LbrM.33.0280

hypothetical protein, conserved
Leishmania braziliensis MHOM/BR/75/M2904 OG6: OG6_103995 OG7: OG7_0008721 108 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 108 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LbrM.32.2340
RNA recognition motif. (a.k.a. RRM, RBD, or R
— Both
LbrM.22.0510
proteasome regulatory ATPase subunit 1, putat
— OG6
LbrM.34.5330 ⚠
HECT-domain (ubiquitin-transferase), putative
— OG7
LbrM.29.1050
kinesin, putative
— OG6
LbrM.32.0380
intraflagellar transport protein 140, putativ
— Both
LbrM.02.0400
proteasome regulatory non-ATPase subunit 6, p
— Both
LbrM.32.4190
hypothetical protein, conserved
— Both
LbrM.14.0900
immunodominant antigen, putative, tc40 antige
— Both
LbrM.26.1870
microtubule-associated protein, putative
— Both
LbrM.27.1600
proteasome regulatory non-ATP-ase subunit 3,
— Both
LbrM.22.1400
ATP-dependent DEAD/H RNA helicase, putative
— OG6
LbrM.32.4170
SPRY domain/HECT-domain (ubiquitin-transferas
— Both
LbrM.12.0020 ⚠
translation initiation factor EIF-2b alpha su
— Both
LbrM.35.4600
19S proteasome regulatory subunit, Regulatory
— OG6
LbrM.07.1200
proteasome regulatory non-ATP-ase subunit, pu
— Both
LbrM.19.1440
proteasome regulatory non-ATP-ase subunit 9,
— Both
LbrM.12.0230
proteasome regulatory ATPase subunittcc1l8.3,
— OG6
LbrM.17.0940 ⚠
ATP-dependent RNA helicase, putative
— Both
LbrM.32.0460
19S proteasome non-atpase subunit 8
— Both
LbrM.17.0810
OSM3-like kinesin, putative
— OG6
LbrM.29.0130
proteasome regulatory non-ATPase subunit, put
— Both
LbrM.15.1130 ⚠
cyclic nucleotide-binding domain containing p
— Both
LbrM.21.0840
proteasome regulatory non-ATP-ase subunit 5,
— Both
LbrM.13.0320 ⚠
ATP-dependent RNA helicase, putative
— Both
LbrM.09.1270
AAA family ATPase, putative
— Both
LbrM.16.1610 ⚠
hypothetical protein, conserved
— OG7
LbrM.27.1310 ⚠
translation initiation factor eIF2B delta sub
— OG7
LbrM.20.1950 ⚠
Sec7 domain containing protein, putative
— OG7
LbrM.33.1390 ⚠
Axonemal inner arm dynein light chain, putati
— OG7
LbrM.20.2440 ⚠
regulatory subunit of protein kinase a-like p
— OG7
LbrM.13.0150 ⚠
protein kinase A regulatory subunit
— OG7
LbrM.32.4210 ⚠
cAMP response protein 1, putative
— OG7
LbrM.08.0010 ⚠
adaptor complex protein (AP) 3 delta subunit
— OG7
LbrM.34.3440 ⚠
structural maintenance of chromosome (SMC) fa
— OG7
LbrM.13.1230 ⚠
SPRY domain/HECT-domain (ubiquitin-transferas
— OG7
LbrM.17.1260 ⚠
5'-3' exoribonuclease B, putative
— OG7
LbrM.03.0980 ⚠
hypothetical protein
— OG7
LbrM.03.0280 ⚠
FYVE zinc finger/Apolipoprotein A1/A4/E domai
— OG7
LbrM.32.1620 ⚠
phosphatidylinositol 3-related kinase, putati
— OG7
LbrM.20.3550 ⚠
target of rapamycin kinase 3, putative
— OG7
LbrM.20.5280 ⚠
phosphatidylinositol 3-kinase, putative
— OG7
LbrM.35.3160 ⚠
phosphatidylinositol 3- and 4-kinase, putativ
— OG7
LbrM.20.4080 ⚠
cyclic nucleotide-binding domain containing p
— OG7
LbrM.24.2040
hypothetical protein, conserved
— Both
LbrM.30.1210 ⚠
WW domain containing protein, putative
— OG7
LbrM.16.1170 ⚠
WW domain containing protein, putative
— OG7
LbrM.30.1030 ⚠
ubiquitin-protein ligase, putative
— OG7
LbrM.21.1760 ⚠
Microtubule-binding protein MIP-T3, putative
— OG7
LbrM.18.0520 ⚠
tubulin-specific chaperone, putative
— OG7
LbrM.23.1500 ⚠
DNA polymerase theta (helicase domain only),
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.