LbrM.14.1340

ras-like small GTPases, putative
Leishmania braziliensis MHOM/BR/75/M2904 OG6: OG6_147208 OG7: OG7_0001169 241 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 241 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LbrM.30.1030 ⚠
ubiquitin-protein ligase, putative
— OG7
LbrM.16.1170 ⚠
WW domain containing protein, putative
— OG7
LbrM.30.1210 ⚠
WW domain containing protein, putative
— OG7
LbrM.07.0290 ⚠
ubiquitin-protein ligase-like, putative
— OG7
LbrM.34.5330 ⚠
HECT-domain (ubiquitin-transferase), putative
— OG7
LbrM.11.0690 ⚠
hypothetical protein, conserved
— OG7
LbrM.20.5280 ⚠
phosphatidylinositol 3-kinase, putative
— OG7
LbrM.29.0610 ⚠
hypothetical protein, conserved
— OG7
LbrM.20.1740 ⚠
Glycosyl hydrolase family 65 central catalyti
— OG7
LbrM.33.1310 ⚠
hypothetical protein, conserved
— OG7
LbrM.30.2390 ⚠
hypothetical protein, conserved
— OG7
LbrM.33.3020 ⚠
translation initiation factor IF-2, putative
— OG7
LbrM.30.0540 ⚠
aspartyl-tRNA synthetase, putative
— OG7
LbrM.32.1620 ⚠
phosphatidylinositol 3-related kinase, putati
— OG7
LbrM.33.2350 ⚠
protein kinase, putative
— OG7
LbrM.35.3080 ⚠
hypothetical protein, conserved
— OG7
LbrM.20.1390 ⚠
Nucleoporin NUP225
— OG7
LbrM.24.1720 ⚠
SpoU rRNA Methylase family, putative
— OG7
LbrM.26.1490 ⚠
farnesyltransferase beta subunit
— OG7
LbrM.28.2080 ⚠
p21-C-terminal region-binding protein, putati
— OG7
LbrM.30.0640 ⚠
hypothetical protein, conserved
— OG7
LbrM.35.7120 ⚠
beta adaptin, putative
— OG7
LbrM.20.3550 ⚠
target of rapamycin kinase 3, putative
— OG7
LbrM.28.1620 ⚠
Cell division control protein 48, putative
— OG7
LbrM.22.0060 ⚠
transcription factor-like protein
— OG7
LbrM.18.1310 ⚠
bifunctional aminoacyl-tRNA synthetase, putat
— OG7
LbrM.34.2670 ⚠
hypothetical protein, conserved
— OG7
LbrM.31.0480 ⚠
CRAL/TRIO domain containing protein, putative
— OG7
LbrM.20.2350 ⚠
hypothetical protein, conserved
— OG7
LbrM.20.3990 ⚠
Phosphatidylinositol 3-kinase tor2
— OG7
LbrM.31.0410 ⚠
CRAL/TRIO domain containing protein, putative
— OG7
LbrM.32.2890 ⚠
SpoU rRNA Methylase family, putative
— OG7
LbrM.21.1130 ⚠
aspartyl-tRNA synthetase, putative
— OG7
LbrM.35.1470 ⚠
hypothetical protein, conserved
— OG7
LbrM.32.1520 ⚠
RNA capping enzyme, cytoplasmic
— OG7
LbrM.35.1480 ⚠
adenylate kinase, putative
— OG7
LbrM.30.3450 ⚠
hypothetical protein, conserved
— OG7
LbrM.33.2430 ⚠
hypothetical protein, conserved
— OG7
LbrM.30.3750 ⚠
CPSF-domain protein, putative
— OG7
LbrM.05.0860 ⚠
CPSF A subunit region, putative
— OG7
LbrM.23.0610 ⚠
hypothetical protein, conserved
— OG7
LbrM.35.3160 ⚠
phosphatidylinositol 3- and 4-kinase, putativ
— OG7
LbrM.35.5490 ⚠
glycosyl hydrolase, putative
— OG7
LbrM.35.5980 ⚠
hypothetical protein, conserved
— OG7
LbrM.31.1440 ⚠
Protein of unknown function (DUF3638)/Protein
— OG7
LbrM.27.0890 ⚠
parallel beta-helix repeat, putative
— OG7
LbrM.20.1840 ⚠
asparaginyl-tRNA synthetase, putative
— OG7
LbrM.34.3110 ⚠
RNA-binding protein, putative
— OG7
LbrM.31.3340 ⚠
acetyl-CoA carboxylase
— OG7
LbrM.21.1070 ⚠
hypothetical protein, conserved
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.