LbrM.19.1330

hypothetical protein, unknown function
Leishmania braziliensis MHOM/BR/75/M2904 OG6: OG6_478725 OG7: OG7_0083836 63 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 63 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LbrM.07.0290 ⚠
ubiquitin-protein ligase-like, putative
— OG7
LbrM.08.0470
WD domain, G-beta repeat, putative
— Both
LbrM.24.1000 ⚠
replication factor C, subunit 1, putative
— Both
LbrM.26.1200
hypothetical protein, conserved
— Both
LbrM.30.0640
hypothetical protein, conserved
— Both
LbrM.26.1490 ⚠
farnesyltransferase beta subunit
— Both
LbrM.32.1140
hypothetical protein, conserved
— Both
LbrM.33.2190
ribosome assembly protein RRB1, putative
— Both
LbrM.01.0690 ⚠
ubiquitin activating enzyme, putative
— OG7
LbrM.01.0190 ⚠
LSM domain containing protein, putative
— OG7
LbrM.34.3160 ⚠
replication factor C, subunit 3, putative
— OG7
LbrM.34.5330 ⚠
HECT-domain (ubiquitin-transferase), putative
— OG7
LbrM.30.0820 ⚠
co-chaperone GrpE, putative
— OG7
LbrM.32.1170 ⚠
small nuclear ribonucleoprotein, putative
— OG7
LbrM.20.3660 ⚠
geranylgeranyltransferase, putative
— OG7
LbrM.17.0530 ⚠
ATPase family associated with various cellula
— OG7
LbrM.33.0400
DNA mismatch repair protein MSH2, putative
— Both
LbrM.30.2590 ⚠
replication factor C, subunit 2, putative
— OG7
LbrM.34.4440 ⚠
sm-f snRNP core complex protein, putative
— OG7
LbrM.30.1210 ⚠
WW domain containing protein, putative
— OG7
LbrM.25.2290 ⚠
LSM domain containing protein, putative
— OG7
LbrM.20.3590 ⚠
HECT-domain (ubiquitin-transferase), putative
— OG7
LbrM.35.7070 ⚠
replication factor C subunit 3, putative
— OG7
LbrM.16.1170 ⚠
WW domain containing protein, putative
— OG7
LbrM.20.5250 ⚠
hypothetical protein, conserved
— OG7
LbrM.27.0660 ⚠
replication factor C, subunit 4, putative
— OG7
LbrM.30.1330 ⚠
small nuclear ribonucleoprotein polypeptide e
— OG7
LbrM.35.4610 ⚠
ubiquitin protein ligase, putative
— OG7
LbrM.34.2400 ⚠
ubiquitin-protein ligase, putative
— OG7
LbrM.06.0920 ⚠
hypothetical protein, conserved
— OG7
LbrM.35.2170 ⚠
TLD, putative
— OG7
LbrM.14.1560 ⚠
tyrosyl-tRNA synthetase, putative
— OG7
LbrM.34.0910
hypothetical protein, conserved
— Both
LbrM.08.0230 ⚠
ubiquitin-activating enzyme-like protein (fra
— Both
LbrM.04.1090
Transcriptional repressor TCF25, putative
— Both
LbrM.03.0410 ⚠
TLD domain protein, conserved
— Both
LbrM.22.0420 ⚠
Putative tRNA binding domain containing prote
— Both
LbrM.18.1380
hypothetical protein, conserved
— Both
LbrM.16.1160 ⚠
tyrosyl or methionyl-tRNA synthetase-like pro
— Both
LbrM.09.1150
hypothetical protein, conserved
— Both
LbrM.02.0150
Ankyrin repeats (3 copies)/Zinc finger, C3HC4
— Both
LbrM.18.1310
bifunctional aminoacyl-tRNA synthetase, putat
— Both
LbrM.11.0720
Short C-terminal domain/PUB domain containing
— Both
LbrM.11.0690
hypothetical protein, conserved
— Both
LbrM.35.5170
hypothetical protein, conserved
— Both
LbrM.32.1190 ⚠
HECT-domain (ubiquitin-transferase), putative
— Both
LbrM.26.0020 ⚠
Lsm7p protein, putative
— Both
LbrM.34.3110
RNA-binding protein, putative
— Both
LbrM.18.0610
hypothetical protein, conserved
— Both
LbrM.34.4770
BRCA1 C Terminus (BRCT) domain containing pro
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.