LbrM.01.0690

ubiquitin activating enzyme, putative
Leishmania braziliensis MHOM/BR/75/M2904 OG6: OG6_101845 OG7: OG7_0003569 127 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 127 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LbrM.03.0820 ⚠
inorganic pyrophosphatase, putative
— OG7
LbrM.19.0110 ⚠
acidocalcisomal pyrophosphatase
— OG7
LbrM.30.0640 ⚠
hypothetical protein, conserved
— OG7
LbrM.33.2190 ⚠
ribosome assembly protein RRB1, putative
— OG7
LbrM.08.0470 ⚠
WD domain, G-beta repeat, putative
— OG7
LbrM.34.0820 ⚠
NADH-dependent fumarate reductase-like protei
— OG7
LbrM.30.0830 ⚠
heat shock protein grpe, co-chaperone, GrpE,
— OG7
LbrM.30.1330 ⚠
small nuclear ribonucleoprotein polypeptide e
— OG7
LbrM.11.0690 ⚠
hypothetical protein, conserved
— OG7
LbrM.11.0720 ⚠
Short C-terminal domain/PUB domain containing
— OG7
LbrM.35.4610 ⚠
ubiquitin protein ligase, putative
— OG7
LbrM.30.1030 ⚠
ubiquitin-protein ligase, putative
— OG7
LbrM.34.2400 ⚠
ubiquitin-protein ligase, putative
— OG7
LbrM.33.2550 ⚠
glycosyl hydrolase-like protein
— OG7
LbrM.35.3310 ⚠
hypothetical protein, conserved
— OG7
LbrM.20.3910 ⚠
nucleolar protein family a, putative
— OG7
LbrM.24.1970 ⚠
WD domain, G-beta repeat/PFU (PLAA family ubi
— OG7
LbrM.34.2360 ⚠
cysteine peptidase, Clan CA, family C19, puta
— OG7
LbrM.27.1390 ⚠
ubiquitin carboxyl-terminal hydrolase, putati
— OG7
LbrM.20.1840 ⚠
asparaginyl-tRNA synthetase, putative
— OG7
LbrM.32.3160 ⚠
cysteine peptidase, Clan CA, family C19, puta
— OG7
LbrM.34.0690 ⚠
vacuolar ATP synthase subunit d, putative
— OG7
LbrM.12.0210 ⚠
ubiquitin hydrolase, putative, cysteine pepti
— OG7
LbrM.21.1130 ⚠
aspartyl-tRNA synthetase, putative
— OG7
LbrM.30.0540 ⚠
aspartyl-tRNA synthetase, putative
— OG7
LbrM.32.0960 ⚠
phenylalanyl-tRNA synthetase alpha chain, put
— OG7
LbrM.10.0160 ⚠
hypothetical protein, conserved
— OG7
LbrM.09.0820 ⚠
ubiquitin ligase, putative
— OG7
LbrM.32.0280 ⚠
Histone chaperone Rttp106-like, putative
— OG7
LbrM.19.1320 ⚠
phenylalanyl-tRNA synthetase, putative
— OG7
LbrM.25.0490 ⚠
hypothetical protein, conserved
— OG7
LbrM.23.1260 ⚠
coronin, putative
— OG7
LbrM.35.2630 ⚠
serine peptidase, Clan SC, Family S9B
— OG7
LbrM.05.0180 ⚠
dihydrolipoamide branched chain transacylase,
— OG7
LbrM.01.0030 ⚠
DNA-damage inducible protein DDI1-like protei
— OG7
LbrM.10.1320 ⚠
hypothetical protein, conserved
— OG7
LbrM.33.0340 ⚠
heat shock protein 83, heat shock protein 83-
— OG7
LbrM.33.0330 ⚠
heat shock protein 83-1
— OG7
LbrM.15.0310 ⚠
ribonucleoprotein p18, mitochondrial precurso
— OG7
LbrM.15.0320 ⚠
ribonucleoprotein p18, mitochondrial precurso
— OG7
LbrM.03.0410 ⚠
TLD domain protein, conserved
— OG7
LbrM.06.0920 ⚠
hypothetical protein, conserved
— OG7
LbrM.35.2170 ⚠
TLD, putative
— OG7
LbrM.24.2100 ⚠
tubulin folding cofactor D, putative
— OG7
LbrM.35.7120 ⚠
beta adaptin, putative
— OG7
LbrM.11.0790 ⚠
adaptin-related protein-like protein
— OG7
LbrM.35.5510 ⚠
Adaptor protein complex AP-3 subunit beta-3
— OG7
LbrM.33.0830 ⚠
ATP synthase F1 subunit gamma protein
— OG7
LbrM.26.1830 ⚠
hypothetical protein, conserved
— OG7
LbrM.29.0780 ⚠
heat shock protein 90, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.