LbrM.20.5280

phosphatidylinositol 3-kinase, putative
Leishmania braziliensis MHOM/BR/75/M2904 OG6: OG6_139742 OG7: OG7_0001934 333 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 333 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LbrM.35.5490 ⚠
glycosyl hydrolase, putative
— OG7
LbrM.31.2990 ⚠
acetoin dehydrogenase e3 component-like prote
— OG7
LbrM.31.0230 ⚠
dihydrolipoamide dehydrogenase
— OG7
LbrM.31.2980 ⚠
2-oxoglutarate dehydrogenase, e3 component, l
— OG7
LbrM.33.1750 ⚠
hypothetical protein, conserved
— OG7
LbrM.32.3090 ⚠
CS domain/TPR repeat/Tetratricopeptide repeat
— OG7
LbrM.08.0480 ⚠
hypothetical protein, conserved
— OG7
LbrM.26.1140 ⚠
axonemal dynein light chain, putative
— OG7
LbrM.33.1390 ⚠
Axonemal inner arm dynein light chain, putati
— OG7
LbrM.13.0500 ⚠
Metallopeptidase family M24, putative
— OG7
LbrM.21.1250 ⚠
dynein arm light chain, putative
— OG7
LbrM.19.0470 ⚠
metallo-peptidase, Clan MG, Family M24
— OG7
LbrM.20.5370 ⚠
dynein arm light chain, putative
— OG7
LbrM.32.3410 ⚠
ribosomal protein L3, putative (fragment)
— OG7
LbrM.32.3420 ⚠
ribosomal protein L3, putative
— OG7
LbrM.35.1480 ⚠
adenylate kinase, putative
— OG7
LbrM.16.0030 ⚠
AAA domain containing protein, putative
— OG7
LbrM.04.0960 ⚠
adenylate kinase, putative
— OG7
LbrM.21.1450 ⚠
adenylate kinase, putative
— OG7
LbrM.04.0830 ⚠
hypothetical protein, conserved
— OG7
LbrM.18.0920 ⚠
Periodic tryptophan protein 2 homolog, putati
— OG7
LbrM.32.1520 ⚠
RNA capping enzyme, cytoplasmic
— OG7
LbrM.04.0680 ⚠
hypothetical protein, conserved (fragment)
— OG7
LbrM.11.0060 ⚠
hypothetical protein, conserved
— OG7
LbrM.16.0650 ⚠
hypothetical protein, conserved
— OG7
LbrM.28.1620 ⚠
Cell division control protein 48, putative
— OG7
LbrM.17.1340 ⚠
hypothetical protein, conserved
— OG7
LbrM.31.0340 ⚠
hypothetical protein, conserved
— OG7
LbrM.24.2180 ⚠
hypothetical protein, conserved
— OG7
LbrM.21.1280 ⚠
60S ribosomal protein L9, putative
— OG7
LbrM.30.3380 ⚠
60S ribosomal protein L9, putative
— OG7
LbrM.23.1500 ⚠
DNA polymerase theta (helicase domain only),
— OG7
LbrM.02.0170 ⚠
RNA helicase, putative (fragment)
— OG7
LbrM.17.0940 ⚠
ATP-dependent RNA helicase, putative
— OG7
LbrM.13.0320 ⚠
ATP-dependent RNA helicase, putative
— OG7
LbrM.32.1560 ⚠
ATP-dependent DNA DEAD/DEAH box helicase, put
— OG7
LbrM.07.0770 ⚠
topoisomerase-related function protein-like p
— OG7
LbrM.26.0510 ⚠
DNA polymerase sigma-like protein
— OG7
LbrM.04.0550 ⚠
Nucleotidyltransferase domain containing prot
— OG7
LbrM.20.0330 ⚠
DNA-directed RNA polymerase III subunit C1, p
— OG7
LbrM.35.1910 ⚠
hypothetical protein, conserved
— OG7
LbrM.16.1400 ⚠
DNA-directed rna polymerase I largest subunit
— OG7
LbrM.23.0130 ⚠
Concanavalin A-like lectin/glucanases superfa
— OG7
LbrM.31.2950 ⚠
RNA polymerase ii largest subunit
— OG7
LbrM.33.3060 ⚠
Concanavalin A-like lectin/glucanases superfa
— OG7
LbrM.20.4970 ⚠
tubulin-tyrosine ligase, putative
— OG7
LbrM.31.1560 ⚠
hypothetical protein, conserved
— OG7
LbrM.27.2700 ⚠
tubulin-tyrosine ligase-like protein
— OG7
LbrM.34.1810 ⚠
ribosomal protein L15, putative
— OG7
LbrM.29.2710 ⚠
hypothetical protein, conserved
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.