LbrM.12.0080

ribonuclease mar1
Leishmania braziliensis MHOM/BR/75/M2904 OG6: OG6_101675 OG7: OG7_0006505 105 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 105 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LbrM.30.1920 ⚠
C2H2 type zinc-finger (2 copies), putative
— OG7
LbrM.11.0620 ⚠
tubulin-tyrsoine ligase-like protein (fragmen
— OG7
LbrM.05.0770 ⚠
Mitochondrial glycoprotein, putative
— OG7
LbrM.22.1030 ⚠
Beta-lactamase superfamily domain containing
— OG7
LbrM.10.0690 ⚠
zinc binding dehydrogenase-like protein
— OG7
LbrM.35.0560 ⚠
dihydrouridine synthase domain protein-like p
— OG7
LbrM.31.3520 ⚠
metallo-peptidase, Clan ME, Family M16
— OG7
LbrM.20.4000 ⚠
13 kDa deflagellation-inducible protein, puta
— OG7
LbrM.35.0260 ⚠
elongation factor 2
— OG7
LbrM.16.0390 ⚠
tubulin tyrosine ligase, putative
— OG7
LbrM.33.1880 ⚠
cytosolic nonspecific dipeptidase, putative
— OG7
LbrM.13.1010 ⚠
Thiamin pyrophosphokinase, vitamin B1 binding
— OG7
LbrM.20.3590 ⚠
HECT-domain (ubiquitin-transferase), putative
— OG7
LbrM.35.4270 ⚠
metallo-peptidase, Clan MC, Family M14, putat
— OG7
LbrM.35.0250 ⚠
elongation factor 2
— OG7
LbrM.20.4970 ⚠
tubulin-tyrosine ligase, putative
— OG7
LbrM.27.0930 ⚠
WD domain, G-beta repeat, putative
— OG7
LbrM.26.0450 ⚠
nucleotide binding protein-like protein
— OG7
LbrM.34.2970 ⚠
ubiquitin-activating enzyme E1, putative
— OG7
LbrM.35.0270 ⚠
elongation factor 2
— OG7
LbrM.11.0100 ⚠
regulator of chromatin condensation, putative
— OG7
LbrM.16.0560 ⚠
aspartate carbamoyltransferase, putative
— OG7
LbrM.10.1250 ⚠
Zinc finger, C3HC4 type (RING finger), putati
— OG7
LbrM.27.2750 ⚠
ATP-dependent Clp protease subunit, heat shoc
— OG7
LbrM.16.0400 ⚠
XRN 5'-3' exonuclease N-terminus, putative
— OG7
LbrM.35.4300 ⚠
regulator of chromosome condensation 1-like p
— OG7
LbrM.20.2300 ⚠
methyltransferase-like protein
— OG7
LbrM.30.3070 ⚠
homoserine kinase
— OG7
LbrM.05.0220 ⚠
hydrogenase, putative
— OG7
LbrM.07.0100 ⚠
pitrilysin-like metalloprotease, metallo-pept
— OG7
LbrM.03.0510 ⚠
kinase-like protein
— OG7
LbrM.03.0650 ⚠
TatD related DNase, putative
— OG7
LbrM.05.0950 ⚠
3-mercaptopyruvate sulfurtransferase (fragmen
— OG7
LbrM.05.0970 ⚠
3-mercaptopyruvate sulfurtransferase
— OG7
LbrM.05.0470 ⚠
GTPase, putative
— OG7
LbrM.33.2680 ⚠
ras-like small GTPases, putative
— OG7
LbrM.34.5160 ⚠
hypothetical protein, conserved
— OG7
LbrM.26.1390 ⚠
GTP-binding protein-like protein, guanine nuc
— OG7
LbrM.05.0200 ⚠
50S ribosome-binding GTPase, putative
— OG7
LbrM.30.3480 ⚠
DNA ligase I, putative
— OG7
LbrM.35.4610 ⚠
ubiquitin protein ligase, putative
— OG7
LbrM.23.0700 ⚠
ubiquitin-activating enzyme E1, putative
— OG7
LbrM.28.2200 ⚠
hypothetical protein, conserved
— OG7
LbrM.27.2700 ⚠
tubulin-tyrosine ligase-like protein
— OG7
LbrM.26.0750 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LbrM.31.2100 ⚠
peptidase m20/m25/m40 family-like protein
— OG7
LbrM.26.2010 ⚠
hypothetical protein, unknown function
— OG7
LbrM.33.0210 ⚠
metallo-peptidase, Clan MC, Family M14, putat
— OG7
LbrM.31.2120 ⚠
peptidase m20/m25/m40 family-like protein
— OG7
LbrM.30.1090 ⚠
p22 protein precursor, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.