LbrM.06.1050

deoxyribose-phosphate aldolase, putative
Leishmania braziliensis MHOM/BR/75/M2904 OG6: OG6_102064 OG7: OG7_0007190 62 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 62 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LbrM.28.1440 ⚠
hypothetical protein, conserved
— OG7
LbrM.29.1390 ⚠
carnitine/choline acetyltransferase, putative
— Both
LbrM.32.3600
dihydrolipoamide dehydrogenase, putative
— Both
LbrM.35.4740
Protein of unknown function (DUF2870), putati
— Both
LbrM.25.1710 ⚠
succinyl-CoA synthetase alpha subunit, putati
— Both
LbrM.25.1700 ⚠
succinyl-CoA synthetase alpha subunit, putati
— Both
LbrM.26.2200
nitrilase, putative
— Both
LbrM.32.0130
N-myristoyl transferase, putative
— Both
LbrM.20.3380
phosphomannomutase-like protein
— Both
LbrM.10.0200
Mitogen-activated protein kinase 10, putative
— OG6
LbrM.34.0070 ⚠
pyruvate kinase, putative (fragment)
— Both
LbrM.34.0060 ⚠
pyruvate kinase
— Both
LbrM.34.0040 ⚠
pyruvate kinase
— Both
LbrM.28.1530 ⚠
hypothetical protein, conserved
— OG7
LbrM.28.1490 ⚠
haloacid dehalogenase-like hydrolase-like pro
— OG7
LbrM.28.1510 ⚠
haloacid dehalogenase-like hydrolase-like pro
— OG7
LbrM.28.2440
hd phosphohydrolase family protein
— Both
LbrM.22.0300 ⚠
carnitine palmitoyltransferase-like protein
— OG7
LbrM.19.1800 ⚠
choline/Carnitine o-acyltransferase-like prot
— OG7
LbrM.28.1480 ⚠
hypothetical protein, conserved
— OG7
LbrM.20.0040 ⚠
malate dehydrogenase, putative
— OG7
LbrM.15.0340 ⚠
Ecotin-like protein
— OG7
LbrM.01.0740 ⚠
Eukaryotic initiation factor 4A-1
— OG7
LbrM.29.0500 ⚠
hypothetical protein, conserved
— OG7
LbrM.20.0020 ⚠
malate dehydrogenase, putative
— OG7
LbrM.13.0500 ⚠
Metallopeptidase family M24, putative
— OG7
LbrM.19.1020 ⚠
glycosomal malate dehydrogenase
— OG7
LbrM.28.1700 ⚠
ATP-dependent RNA helicase FAL1, putative
— OG7
LbrM.22.1510 ⚠
ser/thr protein phosphatase, putative
— OG7
LbrM.15.0540 ⚠
ecotin, putative
— OG7
LbrM.35.4690 ⚠
mitochondrial intermediate peptidase, putativ
— OG7
LbrM.27.1650 ⚠
peptidyl dipeptidase, putative, metallo-pepti
— Both
LbrM.15.0550 ⚠
ecotin, putative
— Both
LbrM.25.1930
AGC essential kinase 1
— OG6
LbrM.22.0480 ⚠
peptidyl-prolyl cis-trans isomerase, putative
— Both
LbrM.20.0030 ⚠
malate dehydrogenase
— Both
LbrM.20.0010 ⚠
mitochondrial malate dehydrogenase
— Both
LbrM.17.0570 ⚠
bis(5'-nucleosyl)-tetraphosphatase, symmetric
— Both
LbrM.33.2790
UDP-N-acetylglucosamine pyrophosphorylase, pu
— Both
LbrM.21.1700 ⚠
ATP-dependent RNA helicase SUB2, putative
— Both
LbrM.07.0190
protein phosphatase 2A, regulatory subunit B,
— Both
LbrM.06.1160
Nuclear Dbf2-related kinase
— OG6
LbrM.35.6930
hypothetical protein, conserved, y113g7b.23 p
— Both
LbrM.20.5680
hypothetical protein, conserved
— Both
LbrM.22.0110
GMP synthase [glutamine-hydrolysing]
— Both
LbrM.04.0630
spermidine synthase, putative
— Both
LbrM.16.0750
transaldolase, putative
— Both
LbrM.19.0470 ⚠
metallo-peptidase, Clan MG, Family M24
— Both
LbrM.26.1590 ⚠
metallo-peptidase, Clan MA(E), Family M3, thi
— Both
LbrM.27.2760 ⚠
metallo-peptidase, Clan MA(E), Family M3, pep
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.