LbrM.21.2050

hypothetical protein, conserved, RNA polymerase II
Leishmania braziliensis MHOM/BR/75/M2904 OG6: OG6_141860 OG7: OG7_0002307 124 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 124 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LbrM.28.2440 ⚠
hd phosphohydrolase family protein
— OG7
LbrM.18.0230 ⚠
Activator of Hsp90 ATPase, N-terminal/Activat
— OG7
LbrM.28.2260 ⚠
tRNA threonylcarbamoyl adenosine modification
— OG7
LbrM.30.1050 ⚠
hypothetical protein, conserved
— OG7
LbrM.29.2080 ⚠
Present in the outer mitochondrial membrane p
— OG7
LbrM.26.1840 ⚠
deoxyhypusine hydroxylase, putative
— OG7
LbrM.25.0120 ⚠
electron transfer flavoprotein, putative
— OG7
LbrM.03.0480 ⚠
quinone oxidoreductase, putative
— OG7
LbrM.18.1050 ⚠
UDP-glucose pyrophosphorylase
— OG7
LbrM.16.1390 ⚠
hypothetical protein, conserved
— OG7
LbrM.33.1160 ⚠
nicotinate phosphoribosyltransferase, putativ
— OG7
LbrM.12.0030 ⚠
PITH domain-containing protein
— OG7
LbrM.27.0800 ⚠
UBA/TS-N domain containing protein, putative
— OG7
LbrM.13.0550 ⚠
ubiquitin-like protein
— OG7
LbrM.35.0650 ⚠
ubiquitin-like protein, putative
— OG7
LbrM.32.0130 ⚠
N-myristoyl transferase, putative
— OG7
LbrM.03.0660 ⚠
hypothetical protein, conserved
— OG7
LbrM.27.1750 ⚠
Eukaryotic translation initiation factor 4E-1
— OG7
LbrM.31.1820 ⚠
diphthine synthase-like protein
— OG7
LbrM.34.0810 ⚠
aspartate aminotransferase, putative
— OG7
LbrM.28.2700 ⚠
Eukaryotic translation initiation factor 4E-3
— OG7
LbrM.19.1750 ⚠
eukaryotic translation initiation factor-like
— OG7
LbrM.24.0370 ⚠
aspartate aminotransferase, putative
— OG7
LbrM.30.0530 ⚠
Eukaryotic translation initiation factor 4E-4
— OG7
LbrM.21.0700 ⚠
phosphoglucomutase, putative
— OG7
LbrM.28.2160 ⚠
Elongation factor G 2, mitochondrial, putativ
— OG7
LbrM.16.0590 ⚠
dihydroorotase, putative
— OG7
LbrM.21.0210 ⚠
serine/threonine-protein kinase-like protein
— OG7
LbrM.33.0090 ⚠
hypothetical protein, conserved
— OG7
LbrM.07.0960 ⚠
protein kinase, putative, serine/threonine ki
— OG7
LbrM.20.1500 ⚠
pyroglutamyl-peptidase I, putative
— OG7
LbrM.29.0800 ⚠
U-box domain protein, putative
— OG7
LbrM.24.0200 ⚠
transcription elongation factor, putative
— OG7
LbrM.33.3090 ⚠
transcription elongation factor-like protein
— OG7
LbrM.35.7010 ⚠
2,3-bisphosphoglycerate-independent phosphogl
— OG7
LbrM.26.0350 ⚠
C-1-tetrahydrofolate synthase, cytoplasmic, p
— OG7
LbrM.31.3170 ⚠
KH domain/Domain of unknown function (DUF1771
— OG7
LbrM.17.1380 ⚠
hypothetical protein, conserved
— OG7
LbrM.01.0240 ⚠
CUE domain/Domain of unknown function (DUF177
— OG7
LbrM.28.1190 ⚠
WD domain, G-beta repeat, putative
— OG7
LbrM.35.6470 ⚠
hypothetical protein, conserved
— OG7
LbrM.25.1570 ⚠
2,4-dihydroxyhept-2-ene-1,7-dioic acid aldola
— OG7
LbrM.21.0070 ⚠
hypothetical protein, conserved
— OG7
LbrM.21.0060 ⚠
hypothetical protein, conserved
— OG7
LbrM.18.0030 ⚠
mevalonate-diphosphate decarboxylase, putativ
— OG7
LbrM.35.1010 ⚠
eukaryotic translation initiation factor 6 (e
— OG7
LbrM.14.1360 ⚠
Bifunctional NAD(P)H-hydrate repair enzyme
— OG7
LbrM.22.0750 ⚠
protein kinase, putative, serine/threonine pr
— OG7
LbrM.18.0720 ⚠
serine/threonine kinase-like protein, putativ
— OG7
LbrM.28.2190 ⚠
protein lipid droplet kinase (LDK)
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.