LbrM.22.0510

proteasome regulatory ATPase subunit 1, putative
Leishmania braziliensis MHOM/BR/75/M2904 OG6: OG6_101899 OG7: OG7_0000949 78 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 78 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LbrM.02.0400
proteasome regulatory non-ATPase subunit 6, p
— OG6
LbrM.32.3060
proteasome regulatory non-ATP-ase subunit, pu
— OG6
LbrM.03.0450
serine peptidase, Clan SJ, family S16, putati
— OG6
LbrM.32.1350
proteasome regulatory non-ATP-ase subunit, pu
— OG6
LbrM.13.0890
proteasome regulatory ATPase subunit 2, putat
— OG6
LbrM.20.0580
proteasome regulatory non-ATPase subunit 11,
— OG6
LbrM.35.4600
19S proteasome regulatory subunit, Regulatory
— OG6
LbrM.07.1200
proteasome regulatory non-ATP-ase subunit, pu
— OG6
LbrM.12.0230
proteasome regulatory ATPase subunittcc1l8.3,
— OG6
LbrM.21.0840
proteasome regulatory non-ATP-ase subunit 5,
— OG6
LbrM.22.0560
proteasome regulatory ATPase subunit 5, putat
— OG6
LbrM.19.1440
proteasome regulatory non-ATP-ase subunit 9,
— OG6
LbrM.33.0280
hypothetical protein, conserved
— OG6
LbrM.27.1600
proteasome regulatory non-ATP-ase subunit 3,
— OG6
LbrM.29.0130
proteasome regulatory non-ATPase subunit, put
— OG6
LbrM.32.0460
19S proteasome non-atpase subunit 8
— OG6
LbrM.28.1900
proteasome regulatory non-ATP-ase subunit 2,
— OG6
LbrM.14.1200
hypothetical protein, conserved
— OG6
LbrM.02.0130
phosphatidylinositol kinase related protein,
— OG6
LbrM.20.4470 ⚠
Midasin, putative
— OG6
LbrM.20.4460 ⚠
Midasin, putative
— OG6
LbrM.04.0890
axonemal dynein light chain, putative
— OG6
LbrM.19.1000 ⚠
Flagellum attachment zone protein 7
— OG6
LbrM.19.1160 ⚠
kinesin, putative (fragment)
— OG6
LbrM.19.1150 ⚠
Flagellum attachment zone protein 7 (fragment
— OG6
LbrM.14.0900
immunodominant antigen, putative, tc40 antige
— OG6
LbrM.12.0020
translation initiation factor EIF-2b alpha su
— OG6
LbrM.26.1870
microtubule-associated protein, putative
— OG6
LbrM.35.6640
ubiquitin-protein ligase, putative
— OG6
LbrM.25.1400
General negative regulator of transcription s
— OG6
LbrM.26.1140
axonemal dynein light chain, putative
— OG6
LbrM.29.1260
hypothetical protein, conserved
— OG6
LbrM.32.0380
intraflagellar transport protein 140, putativ
— OG6
LbrM.35.6620 ⚠
Phosphatidylinositol 3-kinase tor1
— OG6
LbrM.29.1050
kinesin, putative
— OG6
LbrM.23.1010
hypothetical protein, conserved
— OG6
LbrM.30.0060
MATH domain containing protein, putative
— OG6
LbrM.30.0570
hypothetical protein, conserved
— OG6
LbrM.22.1400
ATP-dependent DEAD/H RNA helicase, putative
— OG6
LbrM.20.3990 ⚠
Phosphatidylinositol 3-kinase tor2
— OG6
LbrM.33.1750
hypothetical protein, conserved
— OG6
LbrM.09.1270
AAA family ATPase, putative
— OG6
LbrM.32.1630
Microtubule-binding protein MIP-T3, putative
— OG6
LbrM.32.0760
OSM3-like kinesin, putative
— OG6
LbrM.32.1060
hypothetical protein, conserved
— OG6
LbrM.24.2040
hypothetical protein, conserved
— OG6
LbrM.27.2350
hypothetical protein, conserved
— OG6
LbrM.17.0810
OSM3-like kinesin, putative
— OG6
LbrM.15.1140
protein kinase, putative
— OG6
LbrM.21.1570
RecF/RecN/SMC N terminal domain/SMC proteins
— OG6
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.