LbrM.22.0580

guide RNA associated protein, GAP2, putative (fragment)
Leishmania braziliensis MHOM/BR/75/M2904 OG6: OG6_139815 OG7: OG7_0037740 146 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 146 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LbrM.18.0610
hypothetical protein, conserved
— Both
LbrM.33.2190
ribosome assembly protein RRB1, putative
— Both
LbrM.18.1310
bifunctional aminoacyl-tRNA synthetase, putat
— Both
LbrM.18.1380
hypothetical protein, conserved
— Both
LbrM.28.2970 ⚠
heat-shock protein hsp70, putative
— OG6
LbrM.35.2170 ⚠
TLD, putative
— OG7
LbrM.34.0820 ⚠
NADH-dependent fumarate reductase-like protei
— Both
LbrM.35.5680
branch point binding protein, putative
— Both
LbrM.34.1110 ⚠
NADH-dependent fumarate reductase, putative
— Both
LbrM.35.4480
paraflagellar rod component, putative
— OG6
LbrM.24.2100
tubulin folding cofactor D, putative
— Both
LbrM.28.1300 ⚠
luminal binding protein 1 (BiP), putative
— OG6
LbrM.30.0390
kinesin, putative
— OG6
LbrM.13.1350 ⚠
tRNA pseudouridine synthase, putative
— Both
LbrM.30.3300 ⚠
Ankyrin repeats (3 copies), putative
— OG6
LbrM.20.5390 ⚠
calpain-like cysteine peptidase, putative, cy
— OG6
LbrM.20.5340 ⚠
cysteine peptidase, Clan CA, family C2, putat
— OG6
LbrM.28.2990 ⚠
heat-shock protein hsp70, putative
— OG6
LbrM.30.1350
Zinc finger, C3HC4 type (RING finger), putati
— Both
LbrM.25.1790
hypothetical protein, conserved
— Both
LbrM.34.2850 ⚠
Leucine carboxyl methyltransferase/Cupin-like
— Both
LbrM.34.1090 ⚠
NADH-dependent fumarate reductase, putative
— Both
LbrM.34.1100 ⚠
NADH-dependent fumarate reductase, putative
— Both
LbrM.34.0890
hypothetical protein, conserved
— Both
LbrM.01.0030
DNA-damage inducible protein DDI1-like protei
— Both
LbrM.13.0750
N(2), N(2)-dimethylguanosine tRNA methyltrans
— Both
LbrM.28.0700 ⚠
Ankyrin repeats (3 copies), putative
— OG6
LbrM.20.5900
hypothetical protein, conserved
— Both
LbrM.26.0870 ⚠
RNA-editing complex protein MP100, putative
— OG7
LbrM.29.2160 ⚠
Domain of unknown function (DUF4379), putativ
— OG7
LbrM.20.5130 ⚠
conserved protein, unknown function
— OG7
LbrM.01.0690 ⚠
ubiquitin activating enzyme, putative
— OG7
LbrM.01.0190 ⚠
LSM domain containing protein, putative
— OG7
LbrM.34.3160 ⚠
replication factor C, subunit 3, putative
— OG7
LbrM.34.5330 ⚠
HECT-domain (ubiquitin-transferase), putative
— OG7
LbrM.30.0820 ⚠
co-chaperone GrpE, putative
— OG7
LbrM.32.1170 ⚠
small nuclear ribonucleoprotein, putative
— OG7
LbrM.20.3660 ⚠
geranylgeranyltransferase, putative
— OG7
LbrM.17.0530 ⚠
ATPase family associated with various cellula
— OG7
LbrM.35.0220 ⚠
6-phosphofructo-2-kinase/fructose-2,6-bisphos
— OG7
LbrM.33.2090 ⚠
dual-specificity protein kinase, putative
— OG7
LbrM.26.0340 ⚠
6-phosphofructo-2-kinase/fructose-2,6-biphosp
— OG7
LbrM.30.1610 ⚠
pseudouridine synthase A-like protein, putati
— OG7
LbrM.15.0170 ⚠
serine/threonine-protein kinase, putative, pr
— OG7
LbrM.29.0550 ⚠
zinc-finger of a C2HC-type, putative
— OG7
LbrM.35.0580 ⚠
zinc-finger of a C2HC-type, putative
— OG7
LbrM.05.0820 ⚠
zinc-finger of a C2HC-type, putative
— OG7
LbrM.31.1600
hypothetical protein, conserved
— OG7
LbrM.06.0920 ⚠
hypothetical protein, conserved
— OG7
LbrM.35.1560 ⚠
Zn-finger in Ran binding protein and others,
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.