LbrM.25.1700

succinyl-CoA synthetase alpha subunit, putative
Leishmania braziliensis MHOM/BR/75/M2904 OG6: OG6_100834 OG7: OG7_0005210 64 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 64 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LbrM.35.3170 ⚠
succinyl-CoA ligase [GDP-forming] beta-chain,
— +2 more Both
LbrM.32.0130 ⚠
N-myristoyl transferase, putative
— Both
LbrM.13.0880 ⚠
NADH-cytochrome b5 reductase, putative
— OG7
LbrM.32.2570 ⚠
cytochrome-b5 reductase, putative
— OG7
LbrM.27.0810 ⚠
reductase, putative
— OG7
LbrM.19.1020 ⚠
glycosomal malate dehydrogenase
— OG7
LbrM.20.0020 ⚠
malate dehydrogenase, putative
— OG7
LbrM.20.0040 ⚠
malate dehydrogenase, putative
— OG7
LbrM.06.1050 ⚠
deoxyribose-phosphate aldolase, putative
— Both
LbrM.19.0050 ⚠
NADH-cytochrome b5 reductase-like protein
— OG7
LbrM.28.2170 ⚠
ribose 5-phosphate isomerase, putative
— Both
LbrM.10.0200 ⚠
Mitogen-activated protein kinase 10, putative
— OG6
LbrM.28.2440 ⚠
hd phosphohydrolase family protein
— Both
LbrM.20.1500 ⚠
pyroglutamyl-peptidase I, putative
— Both
LbrM.35.4230 ⚠
ATP-dependent protease subunit HslV, putative
— Both
LbrM.20.3380 ⚠
phosphomannomutase-like protein
— Both
LbrM.30.0420 ⚠
phosphatase 2C, putative
— OG6
LbrM.29.1390 ⚠
carnitine/choline acetyltransferase, putative
— Both
LbrM.15.0270 ⚠
sterol carrier protein, putative, nonspecific
— OG7
LbrM.26.0120 ⚠
adenine phosphoribosyltransferase
— OG7
LbrM.32.3900 ⚠
3-hydroxyisobutyryl-coenzyme a hydrolase-like
— OG7
LbrM.32.3910 ⚠
3-hydroxyisobutyryl-coenzyme a hydrolase-like
— OG7
LbrM.22.0300 ⚠
carnitine palmitoyltransferase-like protein
— OG7
LbrM.19.1800 ⚠
choline/Carnitine o-acyltransferase-like prot
— OG7
LbrM.20.3330 ⚠
serine palmitoyltransferase-like protein
— OG7
LbrM.34.0360 ⚠
serine palmitoyltransferase, putative
— OG7
LbrM.28.1530 ⚠
hypothetical protein, conserved
— OG7
LbrM.28.1490 ⚠
haloacid dehalogenase-like hydrolase-like pro
— OG7
LbrM.28.1510 ⚠
haloacid dehalogenase-like hydrolase-like pro
— OG7
LbrM.28.1440 ⚠
hypothetical protein, conserved
— OG7
LbrM.28.1480 ⚠
hypothetical protein, conserved
— OG7
LbrM.20.5150 ⚠
1,2-Dihydroxy-3-keto-5-methylthiopentene diox
— OG7
LbrM.20.4060 ⚠
1,2-Dihydroxy-3-keto-5-methylthiopentene diox
— OG7
LbrM.34.0040 ⚠
pyruvate kinase
— Both
LbrM.24.0780 ⚠
malic enzyme
— Both
LbrM.20.1010 ⚠
uracil phosphoribosyltransferase, putative
— Both
LbrM.23.0840 ⚠
3-ketoacyl-CoA thiolase, putative
— Both
LbrM.22.0710 ⚠
NADH-cytochrome b5 reductase, putative
— Both
LbrM.15.0050 ⚠
cytochrome-b5 reductase, putative
— Both
LbrM.31.2760 ⚠
uridine kinase-like protein
— Both
LbrM.24.2190 ⚠
3-hydroxy-3-methylglutaryl-CoA synthase, puta
— Both
LbrM.31.2810 ⚠
uridine kinase-like protein
— Both
LbrM.22.0720 ⚠
NADH-cytochrome b5 reductase, putative
— Both
LbrM.26.0130 ⚠
adenine phosphoribosyltransferase
— Both
LbrM.10.0310 ⚠
isocitrate dehydrogenase [NADP], mitochondria
— Both
LbrM.35.4740 ⚠
Protein of unknown function (DUF2870), putati
— Both
LbrM.34.0010 ⚠
pyruvate kinase
— Both
LbrM.34.0070 ⚠
pyruvate kinase, putative (fragment)
— Both
LbrM.34.0060 ⚠
pyruvate kinase
— Both
LbrM.24.0790 ⚠
malic enzyme, putative
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.