LbrM.18.0910

hypothetical protein, conserved
Leishmania braziliensis MHOM/BR/75/M2904 OG6: OG6_102176 OG7: OG7_0007065 172 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 172 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LbrM.03.0170 ⚠
ABC transporter protein, putative
— +2 more Both
LbrM.31.1440
Protein of unknown function (DUF3638)/Protein
— +2 more Both
LbrM.19.1110 ⚠
ABC transport system ATP-binding protein, put
— OG7
LbrM.33.0320 ⚠
ATP-binding cassette sub-family F member 1, p
— OG7
LbrM.23.0610
hypothetical protein, conserved
— +2 more Both
LbrM.20.1740
Glycosyl hydrolase family 65 central catalyti
— +2 more Both
LbrM.35.5490
glycosyl hydrolase, putative
— +2 more Both
LbrM.34.2360 ⚠
cysteine peptidase, Clan CA, family C19, puta
— OG7
LbrM.27.1390 ⚠
ubiquitin carboxyl-terminal hydrolase, putati
— OG7
LbrM.32.3160 ⚠
cysteine peptidase, Clan CA, family C19, puta
— +1 more Both
LbrM.12.0210 ⚠
ubiquitin hydrolase, putative, cysteine pepti
— Both
LbrM.02.0130 ⚠
phosphatidylinositol kinase related protein,
— OG7
LbrM.08.0900 ⚠
phosphoribosylpyrophosphate synthetase
— OG7
LbrM.33.2210 ⚠
phosphoribosyl transferase, putative, phospho
— OG7
LbrM.13.0070 ⚠
mitochondrial DNA polymerase I protein B, put
— OG7
LbrM.04.1230 ⚠
casein kinase I, putative
— OG7
LbrM.20.2600 ⚠
protein kinase, putative
— OG7
LbrM.30.3520 ⚠
casein kinase 1 isoform 2, putative
— OG7
LbrM.34.0990 ⚠
casein kinase I, putative
— OG7
LbrM.27.1900 ⚠
casein kinase I-like protein
— OG7
LbrM.25.2430 ⚠
casein kinase I, putative
— OG7
LbrM.13.1120 ⚠
AAA domain/Dpy-30 motif containing protein, p
— OG7
LbrM.10.0900
hypothetical protein, conserved
— OG7
LbrM.34.1640 ⚠
ubiquitin hydrolase, putative, cysteine pepti
— OG7
LbrM.20.3690 ⚠
cysteine peptidase, Clan CA, family C19, puta
— OG7
LbrM.12.0330 ⚠
hypothetical protein, conserved
— OG7
LbrM.12.0320 ⚠
hypothetical protein, conserved
— OG7
LbrM.31.2950 ⚠
RNA polymerase ii largest subunit
— OG7
LbrM.20.0330 ⚠
DNA-directed RNA polymerase III subunit C1, p
— OG7
LbrM.32.1560 ⚠
ATP-dependent DNA DEAD/DEAH box helicase, put
— OG7
LbrM.02.0170 ⚠
RNA helicase, putative (fragment)
— OG7
LbrM.23.1500 ⚠
DNA polymerase theta (helicase domain only),
— OG7
LbrM.27.0450 ⚠
ATPase, putative
— OG7
LbrM.30.2490 ⚠
AAA family ATPase-like protein
— OG7
LbrM.20.3100 ⚠
peroxisome biosynthesis protein-like protein
— OG7
LbrM.27.1140 ⚠
vesicular transport protein (CDC48 homologue)
— OG7
LbrM.11.0710 ⚠
ATPase, putative
— OG7
LbrM.20.5780 ⚠
cell division cycle protein-like protein
— OG7
LbrM.16.0070 ⚠
peroxisome assembly protein, putative
— OG7
LbrM.26.0410 ⚠
RNA editing 3' terminal uridylyl transferase
— OG7
LbrM.20.0970 ⚠
myosin IB heavy chain, putative
— OG7
LbrM.14.0930 ⚠
RNA editing 3' terminal uridylyl transferase
— OG7
LbrM.28.0820 ⚠
kinetoplast poly(A) polymerase 1
— OG7
LbrM.34.3430 ⚠
zinc finger protein, putative
— OG7
LbrM.32.1520 ⚠
RNA capping enzyme, cytoplasmic
— OG7
LbrM.35.6620 ⚠
Phosphatidylinositol 3-kinase tor1
— OG7
LbrM.20.4090 ⚠
DNA-directed RNA polymerase III, putative
— OG7
LbrM.29.0150 ⚠
DNA-directed RNA polymerase II subunit 3, put
— OG7
LbrM.06.0510 ⚠
SpoU rRNA Methylase family, putative
— OG7
LbrM.30.1030 ⚠
ubiquitin-protein ligase, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.