LbrM.31.3340

acetyl-CoA carboxylase
Leishmania braziliensis MHOM/BR/75/M2904 OG6: OG6_101052 OG7: OG7_0001434 194 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 194 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LbrM.08.0900 ⚠
phosphoribosylpyrophosphate synthetase
— +5 more Both
LbrM.08.0540 ⚠
ribose-phosphate pyrophosphokinase, putative
— +5 more Both
LbrM.35.5650 ⚠
phosphoribosylpyrophosphate synthetase, putat
— +6 more Both
LbrM.33.2210 ⚠
phosphoribosyl transferase, putative, phospho
— +6 more Both
LbrM.32.1560 ⚠
ATP-dependent DNA DEAD/DEAH box helicase, put
— OG7
LbrM.02.0170 ⚠
RNA helicase, putative (fragment)
— OG7
LbrM.23.1500 ⚠
DNA polymerase theta (helicase domain only),
— OG7
LbrM.31.2950 ⚠
RNA polymerase ii largest subunit
— Both
LbrM.20.0330 ⚠
DNA-directed RNA polymerase III subunit C1, p
— Both
LbrM.05.1110 ⚠
DNA-directed RNA polymerase I largest subunit
— Both
LbrM.16.1400 ⚠
DNA-directed rna polymerase I largest subunit
— Both
LbrM.17.0940 ⚠
ATP-dependent RNA helicase, putative
— Both
LbrM.13.0320 ⚠
ATP-dependent RNA helicase, putative
— Both
LbrM.05.0510 ⚠
ATP synthase F1, alpha subunit, putative (fra
— Both
LbrM.28.2310 ⚠
Cullin family/Cullin protein neddylation doma
— OG7
LbrM.35.2620 ⚠
Cullin protein neddylation domain containing
— OG7
LbrM.35.3280 ⚠
cullin-like protein
— OG7
LbrM.16.1260 ⚠
Cullin family/Cullin protein neddylation doma
— OG7
LbrM.24.2370 ⚠
cullin-like protein-like protein
— OG7
LbrM.10.0900
hypothetical protein, conserved
— OG7
LbrM.34.3840 ⚠
T-complex protein 1, eta subunit, putative
— OG7
LbrM.13.1520 ⚠
chaperonin TCP20, putative
— OG7
LbrM.27.1370 ⚠
T-complex protein 1, beta subunit, putative
— OG7
LbrM.35.7280 ⚠
T-complex protein 1, theta subunit, putative
— OG7
LbrM.30.1030 ⚠
ubiquitin-protein ligase, putative
— OG7
LbrM.16.1170 ⚠
WW domain containing protein, putative
— OG7
LbrM.07.0290 ⚠
ubiquitin-protein ligase-like, putative
— OG7
LbrM.34.5330 ⚠
HECT-domain (ubiquitin-transferase), putative
— OG7
LbrM.31.0270 ⚠
DNA-directed RNA polymerase II subunit 2, put
— OG7
LbrM.18.0910
hypothetical protein, conserved
— Both
LbrM.32.3060
proteasome regulatory non-ATP-ase subunit, pu
— Both
LbrM.29.1550
hypothetical protein, conserved
— Both
LbrM.34.3940
PRP8 protein homologue, putative, U5 snRNA-as
— Both
LbrM.34.4810 ⚠
proteasome alpha 1 subunit, putative
— Both
LbrM.20.0320
eukaryotic translation initiation factor 5, p
— Both
LbrM.03.0140
acetyltransferase, putative
— Both
LbrM.25.1240 ⚠
Cullin family/Cullin protein neddylation doma
— Both
LbrM.30.1210 ⚠
WW domain containing protein, putative
— Both
LbrM.23.0610
hypothetical protein, conserved
— Both
LbrM.08.0010 ⚠
adaptor complex protein (AP) 3 delta subunit
— Both
LbrM.30.3630
ATP synthase, epsilon chain, putative
— Both
LbrM.29.1870
hypothetical protein, conserved
— Both
LbrM.27.0890
parallel beta-helix repeat, putative
— Both
LbrM.19.0080 ⚠
proteasome alpha 7 subunit, putative
— Both
LbrM.35.1840 ⚠
proteasome subunit beta type-5, putative
— OG7
LbrM.05.0520 ⚠
ATP synthase F1, alpha subunit, putative
— Both
LbrM.30.1400
hypothetical protein, conserved
— Both
LbrM.23.0130 ⚠
Concanavalin A-like lectin/glucanases superfa
— Both
LbrM.31.1440
Protein of unknown function (DUF3638)/Protein
— Both
LbrM.14.0550
WD domain, G-beta repeat, putative
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.