LbrM.35.2630

serine peptidase, Clan SC, Family S9B
Leishmania braziliensis MHOM/BR/75/M2904 OG6: OG6_102236 OG7: OG7_0002160 182 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 182 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LbrM.33.0500 ⚠
SET domain containing protein, putative
— OG7
LbrM.15.0310 ⚠
ribonucleoprotein p18, mitochondrial precurso
— Both
LbrM.15.0320 ⚠
ribonucleoprotein p18, mitochondrial precurso
— Both
LbrM.06.0320 ⚠
oligopeptidase B-like protein, serine peptida
— Both
LbrM.19.0190
NGG1 interacting factor 3-like protein
— Both
LbrM.09.0850 ⚠
oligopeptidase b
— Both
LbrM.26.0050
glycine dehydrogenase, putative
— Both
LbrM.35.7140 ⚠
hypothetical protein
— Both
LbrM.34.4710 ⚠
glyceraldehyde-3-phosphate dehydrogenase-like
— Both
LbrM.34.0420
hypothetical protein, conserved
— Both
LbrM.35.2410 ⚠
NOL1/NOP2/sun family, putative
— Both
LbrM.29.2510 ⚠
NOL1/NOP2/sun family, putative
— Both
LbrM.01.0030
DNA-damage inducible protein DDI1-like protei
— Both
LbrM.29.2090
UDP-glucose:glycoprotein glucosyltransferase,
— Both
LbrM.24.1970
WD domain, G-beta repeat/PFU (PLAA family ubi
— Both
LbrM.35.0120 ⚠
stress-inducible protein STI1 homolog
— OG6
LbrM.27.2600 ⚠
TPR-repeat protein, putative
— OG6
LbrM.25.0170 ⚠
cleavage and polyadenylation specificity fact
— Both
LbrM.22.1440
alanyl-tRNA synthetase, putative
— Both
LbrM.32.0280
Histone chaperone Rttp106-like, putative
— Both
LbrM.20.4500 ⚠
developmentally regulated phosphoprotein-like
— Both
LbrM.28.0460 ⚠
DIS3-like exonuclease, putative
— Both
LbrM.05.0790
hypothetical protein, conserved
— Both
LbrM.23.0650 ⚠
poly(A)-specific ribonuclease PARN, putative
— Both
LbrM.35.6680 ⚠
poly(A)-specific ribonuclease PARN, putative
— Both
LbrM.35.5900
isoleucyl-tRNA synthetase, putative
— Both
LbrM.32.4220
Gar1/Naf1 RNA binding region, putative
— Both
LbrM.10.1320 ⚠
hypothetical protein, conserved
— Both
LbrM.26.1830 ⚠
hypothetical protein, conserved
— Both
LbrM.09.0820
ubiquitin ligase, putative
— Both
LbrM.25.1890
Leucine Rich repeats (2 copies), putative
— Both
LbrM.03.0820 ⚠
inorganic pyrophosphatase, putative
— Both
LbrM.19.0110 ⚠
acidocalcisomal pyrophosphatase
— Both
LbrM.34.0690
vacuolar ATP synthase subunit d, putative
— Both
LbrM.35.4480
paraflagellar rod component, putative
— OG6
LbrM.30.0640
hypothetical protein, conserved
— Both
LbrM.24.2100
tubulin folding cofactor D, putative
— Both
LbrM.19.1110 ⚠
ABC transport system ATP-binding protein, put
— Both
LbrM.28.0340 ⚠
rrp44p homologue, putative
— OG7
LbrM.33.2840 ⚠
metallo-peptidase, Clan MF, Family M17
— OG7
LbrM.04.0360 ⚠
mitochondrial exoribonuclease DSS-1, putative
— OG7
LbrM.20.6030 ⚠
SET domain containing protein, putative
— OG7
LbrM.10.1480 ⚠
SET domain containing protein, putative
— OG7
LbrM.35.7100 ⚠
prolyl endopeptidase
— OG7
LbrM.23.0910 ⚠
SET domain containing protein, putative
— OG7
LbrM.20.1020 ⚠
TPR repeat/SET domain containing protein, put
— OG7
LbrM.34.4210 ⚠
hypothetical protein, conserved
— OG7
LbrM.35.0560 ⚠
dihydrouridine synthase domain protein-like p
— OG7
LbrM.01.0690 ⚠
ubiquitin activating enzyme, putative
— OG7
LbrM.15.1160 ⚠
inositol/phosphatidylinositol phosphatase, pu
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.