LbrM.22.1400

ATP-dependent DEAD/H RNA helicase, putative
Leishmania braziliensis MHOM/BR/75/M2904 OG6: OG6_126543 OG7: OG7_0000698 93 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 93 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LbrM.30.0570
hypothetical protein, conserved
— OG6
LbrM.35.6040
Rab3 GTPase-activating protein regulatory sub
— OG6
LbrM.32.0380
intraflagellar transport protein 140, putativ
— OG6
LbrM.35.1090
hypothetical protein, conserved
— OG6
LbrM.27.2350
hypothetical protein, conserved
— OG6
LbrM.34.3190 ⚠
60S ribosomal subunit protein L31, putative
— OG6
LbrM.30.2390
hypothetical protein, conserved
— OG6
LbrM.24.2040
hypothetical protein, conserved
— OG6
LbrM.13.1360
hypothetical protein, conserved
— OG6
LbrM.32.0760
OSM3-like kinesin, putative
— OG6
LbrM.35.6450
hypothetical protein, conserved
— OG6
LbrM.25.2040
Putative intraflagellar transport protein A1
— OG6
LbrM.33.2830
Unc104-like kinesin, putative
— OG6
LbrM.33.1750
hypothetical protein, conserved
— OG6
LbrM.30.0060
MATH domain containing protein, putative
— OG6
LbrM.32.1630
Microtubule-binding protein MIP-T3, putative
— OG6
LbrM.30.3470
protein mkt1, putative
— OG6
LbrM.23.1010
hypothetical protein, conserved
— OG6
LbrM.28.0240
hypothetical protein, unknown function
— OG6
LbrM.35.6620 ⚠
Phosphatidylinositol 3-kinase tor1
— OG6
LbrM.35.5920
Cyclin 12, L-type
— OG6
LbrM.35.2690
hypothetical protein, conserved
— OG6
LbrM.28.2940
hypothetical protein, conserved
— OG6
LbrM.25.1400
General negative regulator of transcription s
— OG6
LbrM.29.1310
COPII coat assembly protein sec16, putative
— OG6
LbrM.06.0170
hypothetical protein, conserved
— OG6
LbrM.09.1270
AAA family ATPase, putative
— OG6
LbrM.18.1480
Protein of unknown function (DUF3648), putati
— OG6
LbrM.22.0510
proteasome regulatory ATPase subunit 1, putat
— OG6
LbrM.04.0380
hypothetical protein, conserved
— OG6
LbrM.01.0480
Ring finger domain/Zn-finger in ubiquitin-hyd
— OG6
LbrM.12.0020
translation initiation factor EIF-2b alpha su
— OG6
LbrM.15.0960
protein phosphatase 2A regulatory subunit, pu
— OG6
LbrM.16.0720
ubiquitin hydrolase, putative, cysteine pepti
— OG6
LbrM.34.1630
casein kinase II, putative
— OG6
LbrM.26.1870
microtubule-associated protein, putative
— OG6
LbrM.34.3270
Putative death-receptor fusion protein (DUF24
— OG6
LbrM.29.2640
serine/threonine-protein kinase Nek, putative
— OG6
LbrM.30.2690
Stabilization of polarity axis, putative
— OG6
LbrM.26.1140
axonemal dynein light chain, putative
— OG6
LbrM.34.3200 ⚠
60S ribosomal subunit protein L31, putative
— OG6
LbrM.29.1260
hypothetical protein, conserved
— OG6
LbrM.14.1200
hypothetical protein, conserved
— OG6
LbrM.29.1050
kinesin, putative
— OG6
LbrM.33.0280
hypothetical protein, conserved
— OG6
LbrM.20.3990 ⚠
Phosphatidylinositol 3-kinase tor2
— OG6
LbrM.33.3200
hypothetical protein, conserved
— OG6
LbrM.30.0660
AMP-binding enzyme, putative
— OG6
LbrM.07.0290
ubiquitin-protein ligase-like, putative
— OG6
LbrM.06.0240 ⚠
5'-3' exoribonuclease A, putative
— OG6
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.