.05.0470

GTPase, putative
Leishmania braziliensis MHOM/BR/75/M2904 OG6: OG6_101829 OG7: OG7_0001608 232 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 232 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LbrM.26.1180 ⚠
RNA pseudouridylate synthase, putative
— OG7
LbrM.27.0140 ⚠
WW domain/Zinc finger C-x8-C-x5-C-x3-H type (
— OG7
LbrM.18.0250 ⚠
60S ribosomal protein L7, putative
— OG7
LbrM.26.0160 ⚠
60S ribosomal protein L7, putative
— OG7
LbrM.26.0170 ⚠
60S ribosomal protein L7, putative
— OG7
LbrM.21.1280 ⚠
60S ribosomal protein L9, putative
— OG7
LbrM.30.3380 ⚠
60S ribosomal protein L9, putative
— OG7
LbrM.35.3130 ⚠
hypothetical protein, conserved
— OG7
LbrM.07.0560 ⚠
60S ribosomal protein L7a, putative
— OG7
LbrM.07.0570 ⚠
60S ribosomal protein L7a, putative
— OG7
LbrM.01.0030 ⚠
DNA-damage inducible protein DDI1-like protei
— OG7
LbrM.04.0740 ⚠
60S ribosomal protein L10, putative
— OG7
LbrM.04.0950 ⚠
60S ribosomal protein L10, putative
— OG7
LbrM.15.0210 ⚠
60S ribosomal protein L13a, putative
— OG7
LbrM.20.0830 ⚠
60S ribosomal protein L13a, putative
— OG7
LbrM.06.0580 ⚠
60S ribosomal protein L23a, putative
— OG7
LbrM.06.0590 ⚠
60S ribosomal protein L23a, putative
— OG7
LbrM.13.0130 ⚠
hypothetical protein, conserved
— OG7
LbrM.35.6120 ⚠
hypothetical protein, conserved
— OG7
LbrM.30.3680 ⚠
ribosomal protein L15, putative
— OG7
LbrM.34.1810 ⚠
ribosomal protein L15, putative
— OG7
LbrM.30.3070 ⚠
homoserine kinase
— OG7
LbrM.30.1090 ⚠
p22 protein precursor, putative
— OG7
LbrM.33.0210 ⚠
metallo-peptidase, Clan MC, Family M14, putat
— OG7
LbrM.34.2400 ⚠
ubiquitin-protein ligase, putative
— OG7
LbrM.35.4610 ⚠
ubiquitin protein ligase, putative
— OG7
LbrM.24.1960 ⚠
cyclin 10
— OG7
LbrM.30.3660 ⚠
CYC2-like protein, putative
— OG7
LbrM.26.0750 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LbrM.20.5910 ⚠
amidohydrolase, putative
— OG7
LbrM.35.0250 ⚠
elongation factor 2
— OG7
LbrM.26.0450 ⚠
nucleotide binding protein-like protein
— OG7
LbrM.12.0080 ⚠
ribonuclease mar1
— OG7
LbrM.34.2970 ⚠
ubiquitin-activating enzyme E1, putative
— OG7
LbrM.35.0270 ⚠
elongation factor 2
— OG7
LbrM.11.0100 ⚠
regulator of chromatin condensation, putative
— OG7
LbrM.17.1560 ⚠
zinc-finger protein ZPR1, putative
— OG7
LbrM.12.0300 ⚠
ornithine decarboxylase, putative
— OG7
LbrM.05.0720 ⚠
Vta1 like, putative
— OG7
LbrM.16.0560 ⚠
aspartate carbamoyltransferase, putative
— OG7
LbrM.10.1250 ⚠
Zinc finger, C3HC4 type (RING finger), putati
— OG7
LbrM.17.0610 ⚠
Acyl CoA binding protein, putative
— OG7
LbrM.14.1540 ⚠
myo-inositol-1-phosphate synthase, inositol-3
— OG7
LbrM.20.5920 ⚠
amidohydrolase, putative
— OG7
LbrM.23.0700 ⚠
ubiquitin-activating enzyme E1, putative
— OG7
LbrM.20.2300 ⚠
methyltransferase-like protein
— OG7
LbrM.17.1550 ⚠
zinc-finger protein ZPR1, putative
— OG7
LbrM.08.0350 ⚠
Isochorismatase family, putative
— OG7
LbrM.35.4300 ⚠
regulator of chromosome condensation 1-like p
— OG7
LbrM.19.1230 ⚠
peptidyl-prolyl cis-trans isomerase, macropha
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.