LbrM.03.0590

DEAD/DEAH box helicase, putative
Leishmania braziliensis MHOM/BR/75/M2904 OG6: OG6_105684 OG7: OG7_0002665 154 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 154 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LbrM.27.1750 ⚠
Eukaryotic translation initiation factor 4E-1
— OG7
LbrM.31.3340 ⚠
acetyl-CoA carboxylase
— Both
LbrM.27.0200 ⚠
proteasome alpha 7 subunit, putative
— +1 more Both
LbrM.28.0120 ⚠
proteasome beta 3 subunit, putative
— Both
LbrM.02.0360 ⚠
Soluble NSF attachment protein, SNAP, putativ
— Both
LbrM.19.0080 ⚠
proteasome alpha 7 subunit, putative
— +1 more Both
LbrM.03.0180 ⚠
hypothetical protein
— OG7
LbrM.07.0090 ⚠
cobalamin-dependent methionine synthase, puta
— OG7
LbrM.07.0800 ⚠
hypothetical protein, conserved
— OG7
LbrM.32.2360 ⚠
hypothetical protein, conserved
— OG7
LbrM.20.4740 ⚠
hypothetical protein, conserved
— OG7
LbrM.05.1010 ⚠
methyltransferase-like protein
— OG7
LbrM.32.2420 ⚠
U5 small nuclear ribonucleoprotein component,
— OG7
LbrM.34.2970 ⚠
ubiquitin-activating enzyme E1, putative
— OG7
LbrM.25.1640 ⚠
elongation factor 2-like protein
— OG7
LbrM.23.0700 ⚠
ubiquitin-activating enzyme E1, putative
— OG7
LbrM.35.0260 ⚠
elongation factor 2
— OG7
LbrM.35.0250 ⚠
elongation factor 2
— OG7
LbrM.35.0270 ⚠
elongation factor 2
— OG7
LbrM.35.7280 ⚠
T-complex protein 1, theta subunit, putative
— OG7
LbrM.27.1370 ⚠
T-complex protein 1, beta subunit, putative
— OG7
LbrM.13.1520 ⚠
chaperonin TCP20, putative
— OG7
LbrM.34.3840 ⚠
T-complex protein 1, eta subunit, putative
— OG7
LbrM.35.1750 ⚠
proteasome subunit alpha type-1, putative
— OG7
LbrM.35.1840 ⚠
proteasome subunit beta type-5, putative
— OG7
LbrM.14.0310 ⚠
proteasome alpha 3 subunit, putative
— OG7
LbrM.08.0540 ⚠
ribose-phosphate pyrophosphokinase, putative
— OG7
LbrM.33.0890 ⚠
proteasome subunit alpha type-5, putative
— OG7
LbrM.34.2250 ⚠
hypothetical protein, conserved
— OG7
LbrM.25.0910 ⚠
dehydrogenase-like protein
— OG7
LbrM.30.0180 ⚠
2-hydroxy-3-oxopropionate reductase, putative
— OG7
LbrM.33.2160 ⚠
hypothetical protein, conserved
— OG7
LbrM.20.3840 ⚠
hypothetical protein, conserved
— OG7
LbrM.34.2630 ⚠
acyl-CoA dehydrogenase, putative
— OG7
LbrM.33.0160 ⚠
hypothetical protein, conserved
— OG7
LbrM.35.6170 ⚠
paraflagellar rod component, putative
— OG7
LbrM.34.3430 ⚠
zinc finger protein, putative
— OG7
LbrM.33.2840 ⚠
metallo-peptidase, Clan MF, Family M17
— OG7
LbrM.15.0340 ⚠
Ecotin-like protein
— OG7
LbrM.28.2590 ⚠
WW domain containing protein, putative
— OG7
LbrM.14.1340 ⚠
ras-like small GTPases, putative
— OG7
LbrM.30.0540 ⚠
aspartyl-tRNA synthetase, putative
— OG7
LbrM.20.5250 ⚠
hypothetical protein, conserved
— OG7
LbrM.19.1750 ⚠
eukaryotic translation initiation factor-like
— OG7
LbrM.29.0610 ⚠
hypothetical protein, conserved
— OG7
LbrM.27.0660 ⚠
replication factor C, subunit 4, putative
— OG7
LbrM.10.0191 ⚠
hypothetical protein, conserved
— OG7
LbrM.15.0540 ⚠
ecotin, putative
— OG7
LbrM.26.1280 ⚠
hypothetical protein, unknown function
— OG7
LbrM.35.2170 ⚠
TLD, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.