LbrM.12.0030

PITH domain-containing protein
Leishmania braziliensis MHOM/BR/75/M2904 OG6: OG6_102988 OG7: OG7_0006444 196 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 196 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LbrM.28.1530 ⚠
hypothetical protein, conserved
— OG7
LbrM.28.1490 ⚠
haloacid dehalogenase-like hydrolase-like pro
— OG7
LbrM.28.1440 ⚠
hypothetical protein, conserved
— OG7
LbrM.35.6500
Sucrase/ferredoxin-like, putative
— Both
LbrM.28.1480 ⚠
hypothetical protein, conserved
— OG7
LbrM.28.1510 ⚠
haloacid dehalogenase-like hydrolase-like pro
— Both
LbrM.28.1520 ⚠
haloacid dehalogenase-like hydrolase, putativ
— +1 more Both
LbrM.19.1260 ⚠
FYVE zinc finger, putative
— OG7
LbrM.26.1280 ⚠
hypothetical protein, unknown function
— OG7
LbrM.34.3430 ⚠
zinc finger protein, putative
— OG7
LbrM.27.2620 ⚠
aldo-keto reductase-like protein
— OG7
LbrM.31.3240 ⚠
aldehyde reductase, putative, oxidoreductase,
— OG7
LbrM.10.1490
hypothetical protein, conserved
— OG7
LbrM.32.3910 ⚠
3-hydroxyisobutyryl-coenzyme a hydrolase-like
— OG7
LbrM.32.3900 ⚠
3-hydroxyisobutyryl-coenzyme a hydrolase-like
— OG7
LbrM.13.1470 ⚠
Kinesin-13 5, putative
— OG7
LbrM.01.0060 ⚠
Kinesin-13 1, putative
— OG7
LbrM.31.0400 ⚠
Kinesin-13 4, putative
— OG7
LbrM.13.0120 ⚠
Kinesin-13 2, putative
— OG7
LbrM.34.1170 ⚠
thioredoxin-like protein
— Both
LbrM.20.4840 ⚠
hypothetical protein, conserved
— Both
LbrM.35.0680 ⚠
Elongation factor G1, mitochondrial, putative
— Both
LbrM.10.0310
isocitrate dehydrogenase [NADP], mitochondria
— Both
LbrM.05.0310 ⚠
monothiol glutaredoxin, putative
— Both
LbrM.26.2630 ⚠
6-phosphogluconolactonase
— Both
LbrM.32.1860 ⚠
protein phosphatase 2C, putative
— OG6
LbrM.31.1280
biotin/lipoate protein ligase-like protein
— Both
LbrM.10.0200
Mitogen-activated protein kinase 10, putative
— OG6
LbrM.08.0510
hypothetical protein, conserved
— Both
LbrM.19.0110 ⚠
acidocalcisomal pyrophosphatase
— Both
LbrM.18.1050
UDP-glucose pyrophosphorylase
— Both
LbrM.35.0120 ⚠
stress-inducible protein STI1 homolog
— OG6
LbrM.27.2510 ⚠
protein phosphatase-like protein
— OG6
LbrM.21.0700
phosphoglucomutase, putative
— Both
LbrM.16.0590
dihydroorotase, putative
— Both
LbrM.33.0090
hypothetical protein, conserved
— Both
LbrM.07.0960 ⚠
protein kinase, putative, serine/threonine ki
— Both
LbrM.32.2870 ⚠
superoxide dismutase, putative
— Both
LbrM.20.1500
pyroglutamyl-peptidase I, putative
— Both
LbrM.23.0170
hypothetical protein, conserved
— OG6
LbrM.29.0280
UBX domain-containing protein
— Both
LbrM.32.2010 ⚠
iron superoxide dismutase, putative
— Both
LbrM.18.0720 ⚠
serine/threonine kinase-like protein, putativ
— Both
LbrM.08.0330 ⚠
iron superoxide dismutase A, mitochondrial
— Both
LbrM.32.2000 ⚠
iron superoxide dismutase, putative
— Both
LbrM.27.2600 ⚠
TPR-repeat protein, putative
— OG6
LbrM.30.0990 ⚠
protein phosphatase 2C, putative (fragment)
— OG6
LbrM.35.0620 ⚠
protein phosphatase 2C-like protein
— OG6
LbrM.29.0800 ⚠
U-box domain protein, putative
— Both
LbrM.26.2660 ⚠
6-phosphogluconolactonase
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.