LbrM.32.1000

Alpha/beta hydrolase family, putative
Leishmania braziliensis MHOM/BR/75/M2904 OG6: OG6_102589 OG7: OG7_0007170 161 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 161 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LbrM.30.2560
RNA-binding protein, putative
— OG6
LbrM.28.2700 ⚠
Eukaryotic translation initiation factor 4E-3
— OG7
LbrM.18.1050
UDP-glucose pyrophosphorylase
— Both
LbrM.25.1580
hypothetical protein, conserved
— Both
LbrM.34.4160 ⚠
Protein of unknown function (DUF2009), putati
— Both
LbrM.34.0070 ⚠
pyruvate kinase, putative (fragment)
— Both
LbrM.32.1860 ⚠
protein phosphatase 2C, putative
— OG6
LbrM.26.2630 ⚠
6-phosphogluconolactonase
— Both
LbrM.34.0060 ⚠
pyruvate kinase
— Both
LbrM.34.0040 ⚠
pyruvate kinase
— Both
LbrM.25.1070
TAP42-like family, putative
— Both
LbrM.25.1250
NPL4 family, putative
— Both
LbrM.10.0310
isocitrate dehydrogenase [NADP], mitochondria
— Both
LbrM.35.0680 ⚠
Elongation factor G1, mitochondrial, putative
— Both
LbrM.20.4840 ⚠
hypothetical protein, conserved
— Both
LbrM.34.4450 ⚠
Co-chaperone protein P23
— Both
LbrM.32.2280 ⚠
cytidylyltransferase, putative
— Both
LbrM.28.1190
WD domain, G-beta repeat, putative
— Both
LbrM.18.0310 ⚠
dephospho-CoA kinase, putative
— Both
LbrM.28.1220
electron-transfer-flavoprotein, alpha polypep
— Both
LbrM.23.1720
alanine racemase, putative
— Both
LbrM.22.0310
SEP domain containing protein, putative
— Both
LbrM.20.3380
phosphomannomutase-like protein
— Both
LbrM.28.2260
tRNA threonylcarbamoyl adenosine modification
— Both
LbrM.01.0250
cyclophilin 12, putative
— OG6
LbrM.31.0140
ubiquitin carboxyl-terminal hydrolase, putati
— Both
LbrM.33.3090 ⚠
transcription elongation factor-like protein
— Both
LbrM.31.1640
hypothetical protein, conserved
— Both
LbrM.24.0510
hypothetical protein, conserved
— Both
LbrM.13.0120 ⚠
Kinesin-13 2, putative
— OG7
LbrM.31.0400 ⚠
Kinesin-13 4, putative
— OG7
LbrM.01.0060 ⚠
Kinesin-13 1, putative
— OG7
LbrM.13.1470 ⚠
Kinesin-13 5, putative
— OG7
LbrM.10.1490
hypothetical protein, conserved
— OG7
LbrM.31.3240 ⚠
aldehyde reductase, putative, oxidoreductase,
— OG7
LbrM.27.2620 ⚠
aldo-keto reductase-like protein
— OG7
LbrM.20.3600 ⚠
AP-1 adapter complex gamma subunit, putative
— OG7
LbrM.07.0050 ⚠
alpha-adaptin-like protein
— OG7
LbrM.28.2160 ⚠
Elongation factor G 2, mitochondrial, putativ
— OG7
LbrM.21.0210 ⚠
serine/threonine-protein kinase-like protein
— OG7
LbrM.21.2050 ⚠
hypothetical protein, conserved, RNA polymera
— OG7
LbrM.27.0140 ⚠
WW domain/Zinc finger C-x8-C-x5-C-x3-H type (
— OG7
LbrM.30.3520 ⚠
casein kinase 1 isoform 2, putative
— OG7
LbrM.20.2600 ⚠
protein kinase, putative
— OG7
LbrM.04.1230 ⚠
casein kinase I, putative
— OG7
LbrM.35.6390 ⚠
rab-like GTPase activating protein, putative
— OG7
LbrM.28.1480 ⚠
hypothetical protein, conserved
— OG7
LbrM.28.1510 ⚠
haloacid dehalogenase-like hydrolase-like pro
— OG7
LbrM.28.1440 ⚠
hypothetical protein, conserved
— OG7
LbrM.15.0150 ⚠
zinc finger (CCCH type) protein, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.