LbrM.32.1490

PPPDE putative peptidase domain containing protein, putative
Leishmania braziliensis MHOM/BR/75/M2904 OG6: OG6_146568 OG7: OG7_0003062 60 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 60 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LbrM.20.4500 ⚠
developmentally regulated phosphoprotein-like
— OG7
LbrM.33.2150 ⚠
hypothetical protein, conserved
— OG7
LbrM.28.2080 ⚠
p21-C-terminal region-binding protein, putati
— OG7
LbrM.35.3080 ⚠
hypothetical protein, conserved
— OG7
LbrM.14.1340 ⚠
ras-like small GTPases, putative
— OG7
LbrM.30.0540 ⚠
aspartyl-tRNA synthetase, putative
— OG7
LbrM.27.0370 ⚠
hypothetical protein, conserved
— OG7
LbrM.10.0191 ⚠
hypothetical protein, conserved
— OG7
LbrM.26.1280 ⚠
hypothetical protein, unknown function
— OG7
LbrM.31.1700 ⚠
hypothetical protein, unknown function
— OG7
LbrM.34.4240 ⚠
hypothetical protein, conserved
— OG7
LbrM.21.0240 ⚠
CHAT domain containing protein, putative
— OG7
LbrM.24.0500 ⚠
Leucine Rich repeats (2 copies)/Leucine rich
— OG7
LbrM.10.0820 ⚠
hypothetical protein, conserved
— OG7
LbrM.20.3510 ⚠
Histidine kinase-, DNA gyrase B-, and HSP90-l
— OG7
LbrM.27.1490 ⚠
hypothetical protein, unknown function
— OG7
LbrM.24.0010 ⚠
pyruvate dehydrogenase (lipoamide) kinase, pu
— OG7
LbrM.21.0530 ⚠
vacuolar sorting-associated-like protein
— OG7
LbrM.07.0990 ⚠
Domain of unknown function (DUF3437), putativ
— OG7
LbrM.19.1320 ⚠
phenylalanyl-tRNA synthetase, putative
— OG7
LbrM.04.0620 ⚠
DENN (AEX-3) domain containing protein, putat
— OG7
LbrM.16.1190 ⚠
hypothetical protein, conserved
— OG7
LbrM.12.0270 ⚠
cysteinyl-tRNA synthetase, putative
— OG7
LbrM.15.0450 ⚠
hypothetical protein, conserved
— OG7
LbrM.33.2890 ⚠
Mitochondrial-processing peptidase subunit al
— OG7
LbrM.34.2290 ⚠
poly(A)-specific ribonuclease PARN, putative
— OG7
LbrM.21.0400 ⚠
mitochondrial processing peptidase alpha subu
— OG7
LbrM.13.0680 ⚠
metallo-peptidase, Clan ME, Family M16, mitoc
— OG7
LbrM.23.0650 ⚠
poly(A)-specific ribonuclease PARN, putative
— OG7
LbrM.35.6680 ⚠
poly(A)-specific ribonuclease PARN, putative
— OG7
LbrM.16.1170 ⚠
WW domain containing protein, putative
— OG7
LbrM.07.0960 ⚠
protein kinase, putative, serine/threonine ki
— OG7
LbrM.29.1990 ⚠
5'-AMP-activated protein kinase catalytic sub
— OG7
LbrM.28.2190 ⚠
protein lipid droplet kinase (LDK)
— OG7
LbrM.18.0720 ⚠
serine/threonine kinase-like protein, putativ
— OG7
LbrM.22.0750 ⚠
protein kinase, putative, serine/threonine pr
— OG7
LbrM.35.1020 ⚠
SNF1-related protein kinases, putative
— OG7
LbrM.33.1980 ⚠
protein kinase, putative
— OG7
LbrM.14.0470 ⚠
cystathionine beta-lyase-like protein
— OG7
LbrM.34.3140 ⚠
cystathione gamma lyase, putative
— OG7
LbrM.29.2690 ⚠
Lipase (class 3), putative
— OG7
LbrM.17.0380 ⚠
Ring finger domain containing protein, putati
— OG7
LbrM.34.5330 ⚠
HECT-domain (ubiquitin-transferase), putative
— OG7
LbrM.07.0290 ⚠
ubiquitin-protein ligase-like, putative
— OG7
LbrM.30.1210 ⚠
WW domain containing protein, putative
— OG7
LbrM.21.0210 ⚠
serine/threonine-protein kinase-like protein
— OG7
LbrM.30.1030 ⚠
ubiquitin-protein ligase, putative
— OG7
LbrM.21.1960 ⚠
hypothetical protein, conserved
— OG7
LbrM.18.1100 ⚠
5-oxoprolinase, putative
— OG7
LbrM.34.3430 ⚠
zinc finger protein, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.