LbrM.18.1310

bifunctional aminoacyl-tRNA synthetase, putative, prolyl-tRNA synthetase, putative

Leishmania braziliensis MHOM/BR/75/M2904 OG6: OG6_100749 OG7: OG7_0002333 191 interactions (filtered)

Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used

Source datasets

T.brucei_2016_Gazestani

T.brucei_2017_Crozier

L.donovani_2025_Azimi

T.cruzi_2025_Azimi

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Network view up to 80 partners

Query Computational only Exp + computational Experimental only

Interactions 191 total

Partner	Experimental (Co-frac/MS)	Computational (OG inference)	OG
LbrM.18.0610 hypothetical protein, conserved	—	OG6 LdBPK_180550.1 ↔ LdBPK_181230.1 OG6 TCSYLVIO_006181 ↔ TCSYLVIO_006246 OG7 TCSYLVIO_006181 ↔ TCSYLVIO_006246 OG7 LdBPK_180550.1 ↔ LdBPK_181230.1	Both
LbrM.24.2100 tubulin folding cofactor D, putative	—	OG6 LdBPK_181220.1 ↔ LdBPK_242100.1 OG6 LdBPK_181230.1 ↔ LdBPK_242100.1 OG6 TCSYLVIO_001302 ↔ TCSYLVIO_006246 OG7 LdBPK_181220.1 ↔ LdBPK_242100.1 +2 more	Both
LbrM.22.0580 guide RNA associated protein, GAP2, putative	—	OG6 LdBPK_181230.1 ↔ LdBPK_220520.1 OG6 TCSYLVIO_001262 ↔ TCSYLVIO_006246 OG7 LdBPK_181230.1 ↔ LdBPK_220520.1 OG7 TCSYLVIO_001262 ↔ TCSYLVIO_006246	Both
LbrM.21.1130 ⚠ aspartyl-tRNA synthetase, putative	—	OG6 TCSYLVIO_003107 ↔ TCSYLVIO_006246 OG7 LdBPK_181220.1 ↔ LdBPK_342110.1 OG7 LdBPK_181230.1 ↔ LdBPK_342110.1 OG7 TCSYLVIO_003107 ↔ TCSYLVIO_006246	Both
LbrM.30.0540 ⚠ aspartyl-tRNA synthetase, putative	—	OG6 TCSYLVIO_003107 ↔ TCSYLVIO_006246 OG7 LdBPK_181220.1 ↔ LdBPK_342110.1 OG7 LdBPK_181230.1 ↔ LdBPK_342110.1 OG7 TCSYLVIO_003107 ↔ TCSYLVIO_006246	Both
LbrM.20.1840 ⚠ asparaginyl-tRNA synthetase, putative	—	OG6 LdBPK_181220.1 ↔ LdBPK_342110.1 OG6 LdBPK_181230.1 ↔ LdBPK_342110.1 OG7 LdBPK_181220.1 ↔ LdBPK_342110.1 OG7 LdBPK_181230.1 ↔ LdBPK_342110.1 +1 more	Both
LbrM.18.1380 hypothetical protein, conserved	—	OG6 TCSYLVIO_006238 ↔ TCSYLVIO_006246 OG6 LdBPK_181230.1 ↔ LdBPK_181300.1 OG7 LdBPK_181230.1 ↔ LdBPK_181300.1 OG7 TCSYLVIO_006238 ↔ TCSYLVIO_006246	Both
LbrM.33.2190 ribosome assembly protein RRB1, putative	—	OG6 TCSYLVIO_005619 ↔ TCSYLVIO_006246 OG6 LdBPK_181230.1 ↔ LdBPK_332020.1 OG7 LdBPK_181230.1 ↔ LdBPK_332020.1 OG7 TCSYLVIO_005619 ↔ TCSYLVIO_006246	Both
LbrM.12.0270 cysteinyl-tRNA synthetase, putative	—	OG6 LdBPK_120255.1 ↔ LdBPK_181220.1 OG6 LdBPK_120255.1 ↔ LdBPK_181230.1 OG6 Tb927.10.12890 ↔ Tb927.6.950 OG7 Tb927.10.12890 ↔ Tb927.6.950 +2 more	Both
LbrM.08.0470 WD domain, G-beta repeat, putative	—	OG6 LdBPK_080420.1 ↔ LdBPK_181220.1 OG6 LdBPK_080420.1 ↔ LdBPK_181230.1 OG7 LdBPK_080420.1 ↔ LdBPK_181220.1 OG7 LdBPK_080420.1 ↔ LdBPK_181230.1	Both
LbrM.32.1170 ⚠ small nuclear ribonucleoprotein, putative	—	OG7 LdBPK_181230.1 ↔ LdBPK_260010.1	OG7
LbrM.14.0800 ⚠ protein kinase, putative	—	OG7 TCSYLVIO_006246 ↔ TCSYLVIO_009362	OG7
LbrM.30.0820 ⚠ co-chaperone GrpE, putative	—	OG7 LdBPK_181230.1 ↔ LdBPK_300770.1	OG7
LbrM.28.2700 ⚠ Eukaryotic translation initiation factor 4E-3	—	OG7 LdBPK_181220.1 ↔ LdBPK_300460.1 OG7 LdBPK_181230.1 ↔ LdBPK_300460.1	OG7
LbrM.32.0820 ⚠ Outer row dynein-assembly protein 7	—	OG7 LdBPK_181220.1 ↔ LdBPK_261200.1 OG7 LdBPK_181230.1 ↔ LdBPK_261200.1	OG7
LbrM.34.5330 ⚠ HECT-domain (ubiquitin-transferase), putative	—	OG7 LdBPK_181230.1 ↔ LdBPK_300970.1 OG7 LdBPK_161180.1 ↔ LdBPK_181220.1 OG7 LdBPK_161180.1 ↔ LdBPK_181230.1	OG7
LbrM.34.3160 ⚠ replication factor C, subunit 3, putative	—	OG7 LdBPK_181220.1 ↔ LdBPK_241010.1 OG7 LdBPK_181230.1 ↔ LdBPK_241010.1	OG7
LbrM.27.1750 ⚠ Eukaryotic translation initiation factor 4E-1	—	OG7 LdBPK_181220.1 ↔ LdBPK_300460.1 OG7 LdBPK_181230.1 ↔ LdBPK_300460.1	OG7
LbrM.01.0190 ⚠ LSM domain containing protein, putative	—	OG7 LdBPK_181230.1 ↔ LdBPK_260010.1	OG7
LbrM.33.2840 ⚠ metallo-peptidase, Clan MF, Family M17	—	OG7 LdBPK_110640.1 ↔ LdBPK_181220.1 OG7 LdBPK_110640.1 ↔ LdBPK_181230.1	OG7
LbrM.05.0820 ⚠ zinc-finger of a C2HC-type, putative	—	OG7 TCSYLVIO_006138 ↔ TCSYLVIO_006246	OG7
LbrM.35.0580 ⚠ zinc-finger of a C2HC-type, putative	—	OG7 TCSYLVIO_006138 ↔ TCSYLVIO_006246	OG7
LbrM.29.0550 ⚠ zinc-finger of a C2HC-type, putative	—	OG7 TCSYLVIO_006138 ↔ TCSYLVIO_006246	OG7
LbrM.13.0750 N(2), N(2)-dimethylguanosine tRNA methyltrans	—	OG6 TCSYLVIO_002844 ↔ TCSYLVIO_006246 OG7 TCSYLVIO_002844 ↔ TCSYLVIO_006246	Both
LbrM.18.0090 ⚠ zinc-finger of a C2HC-type/Double zinc ribbon	—	OG6 TCSYLVIO_006138 ↔ TCSYLVIO_006246 OG7 TCSYLVIO_006138 ↔ TCSYLVIO_006246	Both
LbrM.35.4480 paraflagellar rod component, putative	—	OG6 TCSYLVIO_004736 ↔ TCSYLVIO_006246	OG6
LbrM.06.0920 ⚠ hypothetical protein, conserved	—	OG7 LdBPK_030430.1 ↔ LdBPK_181220.1 OG7 LdBPK_030430.1 ↔ LdBPK_181230.1	OG7
LbrM.35.2170 ⚠ TLD, putative	—	OG7 LdBPK_030430.1 ↔ LdBPK_181220.1 OG7 LdBPK_030430.1 ↔ LdBPK_181230.1	OG7
LbrM.18.1100 5-oxoprolinase, putative	—	OG6 LdBPK_181050.1 ↔ LdBPK_181220.1 OG6 LdBPK_181050.1 ↔ LdBPK_181230.1 OG7 LdBPK_181050.1 ↔ LdBPK_181220.1 OG7 LdBPK_181050.1 ↔ LdBPK_181230.1	Both
LbrM.30.1350 Zinc finger, C3HC4 type (RING finger), putati	—	OG6 TCSYLVIO_003179 ↔ TCSYLVIO_006246 OG7 TCSYLVIO_003179 ↔ TCSYLVIO_006246	Both
LbrM.02.0360 Soluble NSF attachment protein, SNAP, putativ	—	OG6 LdBPK_020280.1 ↔ LdBPK_181220.1 OG6 LdBPK_020280.1 ↔ LdBPK_181230.1 OG7 LdBPK_020280.1 ↔ LdBPK_181220.1 OG7 LdBPK_020280.1 ↔ LdBPK_181230.1	Both
LbrM.26.1240 ⚠ hypothetical protein, conserved	—	OG6 LdBPK_181220.1 ↔ LdBPK_261200.1 OG6 LdBPK_181230.1 ↔ LdBPK_261200.1 OG7 LdBPK_181220.1 ↔ LdBPK_261200.1 OG7 LdBPK_181230.1 ↔ LdBPK_261200.1	Both
LbrM.31.1600 hypothetical protein, conserved	—	OG7 TCSYLVIO_002919 ↔ TCSYLVIO_006246	OG7
LbrM.23.0350 hypothetical protein, conserved	—	OG6 LdBPK_181220.1 ↔ LdBPK_230360.1 OG6 LdBPK_181230.1 ↔ LdBPK_230360.1 OG7 LdBPK_181220.1 ↔ LdBPK_230360.1 OG7 LdBPK_181230.1 ↔ LdBPK_230360.1	Both
LbrM.17.0790 ⚠ GMP reductase	—	OG6 LdBPK_181220.1 ↔ LdBPK_191590.1 OG6 LdBPK_181230.1 ↔ LdBPK_191590.1	OG6
LbrM.34.2670 hypothetical protein, conserved	—	OG6 LdBPK_181220.1 ↔ LdBPK_352820.1 OG6 LdBPK_181230.1 ↔ LdBPK_352820.1 OG7 LdBPK_181220.1 ↔ LdBPK_352820.1 OG7 LdBPK_181230.1 ↔ LdBPK_352820.1	Both
LbrM.22.0060 ⚠ transcription factor-like protein	—	OG6 LdBPK_181220.1 ↔ LdBPK_220007.1 OG6 LdBPK_181230.1 ↔ LdBPK_220007.1 OG7 LdBPK_181220.1 ↔ LdBPK_220007.1 OG7 LdBPK_181230.1 ↔ LdBPK_220007.1	Both
LbrM.24.1000 ⚠ replication factor C, subunit 1, putative	—	OG6 LdBPK_181220.1 ↔ LdBPK_241010.1 OG6 LdBPK_181230.1 ↔ LdBPK_241010.1 OG7 LdBPK_181220.1 ↔ LdBPK_241010.1 OG7 LdBPK_181230.1 ↔ LdBPK_241010.1	Both
LbrM.33.0400 DNA mismatch repair protein MSH2, putative	—	OG6 LdBPK_181230.1 ↔ LdBPK_330420.1 OG7 LdBPK_181230.1 ↔ LdBPK_330420.1	Both
LbrM.26.1200 hypothetical protein, conserved	—	OG6 LdBPK_181230.1 ↔ LdBPK_261160.1 OG7 LdBPK_181230.1 ↔ LdBPK_261160.1	Both
LbrM.30.0640 hypothetical protein, conserved	—	OG6 LdBPK_181220.1 ↔ LdBPK_300580.1 OG6 LdBPK_181230.1 ↔ LdBPK_300580.1 OG7 LdBPK_181220.1 ↔ LdBPK_300580.1 OG7 LdBPK_181230.1 ↔ LdBPK_300580.1	Both
LbrM.33.2150 hypothetical protein, conserved	—	OG6 LdBPK_181220.1 ↔ LdBPK_331980.1 OG6 LdBPK_181230.1 ↔ LdBPK_331980.1 OG7 LdBPK_181220.1 ↔ LdBPK_331980.1 OG7 LdBPK_181230.1 ↔ LdBPK_331980.1	Both
LbrM.28.2080 p21-C-terminal region-binding protein, putati	—	OG6 LdBPK_181220.1 ↔ LdBPK_282030.1 OG6 LdBPK_181230.1 ↔ LdBPK_282030.1 OG7 LdBPK_181220.1 ↔ LdBPK_282030.1 OG7 LdBPK_181230.1 ↔ LdBPK_282030.1	Both
LbrM.22.0530 Uncharacterised protein family UPF0066, putat	—	OG6 TCSYLVIO_001255 ↔ TCSYLVIO_006246 OG7 TCSYLVIO_001255 ↔ TCSYLVIO_006246	Both
LbrM.12.0530 ⚠ WW domain containing protein, putative	—	OG6 LdBPK_120470.1 ↔ LdBPK_181220.1 OG6 LdBPK_120470.1 ↔ LdBPK_181230.1 OG7 LdBPK_120470.1 ↔ LdBPK_181220.1 OG7 LdBPK_120470.1 ↔ LdBPK_181230.1	Both
LbrM.11.0690 hypothetical protein, conserved	—	OG6 LdBPK_110890.1 ↔ LdBPK_181220.1 OG6 LdBPK_110890.1 ↔ LdBPK_181230.1 OG7 LdBPK_110890.1 ↔ LdBPK_181220.1 OG7 LdBPK_110890.1 ↔ LdBPK_181230.1	Both
LbrM.01.0030 DNA-damage inducible protein DDI1-like protei	—	OG6 TCSYLVIO_003428 ↔ TCSYLVIO_006246 OG7 TCSYLVIO_003428 ↔ TCSYLVIO_006246	Both
LbrM.11.0720 Short C-terminal domain/PUB domain containing	—	OG6 LdBPK_110920.1 ↔ LdBPK_181220.1 OG6 LdBPK_110920.1 ↔ LdBPK_181230.1 OG7 LdBPK_110920.1 ↔ LdBPK_181220.1 OG7 LdBPK_110920.1 ↔ LdBPK_181230.1	Both
LbrM.07.0990 Domain of unknown function (DUF3437), putativ	—	OG6 LdBPK_071090.1 ↔ LdBPK_181220.1 OG6 LdBPK_071090.1 ↔ LdBPK_181230.1 OG7 LdBPK_071090.1 ↔ LdBPK_181220.1 OG7 LdBPK_071090.1 ↔ LdBPK_181230.1	Both
LbrM.34.1630 casein kinase II, putative	—	OG6 LdBPK_181220.1 ↔ LdBPK_351720.1 OG6 LdBPK_181230.1 ↔ LdBPK_351720.1	OG6

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