LbrM.25.1250

NPL4 family, putative
Leishmania braziliensis MHOM/BR/75/M2904 OG6: OG6_101880 OG7: OG7_0007128 153 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 153 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LbrM.27.2510 ⚠
protein phosphatase-like protein
— OG6
LbrM.35.0620 ⚠
protein phosphatase 2C-like protein
— OG6
LbrM.30.0990 ⚠
protein phosphatase 2C, putative (fragment)
— OG6
LbrM.32.1860 ⚠
protein phosphatase 2C, putative
— OG6
LbrM.01.0060 ⚠
Kinesin-13 1, putative
— OG7
LbrM.24.0370 ⚠
aspartate aminotransferase, putative
— Both
LbrM.34.0810 ⚠
aspartate aminotransferase, putative
— Both
LbrM.29.1390 ⚠
carnitine/choline acetyltransferase, putative
— Both
LbrM.32.1000
Alpha/beta hydrolase family, putative
— Both
LbrM.32.2280 ⚠
cytidylyltransferase, putative
— Both
LbrM.28.1190
WD domain, G-beta repeat, putative
— Both
LbrM.18.0310 ⚠
dephospho-CoA kinase, putative
— Both
LbrM.28.1220
electron-transfer-flavoprotein, alpha polypep
— Both
LbrM.23.1720
alanine racemase, putative
— Both
LbrM.22.0310
SEP domain containing protein, putative
— Both
LbrM.09.0780
hypothetical protein, conserved
— Both
LbrM.20.3380
phosphomannomutase-like protein
— Both
LbrM.28.2260
tRNA threonylcarbamoyl adenosine modification
— Both
LbrM.01.0250
cyclophilin 12, putative
— OG6
LbrM.31.0140
ubiquitin carboxyl-terminal hydrolase, putati
— Both
LbrM.33.1160
nicotinate phosphoribosyltransferase, putativ
— Both
LbrM.33.3090 ⚠
transcription elongation factor-like protein
— Both
LbrM.35.4810 ⚠
PSP1 C-terminal conserved region, putative
— Both
LbrM.35.2380
hypothetical protein, conserved
— Both
LbrM.28.1870
hypothetical protein, conserved (fragment)
— Both
LbrM.35.4640 ⚠
ATP-dependent DEAD/H RNA helicase, putative
— Both
LbrM.06.1160
Nuclear Dbf2-related kinase
— OG6
LbrM.27.0800 ⚠
UBA/TS-N domain containing protein, putative
— Both
LbrM.03.0820 ⚠
inorganic pyrophosphatase, putative
— Both
LbrM.19.0110 ⚠
acidocalcisomal pyrophosphatase
— Both
LbrM.23.1160
HIT domain containing protein, putative
— Both
LbrM.28.2160 ⚠
Elongation factor G 2, mitochondrial, putativ
— OG7
LbrM.21.0210 ⚠
serine/threonine-protein kinase-like protein
— OG7
LbrM.21.2050 ⚠
hypothetical protein, conserved, RNA polymera
— OG7
LbrM.21.0060 ⚠
hypothetical protein, conserved
— OG7
LbrM.29.1990 ⚠
5'-AMP-activated protein kinase catalytic sub
— OG7
LbrM.28.2190 ⚠
protein lipid droplet kinase (LDK)
— OG7
LbrM.22.0750 ⚠
protein kinase, putative, serine/threonine pr
— OG7
LbrM.06.0520 ⚠
U-box domain containing protein, putative
— OG7
LbrM.32.2690 ⚠
Cid1 family poly A polymerase, putative
— OG7
LbrM.35.1020 ⚠
SNF1-related protein kinases, putative
— OG7
LbrM.33.1980 ⚠
protein kinase, putative
— OG7
LbrM.28.1530 ⚠
hypothetical protein, conserved
— OG7
LbrM.28.1440 ⚠
hypothetical protein, conserved
— OG7
LbrM.28.1510 ⚠
haloacid dehalogenase-like hydrolase-like pro
— OG7
LbrM.28.1490 ⚠
haloacid dehalogenase-like hydrolase-like pro
— OG7
LbrM.25.0910 ⚠
dehydrogenase-like protein
— OG7
LbrM.22.0300 ⚠
carnitine palmitoyltransferase-like protein
— OG7
LbrM.20.3600 ⚠
AP-1 adapter complex gamma subunit, putative
— OG7
LbrM.07.0050 ⚠
alpha-adaptin-like protein
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.