LbrM.01.0190

LSM domain containing protein, putative
Leishmania braziliensis MHOM/BR/75/M2904 OG6: OG6_166948 OG7: OG7_0001217 142 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 142 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LbrM.08.0080 ⚠
ATP-dependent DEAD/H RNA helicase, putative
— OG7
LbrM.26.0020 ⚠
Lsm7p protein, putative
— +2 more OG7
LbrM.32.0470 ⚠
ATP-dependent RNA helicase HEL67
— OG7
LbrM.34.3010 ⚠
ATP-dependent RNA helicase, putative
— OG7
LbrM.28.2270 ⚠
DEAD-box ATP-dependent RNA helicase, mitochon
— OG7
LbrM.35.2370 ⚠
ATP-dependent RNA helicase DBP2A, putative
— OG7
LbrM.32.1170 ⚠
small nuclear ribonucleoprotein, putative
— +2 more OG7
LbrM.07.0360 ⚠
ATP-dependent RNA helicase DBP2B, putative
— OG7
LbrM.34.4440 ⚠
sm-f snRNP core complex protein, putative
— +2 more OG7
LbrM.25.2290 ⚠
LSM domain containing protein, putative
— +2 more OG7
LbrM.10.0140 ⚠
mitochondrial, DEAD/DEAH box helicase, putati
— OG7
LbrM.30.1330 ⚠
small nuclear ribonucleoprotein polypeptide e
— +2 more OG7
LbrM.07.0520 ⚠
hypothetical protein, conserved (fragment)
— OG7
LbrM.20.2310 ⚠
hypothetical protein, conserved
— OG7
LbrM.30.0820 ⚠
co-chaperone GrpE, putative
— OG7
LbrM.20.3660 ⚠
geranylgeranyltransferase, putative
— OG7
LbrM.26.1300 ⚠
hypothetical protein, conserved
— OG7
LbrM.07.0290 ⚠
ubiquitin-protein ligase-like, putative
— OG7
LbrM.34.2670 ⚠
hypothetical protein, conserved
— OG7
LbrM.30.1210 ⚠
WW domain containing protein, putative
— OG7
LbrM.33.0400 ⚠
DNA mismatch repair protein MSH2, putative
— OG7
LbrM.26.1200 ⚠
hypothetical protein, conserved
— OG7
LbrM.34.4530 ⚠
hypothetical protein, conserved
— OG7
LbrM.30.0640 ⚠
hypothetical protein, conserved
— OG7
LbrM.26.1490 ⚠
farnesyltransferase beta subunit
— OG7
LbrM.32.1140 ⚠
hypothetical protein, conserved
— OG7
LbrM.20.3590 ⚠
HECT-domain (ubiquitin-transferase), putative
— OG7
LbrM.33.2190 ⚠
ribosome assembly protein RRB1, putative
— OG7
LbrM.16.1170 ⚠
WW domain containing protein, putative
— OG7
LbrM.29.2460 ⚠
protein kinase, putative
— OG7
LbrM.30.0830 ⚠
heat shock protein grpe, co-chaperone, GrpE,
— OG7
LbrM.35.5900 ⚠
isoleucyl-tRNA synthetase, putative
— OG7
LbrM.35.4610 ⚠
ubiquitin protein ligase, putative
— OG7
LbrM.30.1030 ⚠
ubiquitin-protein ligase, putative
— OG7
LbrM.34.2400 ⚠
ubiquitin-protein ligase, putative
— OG7
LbrM.33.2550 ⚠
glycosyl hydrolase-like protein
— OG7
LbrM.08.0230 ⚠
ubiquitin-activating enzyme-like protein (fra
— OG7
LbrM.19.1330 ⚠
hypothetical protein, unknown function
— OG7
LbrM.15.0090 ⚠
ATP-dependent protease ATPase subunit HslU1,
— OG7
LbrM.09.0230 ⚠
ATP-dependent protease ATPase subunit HslU2
— OG7
LbrM.27.2690 ⚠
hypothetical protein, conserved, WD-repeat pr
— OG7
LbrM.35.2170 ⚠
TLD, putative
— OG7
LbrM.28.2990 ⚠
heat-shock protein hsp70, putative
— OG7
LbrM.28.1300 ⚠
luminal binding protein 1 (BiP), putative
— OG7
LbrM.28.2980 ⚠
heat-shock protein hsp70, putative (fragment)
— OG7
LbrM.01.0790 ⚠
HSP70-like protein
— OG7
LbrM.26.0910 ⚠
chaperone protein-like protein, heat shock 70
— OG7
LbrM.26.1260 ⚠
heat shock protein 70-related protein
— OG7
LbrM.34.4680 ⚠
Hsp70 protein, putative
— OG7
LbrM.06.0920 ⚠
hypothetical protein, conserved
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.