LbrM.15.0340

Ecotin-like protein
Leishmania braziliensis MHOM/BR/75/M2904 OG6: OG6_173648 OG7: OG7_0025883 82 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 82 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LbrM.21.1700 ⚠
ATP-dependent RNA helicase SUB2, putative
— OG7
LbrM.35.7070 ⚠
replication factor C subunit 3, putative
— OG7
LbrM.35.5130 ⚠
hypothetical protein, conserved
— OG7
LbrM.28.1700 ⚠
ATP-dependent RNA helicase FAL1, putative
— OG7
LbrM.28.2080 ⚠
p21-C-terminal region-binding protein, putati
— OG7
LbrM.33.2150 ⚠
hypothetical protein, conserved
— OG7
LbrM.26.1240 ⚠
hypothetical protein, conserved
— OG7
LbrM.30.0640 ⚠
hypothetical protein, conserved
— OG7
LbrM.35.6930 ⚠
hypothetical protein, conserved, y113g7b.23 p
— OG7
LbrM.24.1000 ⚠
replication factor C, subunit 1, putative
— OG7
LbrM.30.1210 ⚠
WW domain containing protein, putative
— OG7
LbrM.16.1170 ⚠
WW domain containing protein, putative
— OG7
LbrM.22.0060 ⚠
transcription factor-like protein
— OG7
LbrM.18.1310 ⚠
bifunctional aminoacyl-tRNA synthetase, putat
— OG7
LbrM.19.1020 ⚠
glycosomal malate dehydrogenase
— OG7
LbrM.32.1080 ⚠
Vps23 core domain containing protein, putativ
— OG7
LbrM.23.0350 ⚠
hypothetical protein, conserved
— OG7
LbrM.24.2100 ⚠
tubulin folding cofactor D, putative
— OG7
LbrM.26.2250 ⚠
hypothetical protein, conserved
— OG7
LbrM.30.2590 ⚠
replication factor C, subunit 2, putative
— OG7
LbrM.07.0290 ⚠
ubiquitin-protein ligase-like, putative
— OG7
LbrM.30.1030 ⚠
ubiquitin-protein ligase, putative
— OG7
LbrM.09.1150 ⚠
hypothetical protein, conserved
— OG7
LbrM.11.0730 ⚠
hypothetical protein, conserved
— OG7
LbrM.12.0270 ⚠
cysteinyl-tRNA synthetase, putative
— OG7
LbrM.35.2170 ⚠
TLD, putative
— OG7
LbrM.06.0920 ⚠
hypothetical protein, conserved
— OG7
LbrM.03.0410 ⚠
TLD domain protein, conserved
— OG7
LbrM.08.0470 ⚠
WD domain, G-beta repeat, putative
— OG7
LbrM.33.2730 ⚠
Flagellum attachment zone protein 12
— OG7
LbrM.30.0530 ⚠
Eukaryotic translation initiation factor 4E-4
— OG7
LbrM.13.0500 ⚠
Metallopeptidase family M24, putative
— OG7
LbrM.23.0600 ⚠
5'-3' exoribonuclease C, putative
— OG7
LbrM.22.1510 ⚠
ser/thr protein phosphatase, putative
— OG7
LbrM.33.2790 ⚠
UDP-N-acetylglucosamine pyrophosphorylase, pu
— OG7
LbrM.27.0660 ⚠
replication factor C, subunit 4, putative
— OG7
LbrM.29.0610 ⚠
hypothetical protein, conserved
— OG7
LbrM.19.1750 ⚠
eukaryotic translation initiation factor-like
— OG7
LbrM.33.3020 ⚠
translation initiation factor IF-2, putative
— OG7
LbrM.20.5250 ⚠
hypothetical protein, conserved
— OG7
LbrM.30.0540 ⚠
aspartyl-tRNA synthetase, putative
— OG7
LbrM.02.0670 ⚠
peptidyl dipeptidase, putative, metallo-pepti
— OG7
LbrM.20.1840 ⚠
asparaginyl-tRNA synthetase, putative
— OG7
LbrM.03.0590 ⚠
DEAD/DEAH box helicase, putative
— OG7
LbrM.35.3220 ⚠
ATP-dependent RNA helicase, putative
— OG7
LbrM.07.0990 ⚠
Domain of unknown function (DUF3437), putativ
— OG7
LbrM.10.0330 ⚠
protein transport protein SEC23, putative
— OG7
LbrM.35.6760 ⚠
protein transport protein Sec23-like protein
— OG7
LbrM.11.0720 ⚠
Short C-terminal domain/PUB domain containing
— OG7
LbrM.27.1640 ⚠
metallo-peptidase, Clan MA(E), Family M3, pep
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.