LbrM.17.0530

ATPase family associated with various cellular activities (AAA), putative
Leishmania braziliensis MHOM/BR/75/M2904 OG6: OG6_142131 OG7: OG7_0001167 125 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 125 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LbrM.22.0580 ⚠
guide RNA associated protein, GAP2, putative
— OG7
LbrM.33.3020 ⚠
translation initiation factor IF-2, putative
— OG7
LbrM.29.2460 ⚠
protein kinase, putative
— OG7
LbrM.19.1750 ⚠
eukaryotic translation initiation factor-like
— OG7
LbrM.27.0660 ⚠
replication factor C, subunit 4, putative
— OG7
LbrM.30.0830 ⚠
heat shock protein grpe, co-chaperone, GrpE,
— OG7
LbrM.20.5260 ⚠
MORN repeat-containing protein
— OG7
LbrM.15.1420 ⚠
mismatch repair protein MSH3, putative
— OG7
LbrM.30.1330 ⚠
small nuclear ribonucleoprotein polypeptide e
— OG7
LbrM.35.4610 ⚠
ubiquitin protein ligase, putative
— OG7
LbrM.30.1030 ⚠
ubiquitin-protein ligase, putative
— OG7
LbrM.30.0530 ⚠
Eukaryotic translation initiation factor 4E-4
— OG7
LbrM.34.2400 ⚠
ubiquitin-protein ligase, putative
— OG7
LbrM.35.6040 ⚠
Rab3 GTPase-activating protein regulatory sub
— OG7
LbrM.33.2550 ⚠
glycosyl hydrolase-like protein
— OG7
LbrM.33.2730 ⚠
Flagellum attachment zone protein 12
— OG7
LbrM.35.2160 ⚠
DNA mismatch repair protein MSH6, putative
— OG7
LbrM.18.1380 ⚠
hypothetical protein, conserved
— OG7
LbrM.19.0260 ⚠
protein kinase
— OG7
LbrM.20.1650 ⚠
eukaryotic translation initiation factor 2-al
— OG7
LbrM.01.0690 ⚠
ubiquitin activating enzyme, putative
— OG7
LbrM.08.0230 ⚠
ubiquitin-activating enzyme-like protein (fra
— OG7
LbrM.34.1640 ⚠
ubiquitin hydrolase, putative, cysteine pepti
— OG7
LbrM.20.3690 ⚠
cysteine peptidase, Clan CA, family C19, puta
— OG7
LbrM.15.1240 ⚠
cysteine peptidase, Clan CA, family C19, puta
— OG7
LbrM.19.1330 ⚠
hypothetical protein, unknown function
— OG7
LbrM.17.1250 ⚠
WW domain containing protein, putative
— OG7
LbrM.12.0530 ⚠
WW domain containing protein, putative
— OG7
LbrM.28.2590 ⚠
WW domain containing protein, putative
— OG7
LbrM.08.0730 ⚠
Beta-lactamase superfamily domain containing
— OG7
LbrM.13.0440 ⚠
hypothetical protein, conserved
— OG7
LbrM.21.1070 ⚠
hypothetical protein, conserved
— OG7
LbrM.15.0340 ⚠
Ecotin-like protein
— OG7
LbrM.19.0970 ⚠
hypothetical protein, conserved
— OG7
LbrM.23.0350 ⚠
hypothetical protein, conserved
— OG7
LbrM.23.0600 ⚠
5'-3' exoribonuclease C, putative
— OG7
LbrM.09.1150 ⚠
hypothetical protein, conserved
— OG7
LbrM.11.0730 ⚠
hypothetical protein, conserved
— OG7
LbrM.12.0270 ⚠
cysteinyl-tRNA synthetase, putative
— OG7
LbrM.35.2170 ⚠
TLD, putative
— OG7
LbrM.06.0920 ⚠
hypothetical protein, conserved
— OG7
LbrM.03.0410 ⚠
TLD domain protein, conserved
— OG7
LbrM.20.5000 ⚠
hypothetical protein, conserved
— OG7
LbrM.08.0110 ⚠
hypothetical protein, unknown function
— OG7
LbrM.19.1320 ⚠
phenylalanyl-tRNA synthetase, putative
— OG7
LbrM.08.0470 ⚠
WD domain, G-beta repeat, putative
— OG7
LbrM.15.0540 ⚠
ecotin, putative
— OG7
LbrM.15.0550 ⚠
ecotin, putative
— OG7
LbrM.18.0610 ⚠
hypothetical protein, conserved
— OG7
LbrM.11.0720 ⚠
Short C-terminal domain/PUB domain containing
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.