LbrM.03.0820

inorganic pyrophosphatase, putative
Leishmania braziliensis MHOM/BR/75/M2904 OG6: OG6_100346 OG7: OG7_0003350 292 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
Applies on "Apply filters".
Reset
⬇ CSV
Network view all shared interactors, plus up to 150 more
Show:

Selection: Shift+drag also box-selects. Drag any selected node to move the whole selection.
Interactions 292 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LbrM.30.0540 ⚠
aspartyl-tRNA synthetase, putative
— OG7
LbrM.01.0690 ⚠
ubiquitin activating enzyme, putative
— OG7
LbrM.21.1130 ⚠
aspartyl-tRNA synthetase, putative
— OG7
LbrM.20.1840 ⚠
asparaginyl-tRNA synthetase, putative
— Both
LbrM.20.5380 ⚠
calpain-like cysteine peptidase, putative, cy
— OG6
LbrM.04.0490 ⚠
cysteine peptidase, Clan CA, family C2, putat
— OG6
LbrM.08.0230 ⚠
ubiquitin-activating enzyme-like protein (fra
— Both
LbrM.23.0120 ⚠
GDP-mannose pyrophosphorylase
— Both
LbrM.20.5390 ⚠
calpain-like cysteine peptidase, putative, cy
— OG6
LbrM.20.5340 ⚠
cysteine peptidase, Clan CA, family C2, putat
— OG6
LbrM.34.0040 ⚠
pyruvate kinase
— Both
LbrM.34.0060 ⚠
pyruvate kinase
— Both
LbrM.34.0070 ⚠
pyruvate kinase, putative (fragment)
— Both
LbrM.34.0010 ⚠
pyruvate kinase
— Both
LbrM.26.1010 ⚠
glucosidase II beta subunit-like protein, put
— Both
LbrM.10.1490 ⚠
hypothetical protein, conserved
— OG7
LbrM.33.2840 ⚠
metallo-peptidase, Clan MF, Family M17
— OG7
LbrM.13.1470 ⚠
Kinesin-13 5, putative
— OG7
LbrM.01.0060 ⚠
Kinesin-13 1, putative
— OG7
LbrM.31.0400 ⚠
Kinesin-13 4, putative
— OG7
LbrM.13.0120 ⚠
Kinesin-13 2, putative
— OG7
LbrM.24.2100 ⚠
tubulin folding cofactor D, putative
— Both
LbrM.34.1330 ⚠
threonyl-tRNA synthetase, putative
— Both
LbrM.35.0200 ⚠
PUB domain containing protein, putative
— Both
LbrM.35.6380 ⚠
disgorgin, putative
— Both
LbrM.33.2190 ⚠
ribosome assembly protein RRB1, putative
— Both
LbrM.01.0030 ⚠
DNA-damage inducible protein DDI1-like protei
— Both
LbrM.22.1120 ⚠
translation initiation factor IF-2, putative
— Both
LbrM.26.1830 ⚠
hypothetical protein, conserved
— Both
LbrM.29.2510 ⚠
NOL1/NOP2/sun family, putative
— Both
LbrM.27.0470 ⚠
Nuclear pore complex protein 158
— Both
LbrM.34.4450 ⚠
Co-chaperone protein P23
— Both
LbrM.20.4840 ⚠
hypothetical protein, conserved
— Both
LbrM.35.0680 ⚠
Elongation factor G1, mitochondrial, putative
— Both
LbrM.10.0310 ⚠
isocitrate dehydrogenase [NADP], mitochondria
— Both
LbrM.34.1100 ⚠
NADH-dependent fumarate reductase, putative
— Both
LbrM.30.0640 ⚠
hypothetical protein, conserved
— Both
LbrM.15.0040 ⚠
Possible lysine decarboxylase, putative
— Both
LbrM.29.2090 ⚠
UDP-glucose:glycoprotein glucosyltransferase,
— Both
LbrM.25.1250 ⚠
NPL4 family, putative
— Both
LbrM.25.1070 ⚠
TAP42-like family, putative
— Both
LbrM.18.0110 ⚠
alpha glucosidase II subunit, putative
— Both
LbrM.34.1090 ⚠
NADH-dependent fumarate reductase, putative
— Both
LbrM.35.7120 ⚠
beta adaptin, putative
— Both
LbrM.35.2630 ⚠
serine peptidase, Clan SC, Family S9B
— Both
LbrM.20.3350 ⚠
hypothetical protein, conserved
— Both
LbrM.30.0390 ⚠
kinesin, putative
— OG6
LbrM.13.0900 ⚠
leucyl-tRNA synthetase, putative
— Both
LbrM.10.0200 ⚠
Mitogen-activated protein kinase 10, putative
— OG6
LbrM.14.0460 ⚠
N-terminal conserved domain of Nudc./CS domai
— Both
Page 1 of 6
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.