LbrM.27.2600

TPR-repeat protein, putative
Leishmania braziliensis MHOM/BR/75/M2904 OG6: OG6_103410 OG7: OG7_0001150 156 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 156 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LbrM.21.0900 ⚠
methionyl-tRNA synthetase, putative
— OG6
LbrM.32.1000 ⚠
Alpha/beta hydrolase family, putative
— OG6
LbrM.32.2280 ⚠
cytidylyltransferase, putative
— OG6
LbrM.28.1190 ⚠
WD domain, G-beta repeat, putative
— OG6
LbrM.18.0310 ⚠
dephospho-CoA kinase, putative
— OG6
LbrM.27.2510 ⚠
protein phosphatase-like protein
— OG6
LbrM.35.0620 ⚠
protein phosphatase 2C-like protein
— OG6
LbrM.30.0990 ⚠
protein phosphatase 2C, putative (fragment)
— OG6
LbrM.28.1220 ⚠
electron-transfer-flavoprotein, alpha polypep
— OG6
LbrM.23.1720 ⚠
alanine racemase, putative
— OG6
LbrM.32.1860 ⚠
protein phosphatase 2C, putative
— OG6
LbrM.22.0310 ⚠
SEP domain containing protein, putative
— OG6
LbrM.20.3380 ⚠
phosphomannomutase-like protein
— OG6
LbrM.20.1840 ⚠
asparaginyl-tRNA synthetase, putative
— OG6
LbrM.25.0170 ⚠
cleavage and polyadenylation specificity fact
— OG6
LbrM.17.0330 ⚠
dihydrouridine synthase (Dus), putative
— OG6
LbrM.25.2000 ⚠
hypothetical protein, conserved
— OG6
LbrM.20.1500 ⚠
pyroglutamyl-peptidase I, putative
— OG6
LbrM.19.1110 ⚠
ABC transport system ATP-binding protein, put
— OG6
LbrM.34.0420 ⚠
hypothetical protein, conserved
— OG6
LbrM.29.0280 ⚠
UBX domain-containing protein
— OG6
LbrM.25.0750 ⚠
protein kinase, putative
— OG6
LbrM.20.5310 ⚠
Pre-mRNA-splicing factor 38, putative
— OG6
LbrM.27.0360 ⚠
protein kinase, putative
— OG6
LbrM.08.0510 ⚠
hypothetical protein, conserved
— OG6
LbrM.28.2560 ⚠
serine hydroxymethyltransferase (SHMT-L)
— OG6
LbrM.18.0940 ⚠
hypothetical protein, conserved, cyclosporin
— OG6
LbrM.20.4450 ⚠
deoxyhypusine synthase, putative
— OG6
LbrM.14.1560 ⚠
tyrosyl-tRNA synthetase, putative
— OG6
LbrM.34.2630 ⚠
acyl-CoA dehydrogenase, putative
— OG6
LbrM.14.1540 ⚠
myo-inositol-1-phosphate synthase, inositol-3
— OG6
LbrM.23.0120 ⚠
GDP-mannose pyrophosphorylase
— OG6
LbrM.14.1490 ⚠
serine hydroxymethyltranferase (SHMT-S)
— OG6
LbrM.29.0070 ⚠
tryptophanyl-tRNA synthetase, putative
— OG6
LbrM.20.5870 ⚠
tRNA (Uracil-5-)-methyltransferase, putative
— OG6
LbrM.14.1360 ⚠
Bifunctional NAD(P)H-hydrate repair enzyme
— OG6
LbrM.29.0800 ⚠
U-box domain protein, putative
— OG6
LbrM.35.1010 ⚠
eukaryotic translation initiation factor 6 (e
— OG6
LbrM.20.0300 ⚠
deoxyhypusine synthase, putative
— OG6
LbrM.05.0790 ⚠
hypothetical protein, conserved
— OG6
LbrM.35.0680 ⚠
Elongation factor G1, mitochondrial, putative
— OG6
LbrM.28.2260 ⚠
tRNA threonylcarbamoyl adenosine modification
— OG6
LbrM.22.1440 ⚠
alanyl-tRNA synthetase, putative
— OG6
LbrM.21.0070 ⚠
hypothetical protein, conserved
— OG6
LbrM.20.4840 ⚠
hypothetical protein, conserved
— OG6
LbrM.32.0130 ⚠
N-myristoyl transferase, putative
— OG6
LbrM.01.0250 ⚠
cyclophilin 12, putative
— OG6
LbrM.28.0460 ⚠
DIS3-like exonuclease, putative
— OG6
LbrM.16.0590 ⚠
dihydroorotase, putative
— OG6
LbrM.18.1050 ⚠
UDP-glucose pyrophosphorylase
— OG6
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Orthogroup expansion — connections between the query proteins
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How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.