LbrM.20.4970

tubulin-tyrosine ligase, putative
Leishmania braziliensis MHOM/BR/75/M2904 OG6: OG6_137036 OG7: OG7_0001164 151 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 151 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LbrM.18.1690 ⚠
chaperone protein DnaJ, putative
— OG7
LbrM.28.2070 ⚠
DnaJ domain containing protein, putative
— OG7
LbrM.22.1540 ⚠
ccr4-not transcription complex subunit
— OG7
LbrM.20.1620 ⚠
ubiquitin-like protein
— OG7
LbrM.23.1670 ⚠
exosome component CSL4, putative
— OG7
LbrM.20.3130 ⚠
Programmed cell death protein 2, C-terminal p
— OG7
LbrM.28.2180 ⚠
hypothetical protein, conserved
— OG7
LbrM.23.1810 ⚠
neutral sphingomyelinase activation associate
— OG7
LbrM.20.5280 ⚠
phosphatidylinositol 3-kinase, putative
— OG7
LbrM.14.1440 ⚠
ubiquitin/ribosomal protein S27a, putative
— OG7
LbrM.26.0610 ⚠
hypothetical protein, conserved
— OG7
LbrM.19.0390 ⚠
DnaJ domain containing protein, putative
— OG7
LbrM.35.3280 ⚠
cullin-like protein
— OG7
LbrM.33.3060 ⚠
Concanavalin A-like lectin/glucanases superfa
— OG7
LbrM.32.2890 ⚠
SpoU rRNA Methylase family, putative
— OG7
LbrM.09.0250 ⚠
DNA replication licensing factor MCM4, putati
— OG7
LbrM.05.0320 ⚠
DNA replication licensing factor MCM8, putati
— OG7
LbrM.17.0950 ⚠
formin, putative
— OG7
LbrM.20.3990 ⚠
Phosphatidylinositol 3-kinase tor2
— OG7
LbrM.28.0920 ⚠
DNA replication licensing factor MCM2, putati
— OG7
LbrM.26.2000 ⚠
hypothetical protein, conserved
— OG7
LbrM.18.0920 ⚠
Periodic tryptophan protein 2 homolog, putati
— OG7
LbrM.05.1110 ⚠
DNA-directed RNA polymerase I largest subunit
— OG7
LbrM.31.2130 ⚠
ubiquitin-fusion protein
— OG7
LbrM.35.2620 ⚠
Cullin protein neddylation domain containing
— OG7
LbrM.25.1240 ⚠
Cullin family/Cullin protein neddylation doma
— OG7
LbrM.33.2980 ⚠
DNA replication licensing factor MCM3, putati
— OG7
LbrM.24.1120 ⚠
formin-like protein
— OG7
LbrM.31.2950 ⚠
RNA polymerase ii largest subunit
— OG7
LbrM.20.3550 ⚠
target of rapamycin kinase 3, putative
— OG7
LbrM.35.3010 ⚠
Flagellar Member 1
— OG7
LbrM.35.2230 ⚠
hypothetical protein, conserved
— OG7
LbrM.34.4870 ⚠
DNA replication licensing factor MCM9, putati
— OG7
LbrM.24.0920 ⚠
DNA replication licensing factor MCM5, putati
— OG7
LbrM.19.1210 ⚠
hypothetical protein, conserved
— OG7
LbrM.35.0560 ⚠
dihydrouridine synthase domain protein-like p
— OG7
LbrM.35.7120 ⚠
beta adaptin, putative
— OG7
LbrM.33.2870 ⚠
hypothetical protein, conserved
— OG7
LbrM.04.0540 ⚠
hypothetical protein, conserved
— OG7
LbrM.25.0490 ⚠
hypothetical protein, conserved
— OG7
LbrM.04.1190 ⚠
Double RNA binding domain protein 3
— OG7
LbrM.35.0720 ⚠
ubiquitin/ribosomal protein S27a, putative
— OG7
LbrM.35.1910 ⚠
hypothetical protein, conserved
— OG7
LbrM.32.0940 ⚠
polypyrimidine tract-binding protein, putativ
— OG7
LbrM.35.0730 ⚠
DNAJ protein-like protein
— OG7
LbrM.19.0060 ⚠
hypothetical protein, conserved
— OG7
LbrM.35.1390 ⚠
fructose-1,6-bisphosphate aldolase
— OG7
LbrM.01.0170 ⚠
hypothetical protein, conserved
— OG7
LbrM.11.0150 ⚠
pumillio protein 10, putative
— OG7
LbrM.14.0550 ⚠
WD domain, G-beta repeat, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.