LbrM.28.1440

hypothetical protein, conserved
Leishmania braziliensis MHOM/BR/75/M2904 OG6: OG6_200482 OG7: OG7_0005628 175 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 175 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LbrM.12.0030 ⚠
PITH domain-containing protein
— OG7
LbrM.33.2430 ⚠
hypothetical protein, conserved
— OG7
LbrM.20.4400 ⚠
kelch domain-containing protein
— OG7
LbrM.34.0040 ⚠
pyruvate kinase
— OG7
LbrM.32.2690 ⚠
Cid1 family poly A polymerase, putative
— OG7
LbrM.30.0180 ⚠
2-hydroxy-3-oxopropionate reductase, putative
— OG7
LbrM.35.0650 ⚠
ubiquitin-like protein, putative
— OG7
LbrM.25.1070 ⚠
TAP42-like family, putative
— OG7
LbrM.25.1250 ⚠
NPL4 family, putative
— OG7
LbrM.27.2780 ⚠
metallo-peptidase, Clan MA(E), Family M3
— OG7
LbrM.10.0310 ⚠
isocitrate dehydrogenase [NADP], mitochondria
— OG7
LbrM.35.1020 ⚠
SNF1-related protein kinases, putative
— OG7
LbrM.35.0680 ⚠
Elongation factor G1, mitochondrial, putative
— OG7
LbrM.20.4840 ⚠
hypothetical protein, conserved
— OG7
LbrM.18.0310 ⚠
dephospho-CoA kinase, putative
— OG7
LbrM.32.3910 ⚠
3-hydroxyisobutyryl-coenzyme a hydrolase-like
— OG7
LbrM.34.4450 ⚠
Co-chaperone protein P23
— OG7
LbrM.30.0740 ⚠
pdz domain containing protein, putative
— OG7
LbrM.33.1980 ⚠
protein kinase, putative
— OG7
LbrM.35.1610 ⚠
kelch motif containing protein, putative
— OG7
LbrM.19.0110 ⚠
acidocalcisomal pyrophosphatase
— OG7
LbrM.26.2660 ⚠
6-phosphogluconolactonase
— OG7
LbrM.33.0770 ⚠
WD domain, G-beta repeat, putative
— OG7
LbrM.32.3920 ⚠
enoyl-CoA hydratase/isomerase family protein,
— OG7
LbrM.27.2760 ⚠
metallo-peptidase, Clan MA(E), Family M3, pep
— OG7
LbrM.35.4740 ⚠
Protein of unknown function (DUF2870), putati
— OG7
LbrM.29.0800 ⚠
U-box domain protein, putative
— OG7
LbrM.14.1360 ⚠
Bifunctional NAD(P)H-hydrate repair enzyme
— OG7
LbrM.35.1010 ⚠
eukaryotic translation initiation factor 6 (e
— OG7
LbrM.21.0070 ⚠
hypothetical protein, conserved
— OG7
LbrM.19.1750 ⚠
eukaryotic translation initiation factor-like
— OG7
LbrM.25.1710 ⚠
succinyl-CoA synthetase alpha subunit, putati
— OG7
LbrM.25.1700 ⚠
succinyl-CoA synthetase alpha subunit, putati
— OG7
LbrM.32.0130 ⚠
N-myristoyl transferase, putative
— OG7
LbrM.18.0030 ⚠
mevalonate-diphosphate decarboxylase, putativ
— OG7
LbrM.32.1000 ⚠
Alpha/beta hydrolase family, putative
— OG7
LbrM.24.0490 ⚠
Kelch motif/Galactose oxidase, central domain
— OG7
LbrM.29.2080 ⚠
Present in the outer mitochondrial membrane p
— OG7
LbrM.27.1640 ⚠
metallo-peptidase, Clan MA(E), Family M3, pep
— OG7
LbrM.07.0050 ⚠
alpha-adaptin-like protein
— OG7
LbrM.31.3170 ⚠
KH domain/Domain of unknown function (DUF1771
— OG7
LbrM.35.3810 ⚠
Protein of unknown function (DUF2009), putati
— OG7
LbrM.32.2280 ⚠
cytidylyltransferase, putative
— OG7
LbrM.30.0530 ⚠
Eukaryotic translation initiation factor 4E-4
— OG7
LbrM.35.7010 ⚠
2,3-bisphosphoglycerate-independent phosphogl
— OG7
LbrM.35.6610 ⚠
homocysteine S-methyltransferase, putative
— OG7
LbrM.31.2770 ⚠
ferredoxin 2fe-2s-like protein
— OG7
LbrM.35.6500 ⚠
Sucrase/ferredoxin-like, putative
— OG7
LbrM.31.2820 ⚠
ferredoxin 2fe-2s-like protein
— OG7
LbrM.32.2050 ⚠
Cation efflux family, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.