LbrM.20.5340

cysteine peptidase, Clan CA, family C2, putative, calpain-like cysteine peptidase, putative
Leishmania braziliensis MHOM/BR/75/M2904 OG6: OG6_127587 OG7: OG7_0001161 134 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 134 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LbrM.11.0400 ⚠
aminopeptidase, putative, metallo-peptidase,
— OG6
LbrM.11.0410 ⚠
metallo-peptidase, Clan MF, Family M17
— OG6
LbrM.19.0110 ⚠
acidocalcisomal pyrophosphatase
— OG6
LbrM.03.0820 ⚠
inorganic pyrophosphatase, putative
— OG6
LbrM.08.0230 ⚠
ubiquitin-activating enzyme-like protein (fra
— OG6
LbrM.34.2850 ⚠
Leucine carboxyl methyltransferase/Cupin-like
— OG6
LbrM.24.1970 ⚠
WD domain, G-beta repeat/PFU (PLAA family ubi
— OG6
LbrM.25.1540 ⚠
hypothetical protein, conserved
— OG6
LbrM.18.1380 ⚠
hypothetical protein, conserved
— OG6
LbrM.13.0250 ⚠
Flagellar radial spoke protein 4/6
— OG6
LbrM.32.3160 ⚠
cysteine peptidase, Clan CA, family C19, puta
— OG6
LbrM.30.0880 ⚠
hypothetical protein, conserved
— OG6
LbrM.26.1260 ⚠
heat shock protein 70-related protein
— OG6
LbrM.28.3030 ⚠
heat shock protein 70, putative
— OG6
LbrM.28.2980 ⚠
heat-shock protein hsp70, putative (fragment)
— OG6
LbrM.28.2970 ⚠
heat-shock protein hsp70, putative
— OG6
LbrM.28.1300 ⚠
luminal binding protein 1 (BiP), putative
— OG6
LbrM.28.2990 ⚠
heat-shock protein hsp70, putative
— OG6
LbrM.28.0880 ⚠
RNA binding protein rbp16, putative
— OG6
LbrM.34.3270 ⚠
Putative death-receptor fusion protein (DUF24
— OG6
LbrM.28.2940 ⚠
hypothetical protein, conserved
— OG6
LbrM.35.5920 ⚠
Cyclin 12, L-type
— OG6
LbrM.27.2100 ⚠
cdc2-related kinase 9
— OG6
LbrM.24.1240 ⚠
RNA-binding protein 38, putative
— OG6
LbrM.35.1090 ⚠
hypothetical protein, conserved
— OG6
LbrM.35.6040 ⚠
Rab3 GTPase-activating protein regulatory sub
— OG6
LbrM.24.0300 ⚠
hypothetical protein, conserved
— OG6
LbrM.30.2690 ⚠
Stabilization of polarity axis, putative
— OG6
LbrM.23.1570 ⚠
Inositol hexakisphosphate, putative
— OG6
LbrM.05.1080 ⚠
Phosphatidylinositol 4-phosphate 5-kinase, pu
— OG6
LbrM.22.0530 ⚠
Uncharacterised protein family UPF0066, putat
— OG6
LbrM.15.0310 ⚠
ribonucleoprotein p18, mitochondrial precurso
— OG6
LbrM.15.0320 ⚠
ribonucleoprotein p18, mitochondrial precurso
— OG6
LbrM.01.0030 ⚠
DNA-damage inducible protein DDI1-like protei
— OG6
LbrM.34.0010 ⚠
pyruvate kinase
— OG6
LbrM.34.0070 ⚠
pyruvate kinase, putative (fragment)
— OG6
LbrM.34.0060 ⚠
pyruvate kinase
— OG6
LbrM.25.1890 ⚠
Leucine Rich repeats (2 copies), putative
— OG6
LbrM.30.0540 ⚠
aspartyl-tRNA synthetase, putative
— OG6
LbrM.15.1480 ⚠
cAMP specific phosphodiesterase, putative
— OG6
LbrM.15.1250 ⚠
cAMP specific phosphodiesterase, putative
— OG6
LbrM.06.0780 ⚠
hypothetical protein, unknown function
— OG6
LbrM.10.1320 ⚠
hypothetical protein, conserved
— OG6
LbrM.26.1830 ⚠
hypothetical protein, conserved
— OG6
LbrM.09.0230 ⚠
ATP-dependent protease ATPase subunit HslU2
— OG6
LbrM.09.0820 ⚠
ubiquitin ligase, putative
— OG6
LbrM.30.0640 ⚠
hypothetical protein, conserved
— OG6
LbrM.13.0750 ⚠
N(2), N(2)-dimethylguanosine tRNA methyltrans
— OG6
LbrM.15.1050 ⚠
glutamate dehydrogenase
— OG6
LbrM.24.2100 ⚠
tubulin folding cofactor D, putative
— OG6
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.