LbrM.35.2690

hypothetical protein, conserved
Leishmania braziliensis MHOM/BR/75/M2904 OG6: OG6_147018 OG7: OG7_0042983 108 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 108 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LbrM.32.1720 ⚠
PSP1 C-terminal conserved region, putative
— OG7
LbrM.08.0730
Beta-lactamase superfamily domain containing
— Both
LbrM.33.2150
hypothetical protein, conserved
— Both
LbrM.29.1790 ⚠
MORN repeat, putative
— Both
LbrM.28.2080
p21-C-terminal region-binding protein, putati
— Both
LbrM.22.1400
ATP-dependent DEAD/H RNA helicase, putative
— OG6
LbrM.16.0720 ⚠
ubiquitin hydrolase, putative, cysteine pepti
— Both
LbrM.18.1100
5-oxoprolinase, putative
— Both
LbrM.24.0500
Leucine Rich repeats (2 copies)/Leucine rich
— Both
LbrM.15.0960
protein phosphatase 2A regulatory subunit, pu
— Both
LbrM.01.0480 ⚠
Ring finger domain/Zn-finger in ubiquitin-hyd
— Both
LbrM.27.0370
hypothetical protein, conserved
— Both
LbrM.04.0380
hypothetical protein, conserved
— Both
LbrM.18.1480
Protein of unknown function (DUF3648), putati
— Both
LbrM.34.3270
Putative death-receptor fusion protein (DUF24
— Both
LbrM.29.2640
serine/threonine-protein kinase Nek, putative
— OG6
LbrM.06.0170
hypothetical protein, conserved
— Both
LbrM.30.3470 ⚠
protein mkt1, putative
— Both
LbrM.21.0460 ⚠
Peptidase C19, ubiquitin carboxyl-terminal hy
— OG7
LbrM.24.0630 ⚠
ubiquitin carboxyl-terminal hydrolase, putati
— OG7
LbrM.30.1320 ⚠
ubiquitin hydrolase, putative, cysteine pepti
— OG7
LbrM.17.0210 ⚠
WD domain, G-beta repeat, putative
— OG7
LbrM.10.0191 ⚠
hypothetical protein, conserved
— OG7
LbrM.34.5330 ⚠
HECT-domain (ubiquitin-transferase), putative
— OG7
LbrM.07.0290 ⚠
ubiquitin-protein ligase-like, putative
— OG7
LbrM.30.1210 ⚠
WW domain containing protein, putative
— OG7
LbrM.30.1030 ⚠
ubiquitin-protein ligase, putative
— OG7
LbrM.09.1220 ⚠
hypothetical protein, conserved
— OG7
LbrM.21.0910 ⚠
Temperature dependent protein affecting M2 ds
— OG7
LbrM.34.2290 ⚠
poly(A)-specific ribonuclease PARN, putative
— OG7
LbrM.30.0540 ⚠
aspartyl-tRNA synthetase, putative
— OG7
LbrM.21.1130 ⚠
aspartyl-tRNA synthetase, putative
— OG7
LbrM.20.2860 ⚠
Zn-finger in ubiquitin-hydrolases and other p
— OG7
LbrM.34.4240 ⚠
hypothetical protein, conserved
— OG7
LbrM.26.1280 ⚠
hypothetical protein, unknown function
— OG7
LbrM.14.1340 ⚠
ras-like small GTPases, putative
— OG7
LbrM.18.0660 ⚠
Zn-finger in Ran binding protein and others/F
— OG7
LbrM.26.1440 ⚠
FYVE zinc finger, putative
— OG7
LbrM.19.1260 ⚠
FYVE zinc finger, putative
— OG7
LbrM.20.4500 ⚠
developmentally regulated phosphoprotein-like
— OG7
LbrM.20.3510 ⚠
Histidine kinase-, DNA gyrase B-, and HSP90-l
— OG7
LbrM.25.1360 ⚠
hypothetical protein, conserved
— OG7
LbrM.34.0940 ⚠
cell cycle sequence binding phosphoprotein (R
— OG7
LbrM.35.4810 ⚠
PSP1 C-terminal conserved region, putative
— OG7
LbrM.29.1190 ⚠
PSP1 C-terminal conserved region, putative
— OG7
LbrM.28.1500 ⚠
hypothetical protein, conserved
— OG7
LbrM.10.0120 ⚠
PSP1 C-terminal conserved region, putative
— OG7
LbrM.19.0180 ⚠
hypothetical protein, conserved
— OG7
LbrM.32.1490 ⚠
PPPDE putative peptidase domain containing pr
— OG7
LbrM.20.3690 ⚠
cysteine peptidase, Clan CA, family C19, puta
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.