LbrM.09.0230

ATP-dependent protease ATPase subunit HslU2
Leishmania braziliensis MHOM/BR/75/M2904 OG6: OG6_137689 OG7: OG7_0004131 162 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 162 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LbrM.15.0090 ⚠
ATP-dependent protease ATPase subunit HslU1,
— Both
LbrM.20.3180 ⚠
adenosine kinase-like protein
— OG7
LbrM.34.4150 ⚠
hsp70 subfamily B suppressor 1, elongation fa
— OG7
LbrM.32.2360 ⚠
hypothetical protein, conserved
— OG7
LbrM.22.0310 ⚠
SEP domain containing protein, putative
— OG7
LbrM.02.0190 ⚠
hypothetical protein, conserved
— OG7
LbrM.24.0020 ⚠
clathrin coat assembly protein, putative
— OG7
LbrM.22.1080 ⚠
ChaC-like protein, putative
— OG7
LbrM.27.1990 ⚠
paraflagellar rod protein 5, putative
— OG7
LbrM.29.1830 ⚠
paraflagellar rod protein 1D, putative
— OG7
LbrM.35.0190 ⚠
cap guanine-N7 methyltransferase
— OG7
LbrM.28.1760 ⚠
Galactose oxidase, central domain containing
— OG7
LbrM.01.0190 ⚠
LSM domain containing protein, putative
— OG7
LbrM.20.1520 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LbrM.19.1790 ⚠
FK506-binding protein (FKBP)-type peptidyl-pr
— OG7
LbrM.26.0020 ⚠
Lsm7p protein, putative
— OG7
LbrM.35.0310 ⚠
peptidyl-prolyl cis-trans isomerase, putative
— OG7
LbrM.35.2810 ⚠
cyclin-e binding protein 1-like protein
— OG7
LbrM.24.2170 ⚠
Kelch motif/Galactose oxidase, central domain
— OG7
LbrM.32.1170 ⚠
small nuclear ribonucleoprotein, putative
— OG7
LbrM.17.0220 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LbrM.28.2350 ⚠
hypothetical protein, conserved
— OG7
LbrM.31.3070 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LbrM.22.1310 ⚠
fk506-binding protein 1-like protein
— OG7
LbrM.16.0090 ⚠
Galactose oxidase, central domain/Domain of u
— OG7
LbrM.10.0990 ⚠
FKBP-type peptidyl-prolyl cis-trans isomerase
— OG7
LbrM.20.4400 ⚠
kelch domain-containing protein
— OG7
LbrM.25.2290 ⚠
LSM domain containing protein, putative
— OG7
LbrM.35.1610 ⚠
kelch motif containing protein, putative
— OG7
LbrM.11.0100 ⚠
regulator of chromatin condensation, putative
— OG7
LbrM.35.4300 ⚠
regulator of chromosome condensation 1-like p
— OG7
LbrM.23.0330 ⚠
tryptophanyl-tRNA synthetase, putative
— OG7
LbrM.26.0750 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LbrM.19.1230 ⚠
peptidyl-prolyl cis-trans isomerase, macropha
— OG7
LbrM.24.0490 ⚠
Kelch motif/Galactose oxidase, central domain
— OG7
LbrM.35.6491 ⚠
hypothetical protein, conserved
— OG7
LbrM.29.0670 ⚠
flagellar radial spoke protein-like, putative
— OG7
LbrM.34.2750 ⚠
aminotransferase, putative
— OG7
LbrM.25.0890 ⚠
2OG-Fe(II) oxygenase superfamily, putative
— OG7
LbrM.21.0700 ⚠
phosphoglucomutase, putative
— OG7
LbrM.28.2160 ⚠
Elongation factor G 2, mitochondrial, putativ
— OG7
LbrM.35.4690 ⚠
mitochondrial intermediate peptidase, putativ
— OG7
LbrM.29.0510 ⚠
thymine-7-hydroxylase, putative
— OG7
LbrM.29.2740 ⚠
3',5'-cyclic nucleotide phosphodiesterase, pu
— OG7
LbrM.27.1560 ⚠
choline kinase, ethanolamine kinase, putative
— OG7
LbrM.35.0680 ⚠
Elongation factor G1, mitochondrial, putative
— OG7
LbrM.10.0310 ⚠
isocitrate dehydrogenase [NADP], mitochondria
— OG7
LbrM.18.1190 ⚠
cAMP phosphodiesterase A, putative
— OG7
LbrM.35.3240 ⚠
Ribosomal RNA processing protein 41A
— OG7
LbrM.34.1390 ⚠
choline/ethanolamine kinase, putative
— OG7
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Orthogroup expansion — connections between the query proteins
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How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.