LbrM.13.0320

ATP-dependent RNA helicase, putative
Leishmania braziliensis MHOM/BR/75/M2904 OG6: OG6_100305 OG7: OG7_0001850 142 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 142 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LbrM.25.1240 ⚠
Cullin family/Cullin protein neddylation doma
— Both
LbrM.34.3940 ⚠
PRP8 protein homologue, putative, U5 snRNA-as
— Both
LbrM.28.2310 ⚠
Cullin family/Cullin protein neddylation doma
— OG7
LbrM.35.2620 ⚠
Cullin protein neddylation domain containing
— OG7
LbrM.35.3280 ⚠
cullin-like protein
— OG7
LbrM.24.2370 ⚠
cullin-like protein-like protein
— OG7
LbrM.16.1260 ⚠
Cullin family/Cullin protein neddylation doma
— OG7
LbrM.31.3340 ⚠
acetyl-CoA carboxylase
— Both
LbrM.19.1260 ⚠
FYVE zinc finger, putative
— OG7
LbrM.14.0550 ⚠
WD domain, G-beta repeat, putative
— Both
LbrM.31.1080 ⚠
protein phosphatase 2C, putative
— OG6
LbrM.16.1400 ⚠
DNA-directed rna polymerase I largest subunit
— Both
LbrM.20.1390 ⚠
Nucleoporin NUP225
— Both
LbrM.34.3440 ⚠
structural maintenance of chromosome (SMC) fa
— Both
LbrM.13.0890 ⚠
proteasome regulatory ATPase subunit 2, putat
— OG6
LbrM.08.0010 ⚠
adaptor complex protein (AP) 3 delta subunit
— Both
LbrM.15.1130 ⚠
cyclic nucleotide-binding domain containing p
— Both
LbrM.02.0400 ⚠
proteasome regulatory non-ATPase subunit 6, p
— Both
LbrM.27.1600 ⚠
proteasome regulatory non-ATP-ase subunit 3,
— Both
LbrM.08.0540 ⚠
ribose-phosphate pyrophosphokinase, putative
— Both
LbrM.32.2420 ⚠
U5 small nuclear ribonucleoprotein component,
— Both
LbrM.32.4170 ⚠
SPRY domain/HECT-domain (ubiquitin-transferas
— Both
LbrM.35.4600 ⚠
19S proteasome regulatory subunit, Regulatory
— OG6
LbrM.33.0280 ⚠
hypothetical protein, conserved
— Both
LbrM.32.2340 ⚠
RNA recognition motif. (a.k.a. RRM, RBD, or R
— Both
LbrM.35.5650 ⚠
phosphoribosylpyrophosphate synthetase, putat
— OG7
LbrM.08.0900 ⚠
phosphoribosylpyrophosphate synthetase
— OG7
LbrM.33.2210 ⚠
phosphoribosyl transferase, putative, phospho
— OG7
LbrM.10.0900 ⚠
hypothetical protein, conserved
— OG7
LbrM.20.4080 ⚠
cyclic nucleotide-binding domain containing p
— OG7
LbrM.34.3430 ⚠
zinc finger protein, putative
— OG7
LbrM.32.1520 ⚠
RNA capping enzyme, cytoplasmic
— OG7
LbrM.05.0410 ⚠
structural maintenance of chromosome (SMC), p
— OG7
LbrM.35.6620 ⚠
Phosphatidylinositol 3-kinase tor1
— OG7
LbrM.20.4090 ⚠
DNA-directed RNA polymerase III, putative
— OG7
LbrM.29.0150 ⚠
DNA-directed RNA polymerase II subunit 3, put
— OG7
LbrM.06.0510 ⚠
SpoU rRNA Methylase family, putative
— OG7
LbrM.34.5330 ⚠
HECT-domain (ubiquitin-transferase), putative
— OG7
LbrM.02.0130 ⚠
phosphatidylinositol kinase related protein,
— OG7
LbrM.27.1390 ⚠
ubiquitin carboxyl-terminal hydrolase, putati
— OG7
LbrM.32.1620 ⚠
phosphatidylinositol 3-related kinase, putati
— OG7
LbrM.16.1170 ⚠
WW domain containing protein, putative
— OG7
LbrM.35.1480 ⚠
adenylate kinase, putative
— OG7
LbrM.26.1280 ⚠
hypothetical protein, unknown function
— OG7
LbrM.34.4240 ⚠
hypothetical protein, conserved
— OG7
LbrM.35.1910 ⚠
hypothetical protein, conserved
— OG7
LbrM.30.1030 ⚠
ubiquitin-protein ligase, putative
— OG7
LbrM.34.2360 ⚠
cysteine peptidase, Clan CA, family C19, puta
— OG7
LbrM.19.1110 ⚠
ABC transport system ATP-binding protein, put
— OG7
LbrM.35.0270 ⚠
elongation factor 2
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.