LbrM.20.3690

cysteine peptidase, Clan CA, family C19, putative, ubiquitin hydrolase, putative
Leishmania braziliensis MHOM/BR/75/M2904 OG6: OG6_173868 OG7: OG7_0002166 237 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 237 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LbrM.04.0070 ⚠
cAMP-specific phosphodiesterase, putative
— Both
LbrM.33.0320 ⚠
ATP-binding cassette sub-family F member 1, p
— Both
LbrM.03.0170 ⚠
ABC transporter protein, putative
— OG7
LbrM.19.1110 ⚠
ABC transport system ATP-binding protein, put
— OG7
LbrM.23.0700 ⚠
ubiquitin-activating enzyme E1, putative
— Both
LbrM.34.2970 ⚠
ubiquitin-activating enzyme E1, putative
— Both
LbrM.28.0240 ⚠
hypothetical protein, unknown function
— OG7
LbrM.21.1350 ⚠
hypothetical protein, conserved
— OG7
LbrM.17.0210 ⚠
WD domain, G-beta repeat, putative
— OG7
LbrM.35.7070 ⚠
replication factor C subunit 3, putative
— OG7
LbrM.35.3290 ⚠
fibrillarin
— OG7
LbrM.20.3590 ⚠
HECT-domain (ubiquitin-transferase), putative
— OG7
LbrM.17.0410 ⚠
hypothetical protein, conserved
— OG7
LbrM.26.1670 ⚠
hypothetical protein, conserved
— OG7
LbrM.31.1940 ⚠
hypothetical protein, conserved
— OG7
LbrM.33.3230 ⚠
hypothetical protein, conserved
— OG7
LbrM.32.0060 ⚠
nuclear segregation protein, putative
— OG7
LbrM.33.2150 ⚠
hypothetical protein, conserved
— OG7
LbrM.34.2110 ⚠
hypothetical protein, conserved
— OG7
LbrM.26.2040 ⚠
hypothetical protein, conserved
— OG7
LbrM.24.1000 ⚠
replication factor C, subunit 1, putative
— OG7
LbrM.29.1550 ⚠
hypothetical protein, conserved
— OG7
LbrM.30.2690 ⚠
Stabilization of polarity axis, putative
— OG7
LbrM.13.0920 ⚠
RNA-binding protein RBP10, putative, DNA-dire
— OG7
LbrM.19.0410 ⚠
fibrillarin, putative
— OG7
LbrM.30.2590 ⚠
replication factor C, subunit 2, putative
— OG7
LbrM.32.1530 ⚠
G5-interacting protein, putative
— OG7
LbrM.17.0530 ⚠
ATPase family associated with various cellula
— OG7
LbrM.25.1280 ⚠
DNA-directed RNA polymerase I subunit RPB10,
— OG7
LbrM.13.1360 ⚠
hypothetical protein, conserved
— OG7
LbrM.35.2670 ⚠
hypothetical protein, conserved
— OG7
LbrM.35.6450 ⚠
hypothetical protein, conserved
— OG7
LbrM.24.0630 ⚠
ubiquitin carboxyl-terminal hydrolase, putati
— OG7
LbrM.30.3470 ⚠
protein mkt1, putative
— OG7
LbrM.34.3270 ⚠
Putative death-receptor fusion protein (DUF24
— OG7
LbrM.33.2680 ⚠
ras-like small GTPases, putative
— OG7
LbrM.05.0470 ⚠
GTPase, putative
— OG7
LbrM.23.0340 ⚠
hypothetical protein, conserved
— OG7
LbrM.18.0910 ⚠
hypothetical protein, conserved
— OG7
LbrM.26.0760 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LbrM.35.2810 ⚠
cyclin-e binding protein 1-like protein
— OG7
LbrM.17.0220 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LbrM.31.3070 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LbrM.11.0100 ⚠
regulator of chromatin condensation, putative
— OG7
LbrM.35.4300 ⚠
regulator of chromosome condensation 1-like p
— OG7
LbrM.26.0750 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LbrM.33.3240 ⚠
hypothetical protein, conserved
— OG7
LbrM.34.1530 ⚠
Concanavalin A-like lectin/glucanases superfa
— OG7
LbrM.28.2690 ⚠
hypothetical protein, conserved
— OG7
LbrM.34.3160 ⚠
replication factor C, subunit 3, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.